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- W1523425212 abstract "Abstract Rabbits immunized intravitreally with bovine gamma globulin and ovalbumin were challenged intravitreally with both bovine gamma globulin and ovalbumin, with bovine gamma globulin and human serum albumin, or with bovine gamma globulin alone. The specificity demonstrated in the primary response did not appear in rabbits challenged with both antigens; antibody-producing cells of both specificities were found in the uveal tracts of both eyes. Anti-ovalbumin-producing cells were found in the uveal tracts of the rabbits challenged with bovine gamma globulin alone, or with bovine gamma globulin and human serum albumin. Anti-bovine gamma globulin producing cells were also present. No antibody-producing cells were found in the unchallenged eyes of rabbits challenged with bovine gamma globulin alone. The action of a nonspecific soluble enhancing factor is postulated to explain the enhanced response to ovalbumin that resulted when rabbits were challenged with bovine gamma globulin alone." @default.
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- W1523425212 date "1974-03-01" @default.
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- W1523425212 title "Specificity of antibody formation after intravitreal immunization with bovine gamma globulin and ovalbumin" @default.
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- W1523425212 doi "https://doi.org/10.1016/0008-8749(74)90007-0" @default.
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