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- W1524430109 abstract "This chapter reports the findings of retrospective and prospective studies with transcranial magnetic stimulation (TMS) in 129 patients who were referred to the Eleanor and Lou Gehrig MDA/ALS Research Center for the diagnostic evaluation of amyotrophic lateral sclerosis (ALS). The clinical diagnosis of ALS is based on identifying both upper motor neuron (UMN) and lower motor neuron (LMN) signs. Along with avoiding a false diagnosis of ALS, the main impetus of the chapter to develop UMN markers is to be able to make an accurate early diagnosis of ALS in those without initial UMN signs who are later determined to have the disease. TMS assesses structural and functional aspects of UMN involvement, and its combined use with neuroimaging may be more helpful than one individual test. This study is ongoing and when all of the results are available, UMN signs more objectively by combining different types of UMN testing, as opposed to using the clinical examination alone can be predicted." @default.
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- W1524430109 date "2006-01-01" @default.
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- W1524430109 title "Chapter 44 Transcranial magnetic stimulation for upper motor neuron involvement in amyotrophic lateral sclerosis (ALS)" @default.
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- W1524430109 doi "https://doi.org/10.1016/s1567-424x(09)70048-0" @default.
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