Matches in SemOpenAlex for { <https://semopenalex.org/work/W1524514857> ?p ?o ?g. }
- W1524514857 endingPage "8" @default.
- W1524514857 startingPage "1003" @default.
- W1524514857 abstract "To determine peripheral frequencies of CD4+CD25highFoxp3+ regulatory T cells (Treg) in prostate cancer (PCa) patients, and to investigate if there is a correlation between peripheral Treg and total serum prostate specific antigen (PSA) levels in PCa patients.Peripheral blood mononuclear cells from 56 subjects undergoing diagnostic prostate biopsies PSA>/=2.5 ng/ml were analyzed for Treg numbers. Association between the peripheral Treg and serum PSA values was first determined in the entire population, including people with no prostate pathology, PCa, and benign prostate hyperplasia (BPH) patients, and second, in 9 PCa patients before and after curative prostatectomy. In this study, the 3 groups were compared. This project was performed in the Akdeniz University Immunology laboratory, and the Urology outpatient clinic, Antalya, Turkey from December 2008 to January 2010.Peripheral Treg frequencies were significantly increased in the PCa patients (n=19, 3.23+/-1.59) compared with BPH patients (n=27, 1.66+/-0.80), and healthy subjects (n=10, 1.08+/-0.43) (p=0.007). The percentage of Treg in BPH patients was also significantly higher than healthy subjects (p=0.007). The increase of Treg in BPH and PCa patients was positively correlated with total serum PSA levels (r=0.75; p=0.007).Peripheral Treg densities are correlated with PSA in BPH and PCa patients, suggesting that PSA may have a role in Treg induction and/or maintenance." @default.
- W1524514857 created "2016-06-24" @default.
- W1524514857 creator A5012917073 @default.
- W1524514857 creator A5032042230 @default.
- W1524514857 creator A5071350449 @default.
- W1524514857 creator A5074439251 @default.
- W1524514857 creator A5076377253 @default.
- W1524514857 date "2011-10-01" @default.
- W1524514857 modified "2023-09-23" @default.
- W1524514857 title "Increased peripheral CD4+CD25high Treg in prostate cancer patients is correlated with PSA." @default.
- W1524514857 cites W1530782041 @default.
- W1524514857 cites W1560277370 @default.
- W1524514857 cites W1599507531 @default.
- W1524514857 cites W1976407761 @default.
- W1524514857 cites W1988331000 @default.
- W1524514857 cites W1994850185 @default.
- W1524514857 cites W1995570137 @default.
- W1524514857 cites W1996123836 @default.
- W1524514857 cites W1996382553 @default.
- W1524514857 cites W2010397777 @default.
- W1524514857 cites W2010748775 @default.
- W1524514857 cites W2021305251 @default.
- W1524514857 cites W2021603971 @default.
- W1524514857 cites W2030779001 @default.
- W1524514857 cites W2065361773 @default.
- W1524514857 cites W2073310925 @default.
- W1524514857 cites W2073408482 @default.
- W1524514857 cites W2094448081 @default.
- W1524514857 cites W2098574945 @default.
- W1524514857 cites W2099232673 @default.
- W1524514857 cites W2102537478 @default.
- W1524514857 cites W2141785549 @default.
- W1524514857 cites W2142915054 @default.
- W1524514857 cites W2149603665 @default.
- W1524514857 cites W2150345413 @default.
- W1524514857 cites W2152118650 @default.
- W1524514857 cites W2160117150 @default.
- W1524514857 cites W2473345493 @default.
- W1524514857 cites W2916088675 @default.
- W1524514857 cites W2138002048 @default.
- W1524514857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22008917" @default.
- W1524514857 hasPublicationYear "2011" @default.
- W1524514857 type Work @default.
- W1524514857 sameAs 1524514857 @default.
- W1524514857 citedByCount "4" @default.
- W1524514857 countsByYear W15245148572013 @default.
- W1524514857 countsByYear W15245148572019 @default.
- W1524514857 crossrefType "journal-article" @default.
- W1524514857 hasAuthorship W1524514857A5012917073 @default.
- W1524514857 hasAuthorship W1524514857A5032042230 @default.
- W1524514857 hasAuthorship W1524514857A5071350449 @default.
- W1524514857 hasAuthorship W1524514857A5074439251 @default.
- W1524514857 hasAuthorship W1524514857A5076377253 @default.
- W1524514857 hasConcept C121608353 @default.
- W1524514857 hasConcept C126322002 @default.
- W1524514857 hasConcept C126894567 @default.
- W1524514857 hasConcept C2776235491 @default.
- W1524514857 hasConcept C2777562237 @default.
- W1524514857 hasConcept C2779466945 @default.
- W1524514857 hasConcept C2780192828 @default.
- W1524514857 hasConcept C2781406297 @default.
- W1524514857 hasConcept C2908647359 @default.
- W1524514857 hasConcept C3020110884 @default.
- W1524514857 hasConcept C46762472 @default.
- W1524514857 hasConcept C71924100 @default.
- W1524514857 hasConcept C90924648 @default.
- W1524514857 hasConcept C99454951 @default.
- W1524514857 hasConceptScore W1524514857C121608353 @default.
- W1524514857 hasConceptScore W1524514857C126322002 @default.
- W1524514857 hasConceptScore W1524514857C126894567 @default.
- W1524514857 hasConceptScore W1524514857C2776235491 @default.
- W1524514857 hasConceptScore W1524514857C2777562237 @default.
- W1524514857 hasConceptScore W1524514857C2779466945 @default.
- W1524514857 hasConceptScore W1524514857C2780192828 @default.
- W1524514857 hasConceptScore W1524514857C2781406297 @default.
- W1524514857 hasConceptScore W1524514857C2908647359 @default.
- W1524514857 hasConceptScore W1524514857C3020110884 @default.
- W1524514857 hasConceptScore W1524514857C46762472 @default.
- W1524514857 hasConceptScore W1524514857C71924100 @default.
- W1524514857 hasConceptScore W1524514857C90924648 @default.
- W1524514857 hasConceptScore W1524514857C99454951 @default.
- W1524514857 hasIssue "10" @default.
- W1524514857 hasLocation W15245148571 @default.
- W1524514857 hasOpenAccess W1524514857 @default.
- W1524514857 hasPrimaryLocation W15245148571 @default.
- W1524514857 hasRelatedWork W1979955543 @default.
- W1524514857 hasRelatedWork W1982816235 @default.
- W1524514857 hasRelatedWork W1989730849 @default.
- W1524514857 hasRelatedWork W2002000959 @default.
- W1524514857 hasRelatedWork W2060445317 @default.
- W1524514857 hasRelatedWork W2088630346 @default.
- W1524514857 hasRelatedWork W2283498514 @default.
- W1524514857 hasRelatedWork W3014716101 @default.
- W1524514857 hasRelatedWork W3038030631 @default.
- W1524514857 hasRelatedWork W93186087 @default.
- W1524514857 hasVolume "32" @default.
- W1524514857 isParatext "false" @default.
- W1524514857 isRetracted "false" @default.