FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1524363497> ?p ?o ?g. }

• W1524363497 abstract "Cardiac arrhythmias represent a leading cause of morbidity and mortality in developed countries. In spite of intense research, the mechanisms of generation, maintenance and termination of theses arrhythmias are still not clearly understood. The ability to predict, prevent and treat these arrhythmias remains a major scientific challenge. In the last years, new technologies have produced a huge amount of information at different levels: subcellular, cellular, tissue, organ and system. However, the knowledge of each component is not sufficient by itself to understand its behavior and an integrative approach, which should take into account the complex interactions between all components is needed. This understanding is necessary to improve prevention and treatment of cardiac arrhythmias. Traditionally, cardiac research has been based on experimental and clinical studies. However, in the last decades, a quantitative understanding of the biophysical and biochemical properties of individual cardiac myocytes and of the anatomical structure of the heart has permitted the development of computational models of single myocytes, portions of tissue and even the whole heart. These models have opened a new approach in studying the complex mechanisms underlying cardiac arrhythmias by means of computer simulations. Integrated and multiscale models of the heart are improving very fast, as a large body of research is being made in this field. These models integrate, with a great degree of detail, the different levels of the organ, from the genetic characteristics of membrane ionic channels, to the electrophysiological characteristics of cardiac cells and to the anatomical structure of the different cardiac tissues. In this chapter, the basis of cardiac multiscale modeling will be reviewed and recent and specific case studies for the different levels will be described focusing on the understanding of cardiac arrhythmias during myocardial ischemia and drug treatment." @default.
• W1524363497 created "2016-06-24" @default.
• W1524363497 creator A5001198057 @default.
• W1524363497 creator A5005803244 @default.
• W1524363497 creator A5012068559 @default.
• W1524363497 creator A5063676325 @default.
• W1524363497 creator A5070750789 @default.
• W1524363497 creator A5070863677 @default.
• W1524363497 date "2011-08-23" @default.
• W1524363497 modified "2023-10-12" @default.
• W1524363497 title "Multiscale Modeling of Myocardial Electrical Activity: From Cell to Organ" @default.
• W1524363497 cites W1926137227 @default.
• W1524363497 cites W1966638935 @default.
• W1524363497 cites W1975869151 @default.
• W1524363497 cites W1985940938 @default.
• W1524363497 cites W1991434231 @default.
• W1524363497 cites W1991649249 @default.
• W1524363497 cites W1996969350 @default.
• W1524363497 cites W1997914936 @default.
• W1524363497 cites W2004492086 @default.
• W1524363497 cites W2007448071 @default.
• W1524363497 cites W2009375605 @default.
• W1524363497 cites W2018812718 @default.
• W1524363497 cites W2024954146 @default.
• W1524363497 cites W2025474013 @default.
• W1524363497 cites W2033882634 @default.
• W1524363497 cites W2034870521 @default.
• W1524363497 cites W2036038468 @default.
• W1524363497 cites W2038131479 @default.
• W1524363497 cites W2040212723 @default.
• W1524363497 cites W2043276871 @default.
• W1524363497 cites W2052615273 @default.
• W1524363497 cites W2058535047 @default.
• W1524363497 cites W2058808011 @default.
• W1524363497 cites W2061451182 @default.
• W1524363497 cites W2064953660 @default.
• W1524363497 cites W2067647989 @default.
• W1524363497 cites W2069884282 @default.
• W1524363497 cites W2070434571 @default.
• W1524363497 cites W2072029467 @default.
• W1524363497 cites W2073521043 @default.
• W1524363497 cites W2077653370 @default.
• W1524363497 cites W2078242986 @default.
• W1524363497 cites W2081864503 @default.
• W1524363497 cites W2083707111 @default.
• W1524363497 cites W2088148771 @default.
• W1524363497 cites W2090696765 @default.
• W1524363497 cites W2091235483 @default.
• W1524363497 cites W2098044063 @default.
• W1524363497 cites W2104749146 @default.
• W1524363497 cites W2107130972 @default.
• W1524363497 cites W2111017573 @default.
• W1524363497 cites W2111191787 @default.
• W1524363497 cites W2112522502 @default.
• W1524363497 cites W2115052737 @default.
• W1524363497 cites W2116411564 @default.
• W1524363497 cites W2121217634 @default.
• W1524363497 cites W2126997063 @default.
• W1524363497 cites W2127318338 @default.
• W1524363497 cites W2127748321 @default.
• W1524363497 cites W2130139165 @default.
• W1524363497 cites W2131127977 @default.
• W1524363497 cites W2132561989 @default.
• W1524363497 cites W2139544996 @default.
• W1524363497 cites W2141571561 @default.
• W1524363497 cites W2150990549 @default.
• W1524363497 cites W2153144629 @default.
• W1524363497 cites W2153475498 @default.
• W1524363497 cites W2163071496 @default.
• W1524363497 cites W2168806904 @default.
• W1524363497 cites W2287216989 @default.
• W1524363497 cites W2287542627 @default.
• W1524363497 cites W2324841714 @default.
• W1524363497 cites W2395169609 @default.
• W1524363497 cites W2415889568 @default.
• W1524363497 cites W64299870 @default.
• W1524363497 cites W2182360689 @default.
• W1524363497 doi "https://doi.org/10.5772/22907" @default.
• W1524363497 hasPublicationYear "2011" @default.
• W1524363497 type Work @default.
• W1524363497 sameAs 1524363497 @default.
• W1524363497 citedByCount "7" @default.
• W1524363497 countsByYear W15243634972012 @default.
• W1524363497 countsByYear W15243634972014 @default.
• W1524363497 countsByYear W15243634972016 @default.
• W1524363497 countsByYear W15243634972017 @default.
• W1524363497 crossrefType "book-chapter" @default.
• W1524363497 hasAuthorship W1524363497A5001198057 @default.
• W1524363497 hasAuthorship W1524363497A5005803244 @default.
• W1524363497 hasAuthorship W1524363497A5012068559 @default.
• W1524363497 hasAuthorship W1524363497A5063676325 @default.
• W1524363497 hasAuthorship W1524363497A5070750789 @default.
• W1524363497 hasAuthorship W1524363497A5070863677 @default.
• W1524363497 hasBestOaLocation W15243634971 @default.
• W1524363497 hasConcept C186060115 @default.
• W1524363497 hasConcept C86803240 @default.
• W1524363497 hasConceptScore W1524363497C186060115 @default.
• W1524363497 hasConceptScore W1524363497C86803240 @default.
• W1524363497 hasLocation W15243634971 @default.
• W1524363497 hasLocation W15243634972 @default.

• next