FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1522768491> ?p ?o ?g. }

• W1522768491 endingPage "795" @default.
• W1522768491 startingPage "785" @default.
• W1522768491 abstract "Here the hypothesis that skeletal muscle Ca(2+)-calmodulin-dependent kinase II (CaMKII) expression and signalling would be modified by endurance training was tested. Eight healthy, young men completed 3 weeks of one-legged endurance exercise training with muscle samples taken from both legs before training and 15 h after the last exercise bout. Along with an approximately 40% increase in mitochondrial F(1)-ATP synthase expression, there was an approximately 1-fold increase in maximal CaMKII activity and CaMKII kinase isoform expression after training in the active leg only. Autonomous CaMKII activity and CaMKII autophosphorylation were increased to a similar extent. However, there was no change in alpha-CaMKII anchoring protein expression with training. Nor was there any change in expression or Thr(17) phosphorylation of the CaMKII substrate phospholamban with training. However, another CaMKII substrate, serum response factor (SRF), had an approximately 60% higher phosphorylation at Ser(103) after training, with no change in SRF expression. There were positive correlations between the increases in CaMKII expression and SRF phosphorylation as well as F(1)ATPase expression with training. After training, there was an increase in cyclic-AMP response element binding protein phosphorylation at Ser(133), but not expression, in muscle of both legs. Taken together, skeletal muscle CaMKII kinase isoform expression and SRF phosphorylation is higher with endurance-type exercise training, adaptations that are restricted to active muscle. This may contribute to greater Ca(2+) mediated regulation during exercise and the altered muscle phenotype with training." @default.
• W1522768491 created "2016-06-24" @default.
• W1522768491 creator A5038378188 @default.
• W1522768491 creator A5038581645 @default.
• W1522768491 creator A5048291477 @default.
• W1522768491 date "2007-08-30" @default.
• W1522768491 modified "2023-10-13" @default.
• W1522768491 title "Effect of endurance exercise training on Ca2+-calmodulin-dependent protein kinase II expression and signalling in skeletal muscle of humans" @default.
• W1522768491 cites W1496238527 @default.
• W1522768491 cites W1543342841 @default.
• W1522768491 cites W1708421313 @default.
• W1522768491 cites W1857652952 @default.
• W1522768491 cites W1900565974 @default.
• W1522768491 cites W1921566650 @default.
• W1522768491 cites W1956566878 @default.
• W1522768491 cites W1963721917 @default.
• W1522768491 cites W1965855977 @default.
• W1522768491 cites W1967769444 @default.
• W1522768491 cites W1968024017 @default.
• W1522768491 cites W1975247334 @default.
• W1522768491 cites W1977840142 @default.
• W1522768491 cites W1981527987 @default.
• W1522768491 cites W1986838242 @default.
• W1522768491 cites W1992256487 @default.
• W1522768491 cites W2003605917 @default.
• W1522768491 cites W2003989812 @default.
• W1522768491 cites W2004655740 @default.
• W1522768491 cites W2006482606 @default.
• W1522768491 cites W2009265893 @default.
• W1522768491 cites W2014325660 @default.
• W1522768491 cites W2017268286 @default.
• W1522768491 cites W2020893322 @default.
• W1522768491 cites W2021968326 @default.
• W1522768491 cites W2022232976 @default.
• W1522768491 cites W2025205439 @default.
• W1522768491 cites W2031233722 @default.
• W1522768491 cites W2040356267 @default.
• W1522768491 cites W2041491674 @default.
• W1522768491 cites W2048771411 @default.
• W1522768491 cites W2056389106 @default.
• W1522768491 cites W2059088759 @default.
• W1522768491 cites W2059733673 @default.
• W1522768491 cites W2060437500 @default.
• W1522768491 cites W2063486797 @default.
• W1522768491 cites W2065408367 @default.
• W1522768491 cites W2066994356 @default.
• W1522768491 cites W2067959799 @default.
• W1522768491 cites W2071994932 @default.
• W1522768491 cites W2072059766 @default.
• W1522768491 cites W2077732889 @default.
• W1522768491 cites W2080546149 @default.
• W1522768491 cites W2082646967 @default.
• W1522768491 cites W2085648653 @default.
• W1522768491 cites W2088094751 @default.
• W1522768491 cites W2088498779 @default.
• W1522768491 cites W2100779832 @default.
• W1522768491 cites W2106889940 @default.
• W1522768491 cites W2113037915 @default.
• W1522768491 cites W2116717165 @default.
• W1522768491 cites W2117978515 @default.
• W1522768491 cites W2122967682 @default.
• W1522768491 cites W2123352794 @default.
• W1522768491 cites W2125391492 @default.
• W1522768491 cites W2125732396 @default.
• W1522768491 cites W2132520315 @default.
• W1522768491 cites W2132886183 @default.
• W1522768491 cites W2137574569 @default.
• W1522768491 cites W2137676389 @default.
• W1522768491 cites W2140147315 @default.
• W1522768491 cites W2140558936 @default.
• W1522768491 cites W2140772050 @default.
• W1522768491 cites W2141840873 @default.
• W1522768491 cites W2142148418 @default.
• W1522768491 cites W2143850042 @default.
• W1522768491 cites W2145135353 @default.
• W1522768491 cites W2146283921 @default.
• W1522768491 cites W2152456372 @default.
• W1522768491 cites W2154449937 @default.
• W1522768491 cites W2154572495 @default.
• W1522768491 cites W2156516623 @default.
• W1522768491 cites W2160458332 @default.
• W1522768491 cites W2161314639 @default.
• W1522768491 cites W2163424879 @default.
• W1522768491 cites W2163785511 @default.
• W1522768491 cites W2165104370 @default.
• W1522768491 cites W2267441065 @default.
• W1522768491 cites W2398734257 @default.
• W1522768491 cites W4253396598 @default.
• W1522768491 cites W4268266 @default.
• W1522768491 cites W58055601 @default.
• W1522768491 doi "https://doi.org/10.1113/jphysiol.2007.138529" @default.
• W1522768491 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2277010" @default.
• W1522768491 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17627985" @default.
• W1522768491 hasPublicationYear "2007" @default.
• W1522768491 type Work @default.
• W1522768491 sameAs 1522768491 @default.
• W1522768491 citedByCount "76" @default.
• W1522768491 countsByYear W15227684912012 @default.

• next