FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1524567035> ?p ?o ?g. }

• W1524567035 endingPage "11280" @default.
• W1524567035 startingPage "11274" @default.
• W1524567035 abstract "We have cloned, mapped and sequenced the complete CDC14 gene of Saccharomyces cerevisiae and characterized its transcription during the cell cycle. CDC14 was found within a 3.5-kilobase pair XhoI-XbaI fragment of chromosome VI. The DNA sequence reveals an open reading frame capable of encoding a 423-amino acid polypeptide. Protein sequence comparisons through the Prosite, GenBank and EMBL databases allowed us to identify a conserved protein tyrosine phosphatase active site in the encoded CDC14 protein beginning at amino acid 153. Disruption demonstrates that CDC14 is an essential gene. The level of the CDC14 transcript appears to be weakly cell cycle-regulated and has a periodicity which lags approximately 15 min behind histone HTB1 mRNA accumulation levels. DNA sequence analysis has identified a region within the CDC14 promoter which bears a striking resemblance (15 out of 21 base pairs identity) to the cell cycle regulation region of the promoter of the histone H2A1-H2B1 (HTA1-HTB1) gene pair. The cell cycle regulation sequence is responsible for the periodic accumulation and hydroxyurea sensitivity of the histone HTA1-HTB1 message. However, unlike histone mRNA, which is repressed upon hydroxyurea arrest, CDC14 mRNA appears to be unaffected. This suggests that CDC14 and histone genes are regulated by different mechanisms during the cell cycle. Furthermore, superhelical density measurements suggest that CDC14 is not involved in nucleosome assembly." @default.
• W1524567035 created "2016-06-24" @default.
• W1524567035 creator A5060014685 @default.
• W1524567035 creator A5064684441 @default.
• W1524567035 creator A5079062135 @default.
• W1524567035 date "1992-06-01" @default.
• W1524567035 modified "2023-10-10" @default.
• W1524567035 title "CDC14 of Saccharomyces cerevisiae. Cloning, sequence analysis, and transcription during the cell cycle." @default.
• W1524567035 cites W136427227 @default.
• W1524567035 cites W1487925028 @default.
• W1524567035 cites W1606923005 @default.
• W1524567035 cites W1941090429 @default.
• W1524567035 cites W2003569868 @default.
• W1524567035 cites W2015292449 @default.
• W1524567035 cites W2049488119 @default.
• W1524567035 cites W2060096281 @default.
• W1524567035 cites W2070670291 @default.
• W1524567035 cites W2074276122 @default.
• W1524567035 cites W2074838372 @default.
• W1524567035 cites W2076725137 @default.
• W1524567035 cites W2080895949 @default.
• W1524567035 cites W2085634797 @default.
• W1524567035 cites W2086605270 @default.
• W1524567035 cites W2100869677 @default.
• W1524567035 cites W2109829281 @default.
• W1524567035 cites W2121562033 @default.
• W1524567035 cites W2138476602 @default.
• W1524567035 cites W2152601156 @default.
• W1524567035 cites W2156920104 @default.
• W1524567035 cites W2159137674 @default.
• W1524567035 cites W2169333620 @default.
• W1524567035 cites W2172574870 @default.
• W1524567035 cites W2188548307 @default.
• W1524567035 cites W2296824236 @default.
• W1524567035 cites W4247074653 @default.
• W1524567035 doi "https://doi.org/10.1016/s0021-9258(19)49907-9" @default.
• W1524567035 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1597462" @default.
• W1524567035 hasPublicationYear "1992" @default.
• W1524567035 type Work @default.
• W1524567035 sameAs 1524567035 @default.
• W1524567035 citedByCount "88" @default.
• W1524567035 countsByYear W15245670352012 @default.
• W1524567035 countsByYear W15245670352015 @default.
• W1524567035 countsByYear W15245670352017 @default.
• W1524567035 countsByYear W15245670352023 @default.
• W1524567035 crossrefType "journal-article" @default.
• W1524567035 hasAuthorship W1524567035A5060014685 @default.
• W1524567035 hasAuthorship W1524567035A5064684441 @default.
• W1524567035 hasAuthorship W1524567035A5079062135 @default.
• W1524567035 hasBestOaLocation W15245670351 @default.
• W1524567035 hasConcept C121050878 @default.
• W1524567035 hasConcept C138885662 @default.
• W1524567035 hasConcept C1491633281 @default.
• W1524567035 hasConcept C179926584 @default.
• W1524567035 hasConcept C199360897 @default.
• W1524567035 hasConcept C2777576037 @default.
• W1524567035 hasConcept C2778112365 @default.
• W1524567035 hasConcept C2779222958 @default.
• W1524567035 hasConcept C29537977 @default.
• W1524567035 hasConcept C41008148 @default.
• W1524567035 hasConcept C41895202 @default.
• W1524567035 hasConcept C54355233 @default.
• W1524567035 hasConcept C70721500 @default.
• W1524567035 hasConcept C86803240 @default.
• W1524567035 hasConcept C95444343 @default.
• W1524567035 hasConceptScore W1524567035C121050878 @default.
• W1524567035 hasConceptScore W1524567035C138885662 @default.
• W1524567035 hasConceptScore W1524567035C1491633281 @default.
• W1524567035 hasConceptScore W1524567035C179926584 @default.
• W1524567035 hasConceptScore W1524567035C199360897 @default.
• W1524567035 hasConceptScore W1524567035C2777576037 @default.
• W1524567035 hasConceptScore W1524567035C2778112365 @default.
• W1524567035 hasConceptScore W1524567035C2779222958 @default.
• W1524567035 hasConceptScore W1524567035C29537977 @default.
• W1524567035 hasConceptScore W1524567035C41008148 @default.
• W1524567035 hasConceptScore W1524567035C41895202 @default.
• W1524567035 hasConceptScore W1524567035C54355233 @default.
• W1524567035 hasConceptScore W1524567035C70721500 @default.
• W1524567035 hasConceptScore W1524567035C86803240 @default.
• W1524567035 hasConceptScore W1524567035C95444343 @default.
• W1524567035 hasIssue "16" @default.
• W1524567035 hasLocation W15245670351 @default.
• W1524567035 hasOpenAccess W1524567035 @default.
• W1524567035 hasPrimaryLocation W15245670351 @default.
• W1524567035 hasRelatedWork W1509801266 @default.
• W1524567035 hasRelatedWork W1516770101 @default.
• W1524567035 hasRelatedWork W1897466773 @default.
• W1524567035 hasRelatedWork W2357011584 @default.
• W1524567035 hasRelatedWork W2623087137 @default.
• W1524567035 hasRelatedWork W3085090520 @default.
• W1524567035 hasRelatedWork W3200271510 @default.
• W1524567035 hasRelatedWork W4315558101 @default.
• W1524567035 hasRelatedWork W4380882399 @default.
• W1524567035 hasRelatedWork W63366483 @default.
• W1524567035 hasVolume "267" @default.
• W1524567035 isParatext "false" @default.
• W1524567035 isRetracted "false" @default.
• W1524567035 magId "1524567035" @default.

• next