Matches in SemOpenAlex for { <https://semopenalex.org/work/W1522180040> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1522180040 endingPage "1381" @default.
- W1522180040 startingPage "1378" @default.
- W1522180040 abstract "The content of Ca2+-, phospholipid-dependent protein kinase activity (protein kinase C) in murine peritoneal macrophages treated with recombinant interferon-gamma (IFN-gamma) has been investigated. Protein kinase C activity was solubilized by nonionic detergent extraction of sonicated cells and separated by high performance liquid chromatography on a TSK 4000 SW gel filtration column. The enzyme eluted from the column in a molecular weight range of 60-80 X 10(3) and was identified by virtue of Ca2+ and phospholipid requirements. Macrophages treated with recombinant IFN-gamma exhibited a substantial increase in total protein kinase activity which could be accounted for entirely by increased protein kinase C activity. This activity was enhanced as much as 5-fold over that seen in untreated macrophages and was specific for IFN-gamma in that other agents known to signal changes in macrophage function had no effect. The time required for the elevation of kinase activity was identical to that required for induction of other functions by IFN-gamma in macrophages. These observations suggest that protein kinase C may be a focus of regulatory action in IFN-gamma-mediated macrophage activation." @default.
- W1522180040 created "2016-06-24" @default.
- W1522180040 creator A5003506903 @default.
- W1522180040 creator A5012434679 @default.
- W1522180040 creator A5027519120 @default.
- W1522180040 creator A5046571079 @default.
- W1522180040 creator A5051795331 @default.
- W1522180040 date "1985-02-01" @default.
- W1522180040 modified "2023-10-16" @default.
- W1522180040 title "Interferon-gamma modulates protein kinase C activity in murine peritoneal macrophages." @default.
- W1522180040 cites W1483645952 @default.
- W1522180040 cites W1516050685 @default.
- W1522180040 cites W1517412176 @default.
- W1522180040 cites W1594758412 @default.
- W1522180040 cites W1970441944 @default.
- W1522180040 cites W1971333358 @default.
- W1522180040 cites W1973005880 @default.
- W1522180040 cites W1983649348 @default.
- W1522180040 cites W1988958215 @default.
- W1522180040 cites W2001692359 @default.
- W1522180040 cites W2013266934 @default.
- W1522180040 cites W2016568386 @default.
- W1522180040 cites W2066287087 @default.
- W1522180040 cites W2066342343 @default.
- W1522180040 cites W2091315522 @default.
- W1522180040 cites W2093849775 @default.
- W1522180040 cites W2112834292 @default.
- W1522180040 cites W2130802094 @default.
- W1522180040 cites W2159069239 @default.
- W1522180040 cites W2160040629 @default.
- W1522180040 cites W2161798777 @default.
- W1522180040 cites W2214909216 @default.
- W1522180040 cites W4293247451 @default.
- W1522180040 doi "https://doi.org/10.1016/s0021-9258(18)89600-4" @default.
- W1522180040 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3155735" @default.
- W1522180040 hasPublicationYear "1985" @default.
- W1522180040 type Work @default.
- W1522180040 sameAs 1522180040 @default.
- W1522180040 citedByCount "165" @default.
- W1522180040 countsByYear W15221800402014 @default.
- W1522180040 countsByYear W15221800402015 @default.
- W1522180040 countsByYear W15221800402022 @default.
- W1522180040 crossrefType "journal-article" @default.
- W1522180040 hasAuthorship W1522180040A5003506903 @default.
- W1522180040 hasAuthorship W1522180040A5012434679 @default.
- W1522180040 hasAuthorship W1522180040A5027519120 @default.
- W1522180040 hasAuthorship W1522180040A5046571079 @default.
- W1522180040 hasAuthorship W1522180040A5051795331 @default.
- W1522180040 hasBestOaLocation W15221800401 @default.
- W1522180040 hasConcept C153911025 @default.
- W1522180040 hasConcept C159047783 @default.
- W1522180040 hasConcept C184235292 @default.
- W1522180040 hasConcept C185592680 @default.
- W1522180040 hasConcept C202751555 @default.
- W1522180040 hasConcept C2776178377 @default.
- W1522180040 hasConcept C2780841837 @default.
- W1522180040 hasConcept C55493867 @default.
- W1522180040 hasConcept C86803240 @default.
- W1522180040 hasConcept C95444343 @default.
- W1522180040 hasConcept C97029542 @default.
- W1522180040 hasConceptScore W1522180040C153911025 @default.
- W1522180040 hasConceptScore W1522180040C159047783 @default.
- W1522180040 hasConceptScore W1522180040C184235292 @default.
- W1522180040 hasConceptScore W1522180040C185592680 @default.
- W1522180040 hasConceptScore W1522180040C202751555 @default.
- W1522180040 hasConceptScore W1522180040C2776178377 @default.
- W1522180040 hasConceptScore W1522180040C2780841837 @default.
- W1522180040 hasConceptScore W1522180040C55493867 @default.
- W1522180040 hasConceptScore W1522180040C86803240 @default.
- W1522180040 hasConceptScore W1522180040C95444343 @default.
- W1522180040 hasConceptScore W1522180040C97029542 @default.
- W1522180040 hasIssue "3" @default.
- W1522180040 hasLocation W15221800401 @default.
- W1522180040 hasOpenAccess W1522180040 @default.
- W1522180040 hasPrimaryLocation W15221800401 @default.
- W1522180040 hasRelatedWork W1973490230 @default.
- W1522180040 hasRelatedWork W1980758913 @default.
- W1522180040 hasRelatedWork W1987621178 @default.
- W1522180040 hasRelatedWork W1990580490 @default.
- W1522180040 hasRelatedWork W2008585820 @default.
- W1522180040 hasRelatedWork W2025794474 @default.
- W1522180040 hasRelatedWork W2095169768 @default.
- W1522180040 hasRelatedWork W2127971113 @default.
- W1522180040 hasRelatedWork W2287845648 @default.
- W1522180040 hasRelatedWork W4249792496 @default.
- W1522180040 hasVolume "260" @default.
- W1522180040 isParatext "false" @default.
- W1522180040 isRetracted "false" @default.
- W1522180040 magId "1522180040" @default.
- W1522180040 workType "article" @default.