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• W1528438515 abstract "Summary The aim of this study was to examine whether serum anticholinergic activity (SAA) is a reliable indicator of delirium in the ICU, and whether there is a significant correlation between SAA and quantitative electroencephalographic (EEG) data in delirious patients. In a prospective cohort study, we assessed ICU patients diagnosed with delirium ( n = 37). EEG measurements and blood analysis including SAA were performed 48 h following ICU admission. The presence of delirium was evaluated using the Confusion Assessment Method for critically ill patients in ICU (CAM‐ICU). The SAA level was measured using a competitive radioreceptor binding assay for muscarinergic receptors and quantitative EEG was measured using the CATEEM ® system. We found that, under comparable conditions, patients in the delirium group showed a higher relative EEG theta power and a reduced alpha power ( n = 17) than did the non‐delirious patients ( n = 20). No difference in measured SAA levels were seen; therefore, there was no correlation between SAA and EEG measurements in delirious patients. We conclude that, in contrast to the EEG, the SAA level cannot be proposed as a tool for diagnosing delirium in ICU patients." @default.
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• W1528438515 date "2007-11-05" @default.
• W1528438515 modified "2023-10-18" @default.
• W1528438515 title "EEG changes and serum anticholinergic activity measured in patients with delirium in the intensive care unit" @default.
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• W1528438515 doi "https://doi.org/10.1111/j.1365-2044.2007.05255.x" @default.
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