Matches in SemOpenAlex for { <https://semopenalex.org/work/W1527353170> ?p ?o ?g. }
- W1527353170 endingPage "318" @default.
- W1527353170 startingPage "311" @default.
- W1527353170 abstract "Abstract Recent studies imply the importance of rapid and reliable diagnostic assessment of 1p/19q status in oligodendroglial tumors. To date, fluorescence in situ hybridization ( FISH ) is the most commonly applied technique. FISH , however, has several technical shortcomings that are suboptimal for diagnostic applications: results must be viewed in a fluorescence microscope, results are usually evaluated by a single investigator only, and signal fading excludes physical archiving. Also, in gliomas, the distinction of diffusely infiltrating tumor cells from reactively altered normal tissue may be challenging in fluorescence microscopy. Dual‐color chromogenic in situ hybridization ( CISH ) has started to replace FISH in some diagnostic tests performed in pathology. Here, we present the first single institute experience with a side‐by‐side analysis of 1p/19q FISH and CISH in a series of 42 consecutive gliomas. FISH and CISH produced identical results for 1p and 19q in 93% of cases (n = 39/42). Discrepant results were reevaluated by repeated FISH and a polymerase chain reaction ( PCR )‐based microsatellite marker analysis for loss of heterozygosity. Reevaluation confirmed CISH data in all three cases. We conclude that CISH is a reliable alternative in 1p/19q testing in paraffin‐embedded tissues likely to be more sensitive to detect 1p/19q status than FISH analysis." @default.
- W1527353170 created "2016-06-24" @default.
- W1527353170 creator A5002399180 @default.
- W1527353170 creator A5010036887 @default.
- W1527353170 creator A5025477516 @default.
- W1527353170 creator A5037553148 @default.
- W1527353170 creator A5039647180 @default.
- W1527353170 creator A5041531993 @default.
- W1527353170 creator A5052657395 @default.
- W1527353170 date "2012-11-29" @default.
- W1527353170 modified "2023-10-17" @default.
- W1527353170 title "Chromogenic<i>in situ</i>Hybridization is a Reliable Alternative to Fluorescence<i>in situ</i>Hybridization for Diagnostic Testing of 1p and 19q Loss in Paraffin-Embedded Gliomas" @default.
- W1527353170 cites W1552123405 @default.
- W1527353170 cites W1968466970 @default.
- W1527353170 cites W1971303876 @default.
- W1527353170 cites W1975816021 @default.
- W1527353170 cites W1978352548 @default.
- W1527353170 cites W1996046150 @default.
- W1527353170 cites W1998135863 @default.
- W1527353170 cites W2001493754 @default.
- W1527353170 cites W2007730190 @default.
- W1527353170 cites W2011507080 @default.
- W1527353170 cites W2012768021 @default.
- W1527353170 cites W2013346068 @default.
- W1527353170 cites W2016852049 @default.
- W1527353170 cites W2030964595 @default.
- W1527353170 cites W2033115202 @default.
- W1527353170 cites W2065933998 @default.
- W1527353170 cites W2079871857 @default.
- W1527353170 cites W2080781806 @default.
- W1527353170 cites W2083862793 @default.
- W1527353170 cites W2084711476 @default.
- W1527353170 cites W2086383099 @default.
- W1527353170 cites W2086787201 @default.
- W1527353170 cites W2088134908 @default.
- W1527353170 cites W2092029005 @default.
- W1527353170 cites W2097589013 @default.
- W1527353170 cites W2105526612 @default.
- W1527353170 cites W2106263538 @default.
- W1527353170 cites W2110858984 @default.
- W1527353170 cites W2115666244 @default.
- W1527353170 cites W2129768320 @default.
- W1527353170 cites W2133551355 @default.
- W1527353170 cites W2145247163 @default.
- W1527353170 cites W2146025176 @default.
- W1527353170 cites W2146989265 @default.
- W1527353170 cites W2155457011 @default.
- W1527353170 cites W2159623602 @default.
- W1527353170 cites W2160507620 @default.
- W1527353170 cites W2168298750 @default.
- W1527353170 cites W2315877465 @default.
- W1527353170 cites W2407285786 @default.
- W1527353170 cites W2113308446 @default.
- W1527353170 doi "https://doi.org/10.1111/bpa.12003" @default.
- W1527353170 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8029485" @default.
- W1527353170 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23107103" @default.
- W1527353170 hasPublicationYear "2012" @default.
- W1527353170 type Work @default.
- W1527353170 sameAs 1527353170 @default.
- W1527353170 citedByCount "21" @default.
- W1527353170 countsByYear W15273531702014 @default.
- W1527353170 countsByYear W15273531702015 @default.
- W1527353170 countsByYear W15273531702016 @default.
- W1527353170 countsByYear W15273531702017 @default.
- W1527353170 countsByYear W15273531702018 @default.
- W1527353170 countsByYear W15273531702019 @default.
- W1527353170 countsByYear W15273531702020 @default.
- W1527353170 countsByYear W15273531702021 @default.
- W1527353170 countsByYear W15273531702022 @default.
- W1527353170 countsByYear W15273531702023 @default.
- W1527353170 crossrefType "journal-article" @default.
- W1527353170 hasAuthorship W1527353170A5002399180 @default.
- W1527353170 hasAuthorship W1527353170A5010036887 @default.
- W1527353170 hasAuthorship W1527353170A5025477516 @default.
- W1527353170 hasAuthorship W1527353170A5037553148 @default.
- W1527353170 hasAuthorship W1527353170A5039647180 @default.
- W1527353170 hasAuthorship W1527353170A5041531993 @default.
- W1527353170 hasAuthorship W1527353170A5052657395 @default.
- W1527353170 hasBestOaLocation W15273531702 @default.
- W1527353170 hasConcept C104317684 @default.
- W1527353170 hasConcept C121313828 @default.
- W1527353170 hasConcept C128463046 @default.
- W1527353170 hasConcept C142724271 @default.
- W1527353170 hasConcept C143589142 @default.
- W1527353170 hasConcept C150194340 @default.
- W1527353170 hasConcept C178790620 @default.
- W1527353170 hasConcept C180754005 @default.
- W1527353170 hasConcept C185592680 @default.
- W1527353170 hasConcept C2776643354 @default.
- W1527353170 hasConcept C2777542201 @default.
- W1527353170 hasConcept C2777822432 @default.
- W1527353170 hasConcept C2909208804 @default.
- W1527353170 hasConcept C30481170 @default.
- W1527353170 hasConcept C43617362 @default.
- W1527353170 hasConcept C505870484 @default.
- W1527353170 hasConcept C54355233 @default.
- W1527353170 hasConcept C71924100 @default.
- W1527353170 hasConcept C81439078 @default.