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- W1528372603 abstract "Nous rapportons deux observations de lymphadénopathie dysimmunitaire avec aspect anatomopathologique de lymphadénopathie angio-immunoblastique (LAI) survenant au cours d'un traitement par la carbamazépine (Tégrétol*). Les deux malades présentaient une symptomatologie similaire: fièvre, érythrodermie, prurit, œdème de la face, polyadénopathie, hépatomégalie, anémie, élévation des enzymes hépatiques, hypogammaglobulinémie, test de Coombs négatif. Un test de transformation lymphoblastique était positif vis-à-vis de la carbamazépine dans les deux cas; l'histologie ganglionnaire révélait un aspect caractéristique de LAI. L'arrêt de la carbamazépine s'est accompagné de la rémission complète des symptômes. Dysimmune lymphadenopathies during carbamazepine treatment. A report of two cases. We report on two cases of dysimmune lymphadenopathies with histological aspect of angio immunoblastic lymphadenopathy (AIL) developing after administration of carbamazepine. Clinical manifestations consisted of fever, erythroderma, generalized pruritus, facial edema, lymphadenopathy, liver enlargement. The two patients had anemia, hypogammaglobulinemia, impaired liver function and a negative Coomb's test. Lymphocyte stimulation test with carbamazepine in vitro was positive in both cases. Lymph node biopsy disclosed the angioimmunoblastic proliferation characteristic of AIL. After discontinuing carbamazepine, a complete remission was obtained." @default.
- W1528372603 created "2016-06-24" @default.
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- W1528372603 date "1984-03-01" @default.
- W1528372603 modified "2023-10-01" @default.
- W1528372603 title "Lymphadénopathie dysimmunitaire survenant au cours d'un traitement par la carbamazépine" @default.
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- W1528372603 doi "https://doi.org/10.1016/s0248-8663(84)80083-1" @default.
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