Matches in SemOpenAlex for { <https://semopenalex.org/work/W1527658139> ?p ?o ?g. }
- W1527658139 endingPage "15702" @default.
- W1527658139 startingPage "15696" @default.
- W1527658139 abstract "The parameters of the reaction between a rat alveolar macrophage lectin (Mr = 180,000) and its ligands have been examined. The reaction is dependent on Ca2+ over the optimal pH range for binding. The apparent dissociation constant for fucosyl bovine serum albumin, the standard ligand used in these studies, is 1.4 X 10(-10) M. The ligand binding specificity was determined by measurement of the inhibition of binding of fucosyl bovine serum albumin by various glycoproteins and saccharides. D-Mannose, L-fucose, and N-acetyl-D-glucosamine were the most effective inhibitors, and D-galactose was much poorer. The equatorial hydroxyl groups on the C-3 and C-4 of the mannose ring are important in the lectin-ligand interaction, and the axial hydroxyl group on the C-2 contributes to a lesser extent. Immunocytological studies revealed that the lectin isolated from alveolar macrophages is widely distributed in other rat tissues. Hepatocytes are devoid of the lectin, but hepatic Kupffer cells and endothelial cells contain significant amounts. This was confirmed by isolation of the lectin from liver. Spleen and skeletal muscle also contain lectin, but much smaller amounts were found in brain, kidney, and heart muscle." @default.
- W1527658139 created "2016-06-24" @default.
- W1527658139 creator A5044243639 @default.
- W1527658139 creator A5059614033 @default.
- W1527658139 date "1986-11-01" @default.
- W1527658139 modified "2023-10-01" @default.
- W1527658139 title "The ligand binding specificity and tissue localization of a rat alveolar macrophage lectin." @default.
- W1527658139 cites W1264549095 @default.
- W1527658139 cites W1479720671 @default.
- W1527658139 cites W1499137085 @default.
- W1527658139 cites W1505531015 @default.
- W1527658139 cites W1520943440 @default.
- W1527658139 cites W1528557572 @default.
- W1527658139 cites W1539890124 @default.
- W1527658139 cites W1547427125 @default.
- W1527658139 cites W1547893088 @default.
- W1527658139 cites W1561078613 @default.
- W1527658139 cites W1564905326 @default.
- W1527658139 cites W1569794535 @default.
- W1527658139 cites W1571857346 @default.
- W1527658139 cites W1584870824 @default.
- W1527658139 cites W1658581991 @default.
- W1527658139 cites W1717442359 @default.
- W1527658139 cites W1862745872 @default.
- W1527658139 cites W1891062175 @default.
- W1527658139 cites W1893651774 @default.
- W1527658139 cites W1973430424 @default.
- W1527658139 cites W1978105709 @default.
- W1527658139 cites W1983649348 @default.
- W1527658139 cites W1991348330 @default.
- W1527658139 cites W2001167497 @default.
- W1527658139 cites W2004070580 @default.
- W1527658139 cites W2035268027 @default.
- W1527658139 cites W2054941870 @default.
- W1527658139 cites W2067808410 @default.
- W1527658139 cites W2080374410 @default.
- W1527658139 cites W2082497364 @default.
- W1527658139 cites W2086336057 @default.
- W1527658139 cites W2094360785 @default.
- W1527658139 cites W2100837269 @default.
- W1527658139 cites W2111817213 @default.
- W1527658139 cites W2119460480 @default.
- W1527658139 cites W2327734390 @default.
- W1527658139 cites W97203087 @default.
- W1527658139 cites W976721469 @default.
- W1527658139 doi "https://doi.org/10.1016/s0021-9258(18)66773-0" @default.
- W1527658139 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3536911" @default.
- W1527658139 hasPublicationYear "1986" @default.
- W1527658139 type Work @default.
- W1527658139 sameAs 1527658139 @default.
- W1527658139 citedByCount "54" @default.
- W1527658139 countsByYear W15276581392012 @default.
- W1527658139 countsByYear W15276581392013 @default.
- W1527658139 countsByYear W15276581392014 @default.
- W1527658139 countsByYear W15276581392015 @default.
- W1527658139 countsByYear W15276581392016 @default.
- W1527658139 countsByYear W15276581392017 @default.
- W1527658139 countsByYear W15276581392019 @default.
- W1527658139 crossrefType "journal-article" @default.
- W1527658139 hasAuthorship W1527658139A5044243639 @default.
- W1527658139 hasAuthorship W1527658139A5059614033 @default.
- W1527658139 hasBestOaLocation W15276581391 @default.
- W1527658139 hasConcept C116569031 @default.
- W1527658139 hasConcept C170493617 @default.
- W1527658139 hasConcept C185592680 @default.
- W1527658139 hasConcept C202751555 @default.
- W1527658139 hasConcept C2778012055 @default.
- W1527658139 hasConcept C2779244956 @default.
- W1527658139 hasConcept C2780758401 @default.
- W1527658139 hasConcept C55493867 @default.
- W1527658139 hasConcept C86803240 @default.
- W1527658139 hasConcept C95444343 @default.
- W1527658139 hasConceptScore W1527658139C116569031 @default.
- W1527658139 hasConceptScore W1527658139C170493617 @default.
- W1527658139 hasConceptScore W1527658139C185592680 @default.
- W1527658139 hasConceptScore W1527658139C202751555 @default.
- W1527658139 hasConceptScore W1527658139C2778012055 @default.
- W1527658139 hasConceptScore W1527658139C2779244956 @default.
- W1527658139 hasConceptScore W1527658139C2780758401 @default.
- W1527658139 hasConceptScore W1527658139C55493867 @default.
- W1527658139 hasConceptScore W1527658139C86803240 @default.
- W1527658139 hasConceptScore W1527658139C95444343 @default.
- W1527658139 hasIssue "33" @default.
- W1527658139 hasLocation W15276581391 @default.
- W1527658139 hasOpenAccess W1527658139 @default.
- W1527658139 hasPrimaryLocation W15276581391 @default.
- W1527658139 hasRelatedWork W1979957787 @default.
- W1527658139 hasRelatedWork W1980377213 @default.
- W1527658139 hasRelatedWork W2011802865 @default.
- W1527658139 hasRelatedWork W2050940716 @default.
- W1527658139 hasRelatedWork W2739417245 @default.
- W1527658139 hasRelatedWork W2917030074 @default.
- W1527658139 hasRelatedWork W2952991618 @default.
- W1527658139 hasRelatedWork W2967145957 @default.
- W1527658139 hasRelatedWork W4210541988 @default.
- W1527658139 hasRelatedWork W4230779809 @default.
- W1527658139 hasVolume "261" @default.
- W1527658139 isParatext "false" @default.