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- W1526905953 abstract "Abstract The pattern of the thyroidal radioiodine uptake, the nature of thyroid hormones in the thyroid gland and in the blood, and the in vitro study of the release and synthesis of iodinated substances by the thyroid gland in Elaphe were examined. The pattern of thyroidal 125 I accumulation in Elaphe was similar to that of the other ophidian species, e.g., Thamnophis and Natrix , in which there was a fairly rapid uptake of 125 I during the first week following the injection of 125 I; a gradual decrease in the rate followed in weeks 2 and 3, and an eventual levelling-off of the thyroidal 125 I radioactivity occurred. 125 I-Labelled MIT, DIT, T 3 , and T 4 were found in the thyroid gland 5 days after an ip injection of 125 I; at this time, however no labelled iodoamino acids were detected in the blood. 125 I-Labelled MIT, DIT, and T 4 were present in the circulation when measurements were made 12 days after injection of the radioiodine, and there was no appreciable change in the relative concentration of these iodoamino acids within 35 days. In vitro incubation studies of (a) a thyroid gland in the presence of 125 I and (b) a thyroid gland which had been 125 I-labelled for 5 days indicated that within a few hours 125 I-labelled iodotyrosines were formed, and that release of MIT, DIT, and T 4 began. The possible involvement of TSH in these aspects of radioiodime metabolism in the snake thyroid gland is discussed." @default.
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- W1526905953 date "1974-05-01" @default.
- W1526905953 modified "2023-10-18" @default.
- W1526905953 title "The snake thyroid gland" @default.
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- W1526905953 doi "https://doi.org/10.1016/0016-6480(74)90055-0" @default.
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