FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1524551107> ?p ?o ?g. }

• W1524551107 endingPage "2903" @default.
• W1524551107 startingPage "2893" @default.
• W1524551107 abstract "Recombinant Epstein-Barr viruses with a stop codon inserted into the nuclear protein 3B (EBNA 3B) open reading frame were generated by second-site homologous recombination. These mutant viruses infected and growth transformed primary B lymphocytes, resulting in the establishment of lymphoblastoid cell lines (LCLs). Polymerase chain reaction analysis and Southern hybridizations with infected cell DNA demonstrated the presence of the mutant EBNA 3B and the absence of wild-type EBNA 3B. Immunoblot analysis of the LCLs with affinity-purified EBNA 3B antibodies confirmed the absence of EBNA 3B cross-reactive protein. Virus was reactivated from two of these infected LCLs and serially passaged through primary B lymphocytes. The newly infected cells contained only the mutant recombinant virus. No difference was noted between mutant and wild-type recombinants, derived in parallel, in latent (other than EBNA 3B) or lytic cycle-infected cell virus protein expression or in the growth of the latently infected transformed cell lines. These data indicate that the EBNA 3B protein is not critical for primary B-lymphocyte infection, growth transformation, or lytic virus infection in vitro." @default.
• W1524551107 created "2016-06-24" @default.
• W1524551107 creator A5049130593 @default.
• W1524551107 creator A5083595442 @default.
• W1524551107 date "1992-05-01" @default.
• W1524551107 modified "2023-10-17" @default.
• W1524551107 title "Use of second-site homologous recombination to demonstrate that Epstein-Barr virus nuclear protein 3B is not important for lymphocyte infection or growth transformation in vitro" @default.
• W1524551107 cites W1487658612 @default.
• W1524551107 cites W1511764016 @default.
• W1524551107 cites W1546570611 @default.
• W1524551107 cites W1560589415 @default.
• W1524551107 cites W1598586133 @default.
• W1524551107 cites W1599457281 @default.
• W1524551107 cites W1619023374 @default.
• W1524551107 cites W1696370831 @default.
• W1524551107 cites W1706373226 @default.
• W1524551107 cites W1752209517 @default.
• W1524551107 cites W1822723049 @default.
• W1524551107 cites W1829111599 @default.
• W1524551107 cites W1839972612 @default.
• W1524551107 cites W1844848296 @default.
• W1524551107 cites W1905217533 @default.
• W1524551107 cites W1910787045 @default.
• W1524551107 cites W1912140146 @default.
• W1524551107 cites W1937139132 @default.
• W1524551107 cites W1946498671 @default.
• W1524551107 cites W1950367760 @default.
• W1524551107 cites W1965041408 @default.
• W1524551107 cites W1978740438 @default.
• W1524551107 cites W1980464074 @default.
• W1524551107 cites W1983688171 @default.
• W1524551107 cites W1985082049 @default.
• W1524551107 cites W1985148567 @default.
• W1524551107 cites W1985695357 @default.
• W1524551107 cites W1990774063 @default.
• W1524551107 cites W1995701262 @default.
• W1524551107 cites W2003569705 @default.
• W1524551107 cites W2014520833 @default.
• W1524551107 cites W2015086018 @default.
• W1524551107 cites W2020828649 @default.
• W1524551107 cites W2021464282 @default.
• W1524551107 cites W2042644587 @default.
• W1524551107 cites W2071964308 @default.
• W1524551107 cites W2077210975 @default.
• W1524551107 cites W2079910001 @default.
• W1524551107 cites W2080249344 @default.
• W1524551107 cites W2082678443 @default.
• W1524551107 cites W2090657599 @default.
• W1524551107 cites W2092599452 @default.
• W1524551107 cites W2099390806 @default.
• W1524551107 cites W2119231028 @default.
• W1524551107 cites W2126784935 @default.
• W1524551107 cites W2130694207 @default.
• W1524551107 cites W2138270253 @default.
• W1524551107 cites W2145060532 @default.
• W1524551107 cites W2150650084 @default.
• W1524551107 cites W2151283814 @default.
• W1524551107 cites W2152827395 @default.
• W1524551107 cites W2154367621 @default.
• W1524551107 cites W2158208469 @default.
• W1524551107 cites W2167643299 @default.
• W1524551107 cites W2402730709 @default.
• W1524551107 cites W341470327 @default.
• W1524551107 cites W92147575 @default.
• W1524551107 cites W1877639507 @default.
• W1524551107 doi "https://doi.org/10.1128/jvi.66.5.2893-2903.1992" @default.
• W1524551107 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/241048" @default.
• W1524551107 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1313908" @default.
• W1524551107 hasPublicationYear "1992" @default.
• W1524551107 type Work @default.
• W1524551107 sameAs 1524551107 @default.
• W1524551107 citedByCount "124" @default.
• W1524551107 countsByYear W15245511072012 @default.
• W1524551107 countsByYear W15245511072013 @default.
• W1524551107 countsByYear W15245511072014 @default.
• W1524551107 countsByYear W15245511072015 @default.
• W1524551107 countsByYear W15245511072016 @default.
• W1524551107 countsByYear W15245511072017 @default.
• W1524551107 countsByYear W15245511072018 @default.
• W1524551107 countsByYear W15245511072019 @default.
• W1524551107 crossrefType "journal-article" @default.
• W1524551107 hasAuthorship W1524551107A5049130593 @default.
• W1524551107 hasAuthorship W1524551107A5083595442 @default.
• W1524551107 hasBestOaLocation W15245511071 @default.
• W1524551107 hasConcept C102744134 @default.
• W1524551107 hasConcept C104317684 @default.
• W1524551107 hasConcept C143065580 @default.
• W1524551107 hasConcept C153911025 @default.
• W1524551107 hasConcept C159047783 @default.
• W1524551107 hasConcept C182615771 @default.
• W1524551107 hasConcept C2522874641 @default.
• W1524551107 hasConcept C2781375147 @default.
• W1524551107 hasConcept C40767141 @default.
• W1524551107 hasConcept C54355233 @default.
• W1524551107 hasConcept C552990157 @default.
• W1524551107 hasConcept C86803240 @default.
• W1524551107 hasConceptScore W1524551107C102744134 @default.
• W1524551107 hasConceptScore W1524551107C104317684 @default.

• next