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- W1526173672 abstract "The /sup 117m/Sn(4+)DTPA has been shown to have high uptake in cortical bone with negligible soft-tissue deposition. The long half-life (14 d) of /sup 117m/Sn and its emission of abundant short-range Auger and conversion electrons, make /sup 117m/Sn(4+)DTPA an attractive therapeutic agent for bone tumors. The necessary nuclear data for production of clinical quantities of /sup 117m/Sn using Sb(p,2pxn) reactions at BLIP was obtained. The excitation functions for /sup 121/Sb(p,2p3n) and /sup 123/Sb(p,2p5n) reactions in the regions of 43 less than or equal to E/sub p/ less than or equal to 60 MeV were measured and compared with predicted values obtained from semi-empirical formulae given by Silberberg and Tsao. /sup 117m/Sn is routinely produced at ORNL by thermal neutron activation of /sup 116/Sn. We have investigated the possibility of improving the specific activity of the reactor-produced /sup 117m/Sn by irradiating enriched /sup 116/Sn and /sup 117/Sn in the core of the HFBR. Our results indicate that, due to a strong absorption resonance at E/sub n/ approx. = 110 eV, better specific activity for reactor-produced /sup 117m/Sn can be obtained by irradiating natural tin in the core of a reactor. 7 refs., 1 fig. 1 tab." @default.
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- W1526173672 date "1985-01-01" @default.
- W1526173672 modified "2023-09-28" @default.
- W1526173672 title "Nuclear data for production of /sup 117m/Sn for biomedical application" @default.
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