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- W15221966 abstract "The idea that infection may play a causal role in the etiology of leukemia has an antiquity equivalent to the recognition of leukemia as a disease; indeed some early descriptions regarded leukemia as a pathological response to infection rather than a malignancy. It was recognized that the general age-associated incidence of pediatric leukemia appeared to mirror that of common infections such as diphtheria and measles. Reports of infections preceding or copresenting with a diagnosis of leukemia (2,3) were considered to reflect causal linkage although other interpretations of this association were obviously possible. Stewart in particular argued that infections occurring in children prior to diagnosis were likely to have arisen as a consequence of the immunosuppressive effects of leukemia (4). Attempts to implicate infectious spread of leukemia via contact with patients drew negative conclusions (5). These early and incomplete studies therefore left any etiologic association of leukemia and microorganisms unsubstantiated and generally disbelieved." @default.
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- W15221966 date "2000-01-01" @default.
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- W15221966 title "Does Childhood Acute Lymphoblastic Leukemia Have an Infectious Etiology" @default.
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- W15221966 doi "https://doi.org/10.1007/978-1-59259-024-7_25" @default.
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