FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1523520019> ?p ?o ?g. }

• W1523520019 endingPage "645.e1" @default.
• W1523520019 startingPage "635" @default.
• W1523520019 abstract "Study objective We compare the ability of 5 established risk scores to identify patients with suspected acute coronary syndromes who are suitable for discharge after a modified single-presentation high-sensitivity troponin result. Methods This was a prospective observational study conducted in a UK district general hospital emergency department. Consecutive adults recruited with suspected acute coronary syndrome for whom attending physicians determined evaluation with serial troponin testing was required. Index tests were definitions of low risk applied to modified Goldman, Thrombolysis in Myocardial Infarction (TIMI), Global Registry of Acute Cardiac Events (GRACE), History, ECG, Age, Risk Factors, Troponin (HEART), and Vancouver Chest Pain Rule risk scores, incorporating either high-sensitivity troponin T or I results. The endpoint was acute myocardial infarction within 30 days. A test sensitivity threshold for acute myocardial infarction of 98% was chosen. Clinical utility was defined as a negative predictive value greater than or equal to 99.5% and identification of greater than 30% suitable for discharge. Results Nine hundred fifty-nine patients underwent high-sensitivity troponin T analysis and 867 underwent high-sensitivity troponin I analysis. In the high-sensitivity troponin T group, 79 of 959 (8.2%) had an acute myocardial infarction and 66 of 867 (7.6%) in the high-sensitivity troponin I group. Two risk scores (GRACE <80 and HEART ≤3) did not have the potential to achieve a sensitivity of 98% with high-sensitivity troponin T, and 3 scores (Goldman ≤1, TIMI ≤1, and GRACE <80) with high-sensitivity troponin I. A TIMI score of 0 or less than or equal to 1 and modified Goldman score less than or equal to 1 with high-sensitivity troponin T, and TIMI score of 0 and HEART score of less than or equal to 3 with high-sensitivity troponin I had the potential to achieve a negative predictive value greater than or equal to 99.5% while identifying greater than 30% of patients as suitable for immediate discharge. Conclusion With established risk scores, it may be possible to identify greater than 30% of patients suitable for discharge, with a negative predictive value greater than or equal to 99.5% for the diagnosis of acute myocardial infarction, using a single high-sensitivity troponin test result at presentation. There is variation in high-sensitivity troponin assays, which may have implications in introducing rapid rule-out protocols. We compare the ability of 5 established risk scores to identify patients with suspected acute coronary syndromes who are suitable for discharge after a modified single-presentation high-sensitivity troponin result. This was a prospective observational study conducted in a UK district general hospital emergency department. Consecutive adults recruited with suspected acute coronary syndrome for whom attending physicians determined evaluation with serial troponin testing was required. Index tests were definitions of low risk applied to modified Goldman, Thrombolysis in Myocardial Infarction (TIMI), Global Registry of Acute Cardiac Events (GRACE), History, ECG, Age, Risk Factors, Troponin (HEART), and Vancouver Chest Pain Rule risk scores, incorporating either high-sensitivity troponin T or I results. The endpoint was acute myocardial infarction within 30 days. A test sensitivity threshold for acute myocardial infarction of 98% was chosen. Clinical utility was defined as a negative predictive value greater than or equal to 99.5% and identification of greater than 30% suitable for discharge. Nine hundred fifty-nine patients underwent high-sensitivity troponin T analysis and 867 underwent high-sensitivity troponin I analysis. In the high-sensitivity troponin T group, 79 of 959 (8.2%) had an acute myocardial infarction and 66 of 867 (7.6%) in the high-sensitivity troponin I group. Two risk scores (GRACE <80 and HEART ≤3) did not have the potential to achieve a sensitivity of 98% with high-sensitivity troponin T, and 3 scores (Goldman ≤1, TIMI ≤1, and GRACE <80) with high-sensitivity troponin I. A TIMI score of 0 or less than or equal to 1 and modified Goldman score less than or equal to 1 with high-sensitivity troponin T, and TIMI score of 0 and HEART score of less than or equal to 3 with high-sensitivity troponin I had the potential to achieve a negative predictive value greater than or equal to 99.5% while identifying greater than 30% of patients as suitable for immediate discharge. With established risk scores, it may be possible to identify greater than 30% of patients suitable for discharge, with a negative predictive value greater than or equal to 99.5% for the diagnosis of acute myocardial infarction, using a single high-sensitivity troponin test result at presentation. There is variation in high-sensitivity troponin assays, which may have implications in introducing rapid rule-out protocols." @default.
• W1523520019 created "2016-06-24" @default.
• W1523520019 creator A5047478474 @default.
• W1523520019 creator A5058059221 @default.
• W1523520019 creator A5091191993 @default.
• W1523520019 date "2015-12-01" @default.
• W1523520019 modified "2023-09-25" @default.
• W1523520019 title "Identifying Patients Suitable for Discharge After a Single-Presentation High-Sensitivity Troponin Result: A Comparison of Five Established Risk Scores and Two High-Sensitivity Assays" @default.
• W1523520019 cites W1496454720 @default.
• W1523520019 cites W1663156279 @default.
• W1523520019 cites W1994452740 @default.
• W1523520019 cites W2015416871 @default.
• W1523520019 cites W2046265952 @default.
• W1523520019 cites W2063166601 @default.
• W1523520019 cites W2081706508 @default.
• W1523520019 cites W2098002403 @default.
• W1523520019 cites W2098316119 @default.
• W1523520019 cites W2101068188 @default.
• W1523520019 cites W2104295507 @default.
• W1523520019 cites W2114446440 @default.
• W1523520019 cites W2121236256 @default.
• W1523520019 cites W2129303461 @default.
• W1523520019 cites W2132284937 @default.
• W1523520019 cites W2139243268 @default.
• W1523520019 cites W2152267722 @default.
• W1523520019 cites W2168663137 @default.
• W1523520019 cites W2169100788 @default.
• W1523520019 cites W2169735148 @default.
• W1523520019 cites W2317276134 @default.
• W1523520019 cites W4292856638 @default.
• W1523520019 cites W9217911 @default.
• W1523520019 doi "https://doi.org/10.1016/j.annemergmed.2015.07.006" @default.
• W1523520019 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26260100" @default.
• W1523520019 hasPublicationYear "2015" @default.
• W1523520019 type Work @default.
• W1523520019 sameAs 1523520019 @default.
• W1523520019 citedByCount "77" @default.
• W1523520019 countsByYear W15235200192015 @default.
• W1523520019 countsByYear W15235200192016 @default.
• W1523520019 countsByYear W15235200192017 @default.
• W1523520019 countsByYear W15235200192018 @default.
• W1523520019 countsByYear W15235200192019 @default.
• W1523520019 countsByYear W15235200192020 @default.
• W1523520019 countsByYear W15235200192021 @default.
• W1523520019 countsByYear W15235200192022 @default.
• W1523520019 countsByYear W15235200192023 @default.
• W1523520019 crossrefType "journal-article" @default.
• W1523520019 hasAuthorship W1523520019A5047478474 @default.
• W1523520019 hasAuthorship W1523520019A5058059221 @default.
• W1523520019 hasAuthorship W1523520019A5091191993 @default.
• W1523520019 hasBestOaLocation W15235200192 @default.
• W1523520019 hasConcept C115725540 @default.
• W1523520019 hasConcept C118552586 @default.
• W1523520019 hasConcept C126322002 @default.
• W1523520019 hasConcept C144469398 @default.
• W1523520019 hasConcept C164705383 @default.
• W1523520019 hasConcept C188816634 @default.
• W1523520019 hasConcept C2777698277 @default.
• W1523520019 hasConcept C2777785093 @default.
• W1523520019 hasConcept C2777995511 @default.
• W1523520019 hasConcept C2778050738 @default.
• W1523520019 hasConcept C2778704086 @default.
• W1523520019 hasConcept C2779581417 @default.
• W1523520019 hasConcept C2780724011 @default.
• W1523520019 hasConcept C36036425 @default.
• W1523520019 hasConcept C500558357 @default.
• W1523520019 hasConcept C71924100 @default.
• W1523520019 hasConceptScore W1523520019C115725540 @default.
• W1523520019 hasConceptScore W1523520019C118552586 @default.
• W1523520019 hasConceptScore W1523520019C126322002 @default.
• W1523520019 hasConceptScore W1523520019C144469398 @default.
• W1523520019 hasConceptScore W1523520019C164705383 @default.
• W1523520019 hasConceptScore W1523520019C188816634 @default.
• W1523520019 hasConceptScore W1523520019C2777698277 @default.
• W1523520019 hasConceptScore W1523520019C2777785093 @default.
• W1523520019 hasConceptScore W1523520019C2777995511 @default.
• W1523520019 hasConceptScore W1523520019C2778050738 @default.
• W1523520019 hasConceptScore W1523520019C2778704086 @default.
• W1523520019 hasConceptScore W1523520019C2779581417 @default.
• W1523520019 hasConceptScore W1523520019C2780724011 @default.
• W1523520019 hasConceptScore W1523520019C36036425 @default.
• W1523520019 hasConceptScore W1523520019C500558357 @default.
• W1523520019 hasConceptScore W1523520019C71924100 @default.
• W1523520019 hasIssue "6" @default.
• W1523520019 hasLocation W15235200191 @default.
• W1523520019 hasLocation W15235200192 @default.
• W1523520019 hasLocation W15235200193 @default.
• W1523520019 hasLocation W15235200194 @default.
• W1523520019 hasLocation W15235200195 @default.
• W1523520019 hasLocation W15235200196 @default.
• W1523520019 hasLocation W15235200197 @default.
• W1523520019 hasOpenAccess W1523520019 @default.
• W1523520019 hasPrimaryLocation W15235200191 @default.
• W1523520019 hasRelatedWork W2004624427 @default.
• W1523520019 hasRelatedWork W2084334850 @default.
• W1523520019 hasRelatedWork W2115768769 @default.
• W1523520019 hasRelatedWork W2286133741 @default.
• W1523520019 hasRelatedWork W2338206342 @default.

• next