FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1523665785> ?p ?o ?g. }

• W1523665785 endingPage "8390" @default.
• W1523665785 startingPage "8382" @default.
• W1523665785 abstract "African swine fever (ASF) virus is a large enveloped DNA virus assembled in the cytoplasm of cells. In this study, the membrane compartments involved in the envelopment of ASF virus were investigated. A monoclonal antibody recognizing p73, the major structural protein of ASF virus, was generated to analyze the binding of p73 to membranes during the assembly of the virus. Approximately 50% of the intracellular pool of p73 associated with membranes as a peripheral membrane protein. Binding was rapid and complete within 15 min of synthesis. Subcellular membrane fractionation showed that newly synthesized p73 molecules cosedimented with endoplasmic reticulum (ER) membranes and remained associated with the ER during a 2-h chase. A similar distribution on gradients was recorded for p17, a structural membrane protein of ASF virus. The results suggested that the ER was involved in the assembly of ASF virus. A protease protection assay demonstrated a time-dependent envelopment of the membrane bound, but not cytosolic, pool of p73. Envelopment of p73 took place 1 h after binding to membranes and was completed 1 h before the first detection of p73 in virions secreted from cells. Envelopment was unaffected by brefeldin A and monensin, drugs that block membrane transport between the ER and Golgi. Taken together the results provide evidence for the binding of ASF virus structural proteins to a specific membrane compartment and implicate a role for the ER in the assembly and envelopment of ASF virus." @default.
• W1523665785 created "2016-06-24" @default.
• W1523665785 creator A5024618440 @default.
• W1523665785 creator A5034103876 @default.
• W1523665785 creator A5061536703 @default.
• W1523665785 date "1996-12-01" @default.
• W1523665785 modified "2023-10-14" @default.
• W1523665785 title "Involvement of the endoplasmic reticulum in the assembly and envelopment of African swine fever virus" @default.
• W1523665785 cites W1242757451 @default.
• W1523665785 cites W149100299 @default.
• W1523665785 cites W1533755589 @default.
• W1523665785 cites W1541195468 @default.
• W1523665785 cites W1543119869 @default.
• W1523665785 cites W1545152378 @default.
• W1523665785 cites W1570685643 @default.
• W1523665785 cites W1577185738 @default.
• W1523665785 cites W1592548488 @default.
• W1523665785 cites W1595238427 @default.
• W1523665785 cites W1704822668 @default.
• W1523665785 cites W1815705086 @default.
• W1523665785 cites W1836338391 @default.
• W1523665785 cites W1861639525 @default.
• W1523665785 cites W1864893929 @default.
• W1523665785 cites W1935484321 @default.
• W1523665785 cites W1971615608 @default.
• W1523665785 cites W1971944938 @default.
• W1523665785 cites W1975369327 @default.
• W1523665785 cites W1975420002 @default.
• W1523665785 cites W1988518272 @default.
• W1523665785 cites W1990763318 @default.
• W1523665785 cites W1997662437 @default.
• W1523665785 cites W1998917046 @default.
• W1523665785 cites W2001315239 @default.
• W1523665785 cites W2004829063 @default.
• W1523665785 cites W2005411001 @default.
• W1523665785 cites W2005632560 @default.
• W1523665785 cites W2009782062 @default.
• W1523665785 cites W2013436935 @default.
• W1523665785 cites W2023051334 @default.
• W1523665785 cites W2025043105 @default.
• W1523665785 cites W2027792116 @default.
• W1523665785 cites W2037178212 @default.
• W1523665785 cites W2039010111 @default.
• W1523665785 cites W2039622301 @default.
• W1523665785 cites W2041290363 @default.
• W1523665785 cites W2056289299 @default.
• W1523665785 cites W2056917962 @default.
• W1523665785 cites W2082284995 @default.
• W1523665785 cites W2087759132 @default.
• W1523665785 cites W2088902864 @default.
• W1523665785 cites W2092923090 @default.
• W1523665785 cites W2094559945 @default.
• W1523665785 cites W2107312415 @default.
• W1523665785 cites W2127043145 @default.
• W1523665785 cites W2133690500 @default.
• W1523665785 cites W2150198414 @default.
• W1523665785 cites W2400127169 @default.
• W1523665785 cites W303879829 @default.
• W1523665785 cites W394299496 @default.
• W1523665785 cites W81882322 @default.
• W1523665785 doi "https://doi.org/10.1128/jvi.70.12.8382-8390.1996" @default.
• W1523665785 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/190927" @default.
• W1523665785 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8970959" @default.
• W1523665785 hasPublicationYear "1996" @default.
• W1523665785 type Work @default.
• W1523665785 sameAs 1523665785 @default.
• W1523665785 citedByCount "70" @default.
• W1523665785 countsByYear W15236657852012 @default.
• W1523665785 countsByYear W15236657852013 @default.
• W1523665785 countsByYear W15236657852015 @default.
• W1523665785 countsByYear W15236657852016 @default.
• W1523665785 countsByYear W15236657852017 @default.
• W1523665785 countsByYear W15236657852018 @default.
• W1523665785 countsByYear W15236657852021 @default.
• W1523665785 countsByYear W15236657852022 @default.
• W1523665785 countsByYear W15236657852023 @default.
• W1523665785 crossrefType "journal-article" @default.
• W1523665785 hasAuthorship W1523665785A5024618440 @default.
• W1523665785 hasAuthorship W1523665785A5034103876 @default.
• W1523665785 hasAuthorship W1523665785A5061536703 @default.
• W1523665785 hasBestOaLocation W15236657851 @default.
• W1523665785 hasConcept C119062480 @default.
• W1523665785 hasConcept C144647389 @default.
• W1523665785 hasConcept C153911025 @default.
• W1523665785 hasConcept C158617107 @default.
• W1523665785 hasConcept C159047783 @default.
• W1523665785 hasConcept C181199279 @default.
• W1523665785 hasConcept C190062978 @default.
• W1523665785 hasConcept C2522874641 @default.
• W1523665785 hasConcept C27239569 @default.
• W1523665785 hasConcept C2781373781 @default.
• W1523665785 hasConcept C41625074 @default.
• W1523665785 hasConcept C55493867 @default.
• W1523665785 hasConcept C86803240 @default.
• W1523665785 hasConcept C95444343 @default.
• W1523665785 hasConcept C97380033 @default.
• W1523665785 hasConcept C98539663 @default.
• W1523665785 hasConceptScore W1523665785C119062480 @default.

• next