FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1527431520> ?p ?o ?g. }

• W1527431520 endingPage "1052" @default.
• W1527431520 startingPage "1044" @default.
• W1527431520 abstract "Autophagy (or autophagocytosis) is an essential and precise control process by which cells degrade unnecessary or dysfunctional cellular components or organelles in the cytoplasm in response to nutrient depletion, exogenous pathogens, or other stimuli. This process results in the removal of damaged or surplus organelles and macromolecular complexes via a lysosome-dependent mechanism. Bovine viral diarrhea virus (BVDV) is a ssRNA virus of the Flaviviridae family (genus Pestivirus). BVDV infection results in major economic losses due to poor reproductive performance and poor calf performance in cattle herds. In our previous studies, we have shown that BVDV NADL infection significantly increases autophagy in MDBK cells. To further define the interactions between autophagy and BVDV infection, we investigated the effects of autophagy on the replication of BVDV NADL. The findings showed that autophagy was inhibited by treatment with 3-methyladenine (3-MA) or wortmannin and that the knockdown of LC3 and Beclin1 using lentivirus-mediated RNA interference (RNAi) suppressed BVDV NADL replication. In contrast, the findings showed the replication of BVDV NADL was significantly increased by treatment with the autophagy inducer rapamycin within 18 h post-infection (pi). However, the mRNA levels of BVDV NADL 5'UTRs showed a downward trend after 18 h pi, and this effect was reversed by chloroquine treatment. Therefore, we inferred that infection with BVDV NADL increases autophagy, which in turn favors BVDV NADL replication at early stages." @default.
• W1527431520 created "2016-06-24" @default.
• W1527431520 creator A5003759585 @default.
• W1527431520 creator A5014116346 @default.
• W1527431520 creator A5035086533 @default.
• W1527431520 creator A5038699958 @default.
• W1527431520 creator A5040848445 @default.
• W1527431520 creator A5050018283 @default.
• W1527431520 creator A5050220993 @default.
• W1527431520 creator A5065048479 @default.
• W1527431520 creator A5073163963 @default.
• W1527431520 date "2013-12-17" @default.
• W1527431520 modified "2023-10-18" @default.
• W1527431520 title "Autophagy during early stages contributes to bovine viral diarrhea virus replication in MDBK cells" @default.
• W1527431520 cites W1524967393 @default.
• W1527431520 cites W1555642586 @default.
• W1527431520 cites W1590680361 @default.
• W1527431520 cites W1617545988 @default.
• W1527431520 cites W1818313483 @default.
• W1527431520 cites W1975387938 @default.
• W1527431520 cites W1977767269 @default.
• W1527431520 cites W1978751572 @default.
• W1527431520 cites W1987077730 @default.
• W1527431520 cites W1993364469 @default.
• W1527431520 cites W1994602517 @default.
• W1527431520 cites W2012451546 @default.
• W1527431520 cites W2023012828 @default.
• W1527431520 cites W202319641 @default.
• W1527431520 cites W2045842167 @default.
• W1527431520 cites W2050165541 @default.
• W1527431520 cites W2055679875 @default.
• W1527431520 cites W2056133106 @default.
• W1527431520 cites W2060311418 @default.
• W1527431520 cites W2063323349 @default.
• W1527431520 cites W2073129612 @default.
• W1527431520 cites W2075741684 @default.
• W1527431520 cites W2076649068 @default.
• W1527431520 cites W2087920955 @default.
• W1527431520 cites W2096797068 @default.
• W1527431520 cites W2100466458 @default.
• W1527431520 cites W2101722758 @default.
• W1527431520 cites W2107277218 @default.
• W1527431520 cites W2122700485 @default.
• W1527431520 cites W2131089732 @default.
• W1527431520 cites W2138528391 @default.
• W1527431520 cites W2146932940 @default.
• W1527431520 cites W2155313245 @default.
• W1527431520 cites W2168079335 @default.
• W1527431520 cites W2256756668 @default.
• W1527431520 doi "https://doi.org/10.1002/jobm.201300750" @default.
• W1527431520 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24347372" @default.
• W1527431520 hasPublicationYear "2013" @default.
• W1527431520 type Work @default.
• W1527431520 sameAs 1527431520 @default.
• W1527431520 citedByCount "16" @default.
• W1527431520 countsByYear W15274315202014 @default.
• W1527431520 countsByYear W15274315202015 @default.
• W1527431520 countsByYear W15274315202016 @default.
• W1527431520 countsByYear W15274315202017 @default.
• W1527431520 countsByYear W15274315202018 @default.
• W1527431520 countsByYear W15274315202020 @default.
• W1527431520 countsByYear W15274315202021 @default.
• W1527431520 countsByYear W15274315202022 @default.
• W1527431520 countsByYear W15274315202023 @default.
• W1527431520 crossrefType "journal-article" @default.
• W1527431520 hasAuthorship W1527431520A5003759585 @default.
• W1527431520 hasAuthorship W1527431520A5014116346 @default.
• W1527431520 hasAuthorship W1527431520A5035086533 @default.
• W1527431520 hasAuthorship W1527431520A5038699958 @default.
• W1527431520 hasAuthorship W1527431520A5040848445 @default.
• W1527431520 hasAuthorship W1527431520A5050018283 @default.
• W1527431520 hasAuthorship W1527431520A5050220993 @default.
• W1527431520 hasAuthorship W1527431520A5065048479 @default.
• W1527431520 hasAuthorship W1527431520A5073163963 @default.
• W1527431520 hasConcept C140704245 @default.
• W1527431520 hasConcept C159047783 @default.
• W1527431520 hasConcept C173396325 @default.
• W1527431520 hasConcept C181199279 @default.
• W1527431520 hasConcept C190062978 @default.
• W1527431520 hasConcept C190283241 @default.
• W1527431520 hasConcept C203522944 @default.
• W1527431520 hasConcept C2522874641 @default.
• W1527431520 hasConcept C2777510210 @default.
• W1527431520 hasConcept C2778400998 @default.
• W1527431520 hasConcept C2779755945 @default.
• W1527431520 hasConcept C2780216420 @default.
• W1527431520 hasConcept C2780727368 @default.
• W1527431520 hasConcept C54355233 @default.
• W1527431520 hasConcept C55493867 @default.
• W1527431520 hasConcept C81885089 @default.
• W1527431520 hasConcept C86803240 @default.
• W1527431520 hasConcept C95444343 @default.
• W1527431520 hasConceptScore W1527431520C140704245 @default.
• W1527431520 hasConceptScore W1527431520C159047783 @default.
• W1527431520 hasConceptScore W1527431520C173396325 @default.
• W1527431520 hasConceptScore W1527431520C181199279 @default.
• W1527431520 hasConceptScore W1527431520C190062978 @default.
• W1527431520 hasConceptScore W1527431520C190283241 @default.

• next