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- W1524390846 abstract "The evolution of drug resistance is one of the most serious public health problems in modern medicine. In this talk I will present two insights into the problem that are obtained from relatively simple mathematical models involving a separation of ecological and evolutionary timescales: (1) contrary to current orthodoxy, a lighter drug dosage can be most eective for controlling resistance evolution; and (2) cofactors aimed an manipulating within-host ecological interactions can prevent the evolution of resistance. I will also present preliminary data from an experimental test of the latter idea." @default.
- W1524390846 created "2016-06-24" @default.
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- W1524390846 date "2014-06-09" @default.
- W1524390846 modified "2023-09-26" @default.
- W1524390846 title "Insights into the evolution of drug resistance from simple models" @default.
- W1524390846 hasPublicationYear "2014" @default.
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