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- W1525626881 abstract "Hypoxic-ischemic encephalopathy (HIE) is a clinical syndrome typically described in newborns after a period of intrapartum or perinatal hypoxia-ischemia (HI) [1]. The acute neurological manifestations of HIE have been well described [1,2] and are characterized by clinical evidence of diffuse cerebral dysfunction; impaired brainstem function, autonomic dysregulation, various abnormalities in mental state, epileptic seizures, and, in addition to tone and other motor abnormalities, non-epileptic movements i.e. myoclonus and tremors. The severity of the phenotype is dependent on the degree of cerebral insult, extent of subsequent injury incurred; with some correlation with outcome [1–4]. Because of the wide variety and often changing signs and symptoms post HI, coupled with the numerous co-morbid metabolic and systemic problems and the frequent occurrence of seizures which can be very difficult to differentiate clinically, this article will concentrate solely on describing the hyperkinetic non-epileptic movement disorder observed following transient HI in the term newborn." @default.
- W1525626881 created "2016-06-24" @default.
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- W1525626881 date "2015-07-30" @default.
- W1525626881 modified "2023-09-25" @default.
- W1525626881 title "Non-epileptic phenomena in hypoxic-ischemic encephalopathy" @default.
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- W1525626881 doi "https://doi.org/10.3233/jpn-2010-0360" @default.
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