FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1528440096> ?p ?o ?g. }

• W1528440096 abstract "The different genomic environments in which transposable elements reside in the Great Apes and the Drosophila result in substantial differences between the evolution of transposable elements in these two groups of organisms. In the Great Apes, where deletion of transposable elements is relatively rare, elements tend to be retained in the genome to the extent that complete sets of elements belonging to a particular transposable element family can be obtained. In Drosophila, there is a rapid turnover of transposable elements, imposing strong selection pressure on transposable elements to be able to infect new hosts. This study investigates the evolution of transposable elements in these two genomic environments.Complete sets of elements belonging to young Alu subfamilies in humans and closely-related species are used to investigate factors involved in their evolutionary history, such as mutation and gene conversion. The application of the master gene model, and other proposed models of the proliferation of young Alu subfamilies, are considered in light of the results obtained. The evolution of the AluYg, Yh and Yi lineages are investigated using a C++ program to simulate their evolutionary history. The results of the simulations are compared to statistics such as theta and pi, as well as the number of shared mutations and the proliferation time, in order to determine possible, and likely, values for parameters such as the retrotransposition rate and the number of source elements for each subfamily. The results suggest that although the master gene model may apply to some lineages, it is not the best model to explain the evolutionary history of all young Alu subfamilies.The selection pressure on transposable elements in Drosophila results in a high level of horizontal transfer of these elements among species of the Drosophila genus. In this study, the twelve sequenced Drosophila genomes are used to investigate the frequency of horizontal transfer within these twelve species using a large dataset of transposable element sequences from the DNA transposons, as well as LTR, and non-LTR, retrotransposons. Horizontal transfer is inferred where identity between transposable elements of the same family in different species exceeds that between the coding regions of the Adh gene in the relevant species. Cases are further supported by evidence from the distribution of the transposable element family across the Drosophila genus, and phylogenetic incongruence, which in many cases elucidates likely directions of transfer. The results suggest that horizontal transfer may be even more common than previously thought, and appears to be most common for the LTR retrotransposons. The possibility that possession of the env gene may result in higher rates of horizontal transfer of LTR retrotransposons is investigated, and the env open reading frame is found to be under selective constraint." @default.
• W1528440096 created "2016-06-24" @default.
• W1528440096 creator A5056732043 @default.
• W1528440096 date "2010-07-15" @default.
• W1528440096 modified "2023-09-28" @default.
• W1528440096 title "The evolution of transposable elements in humans and Drosophila" @default.
• W1528440096 cites W143898729 @default.
• W1528440096 cites W1502326502 @default.
• W1528440096 cites W1550556638 @default.
• W1528440096 cites W1700791820 @default.
• W1528440096 cites W1705376011 @default.
• W1528440096 cites W1838926299 @default.
• W1528440096 cites W1860733958 @default.
• W1528440096 cites W1864025525 @default.
• W1528440096 cites W1965987622 @default.
• W1528440096 cites W1966080460 @default.
• W1528440096 cites W1967212943 @default.
• W1528440096 cites W1967386015 @default.
• W1528440096 cites W1970220390 @default.
• W1528440096 cites W1973886143 @default.
• W1528440096 cites W1975464415 @default.
• W1528440096 cites W1976198449 @default.
• W1528440096 cites W1976624218 @default.
• W1528440096 cites W1977369042 @default.
• W1528440096 cites W1979108548 @default.
• W1528440096 cites W1981404680 @default.
• W1528440096 cites W1987875612 @default.
• W1528440096 cites W1989942162 @default.
• W1528440096 cites W1990324919 @default.
• W1528440096 cites W1996086595 @default.
• W1528440096 cites W2001266010 @default.
• W1528440096 cites W2001266015 @default.
• W1528440096 cites W2004284284 @default.
• W1528440096 cites W2005686029 @default.
• W1528440096 cites W2006699168 @default.
• W1528440096 cites W2010310827 @default.
• W1528440096 cites W2011362085 @default.
• W1528440096 cites W2012008832 @default.
• W1528440096 cites W2013382620 @default.
• W1528440096 cites W2015290897 @default.
• W1528440096 cites W2015521887 @default.
• W1528440096 cites W2015820342 @default.
• W1528440096 cites W2018086201 @default.
• W1528440096 cites W2018112341 @default.
• W1528440096 cites W2019269201 @default.
• W1528440096 cites W2021299885 @default.
• W1528440096 cites W2021660928 @default.
• W1528440096 cites W2025729769 @default.
• W1528440096 cites W2026004154 @default.
• W1528440096 cites W2027119249 @default.
• W1528440096 cites W2027361898 @default.
• W1528440096 cites W2031301616 @default.
• W1528440096 cites W2032547380 @default.
• W1528440096 cites W2032621255 @default.
• W1528440096 cites W2034353459 @default.
• W1528440096 cites W2036234991 @default.
• W1528440096 cites W2036985139 @default.
• W1528440096 cites W2042081010 @default.
• W1528440096 cites W2043832653 @default.
• W1528440096 cites W2045227735 @default.
• W1528440096 cites W2047335170 @default.
• W1528440096 cites W2047853548 @default.
• W1528440096 cites W2050557699 @default.
• W1528440096 cites W2054745526 @default.
• W1528440096 cites W2055049195 @default.
• W1528440096 cites W2056668940 @default.
• W1528440096 cites W2057118867 @default.
• W1528440096 cites W2059366734 @default.
• W1528440096 cites W2059644280 @default.
• W1528440096 cites W2063620062 @default.
• W1528440096 cites W2068191543 @default.
• W1528440096 cites W2069247367 @default.
• W1528440096 cites W2070531171 @default.
• W1528440096 cites W2070797653 @default.
• W1528440096 cites W2071422117 @default.
• W1528440096 cites W2071501400 @default.
• W1528440096 cites W2072204610 @default.
• W1528440096 cites W2072991611 @default.
• W1528440096 cites W2074813718 @default.
• W1528440096 cites W2075168304 @default.
• W1528440096 cites W2075586130 @default.
• W1528440096 cites W2077879161 @default.
• W1528440096 cites W2080458946 @default.
• W1528440096 cites W2082807451 @default.
• W1528440096 cites W2083224050 @default.
• W1528440096 cites W2085708372 @default.
• W1528440096 cites W2085747761 @default.
• W1528440096 cites W2086739233 @default.
• W1528440096 cites W2089465591 @default.
• W1528440096 cites W2089988218 @default.
• W1528440096 cites W2090631790 @default.
• W1528440096 cites W2092476162 @default.
• W1528440096 cites W2093045629 @default.
• W1528440096 cites W2094079639 @default.
• W1528440096 cites W2094592896 @default.
• W1528440096 cites W2095724872 @default.
• W1528440096 cites W2098274473 @default.
• W1528440096 cites W2099762535 @default.
• W1528440096 cites W2102234847 @default.
• W1528440096 cites W2104789942 @default.

• next