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- W1528363068 abstract "Publisher Summary This chapter discusses the genetic and biochemical analysis of Staphylococcus epidermidis accumulation. It is the most prominent coagulase-negative staphylococcal species that colonizes human skin and mucous membranes. It exhibits a low pathogenic potential in the normal human host. Coagulase-negative staphylococci ranks amongst the five most frequent causative organisms of nosocomial infections. The reason is a tremendous increase in the incidence of nosocomial sepsis and infections related to implanted foreign materials such as intravascular and peritoneal dialysis catheters, cerebrospinal fluid shunts, prosthetic heart valves and prosthetic joints, vascular grafts, cardiac pacemakers, and intraocular lenses. It is believed that the specific virulence of S. epidermidis in medical devicerelated infections is linked to an unusual ability to colonize polymer surfaces in multilayered biofilms. In vitro, a proportion of S. epidermidis strains produce a macroscopically visible, adherent biofilm on test tubes or tissue culture plates with morphology in scanning electron micrographs similar to that of infected intravascular catheters. Biofilm formation may be divided in two phases: primary attachment of staphylococcal cells to a polymer surface is a complex process involving various physicochemical factors; and the attached bacteria proliferate and accumulated in a multilayered biofilm." @default.
- W1528363068 created "2016-06-24" @default.
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- W1528363068 date "2001-01-01" @default.
- W1528363068 modified "2023-10-18" @default.
- W1528363068 title "[20] Genetic and biochemical analysis of Staphylococcus epidermidis biofilm accumulation" @default.
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- W1528363068 doi "https://doi.org/10.1016/s0076-6879(01)36592-8" @default.
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