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- W1526751605 abstract "EDG-3 is a receptor for sphingosine-1-phosphate mapped on human chromosome 9q22.1-q22.2. We used the compact Fugu genome for its linkage analysis. The Fugu EDG-3 was composed of one intron and two exons, encoding a 384 amino acid protein that has 56.9% homology with the human EDG-3. Approximately 3 kb apart, a neuronal Shc (N-Shc) gene was identified. It spans 7 kb containing 12 coding exons, and has an overall 53.4% similarity with the human protein. We mapped the human N-Shc gene to chromosome 9q21.3-q22.2. This is the first report of the genomic structure and the linkage of these two genes conserved between Fugu and human." @default.
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- W1526751605 date "1999-09-27" @default.
- W1526751605 modified "2023-09-23" @default.
- W1526751605 title "Molecular cloning of EDG-3 and N-Shc genes from the puffer fish,Fugu rubripes, and conservation of synteny with the human genome" @default.
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- W1526751605 doi "https://doi.org/10.1016/s0014-5793(99)01210-7" @default.
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