FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1528668873> ?p ?o ?g. }

• W1528668873 endingPage "3765" @default.
• W1528668873 startingPage "3758" @default.
• W1528668873 abstract "BACKGROUND: Patients with large, high-grade, extremity soft tissue sarcomas (STS) are at significant risk for distant recurrence and death. A regimen of preoperative chemotherapy consisting of mesna, Adriamycin (doxorubicin), ifosfamide, and dacarbazine (MAID), interdigitated with radiotherapy (RT) and followed by resection and postoperative chemotherapy with or without RT, has demonstrated high rates of local and distant control. We report the long-term follow-up data on 48 patients treated with this regimen compared to an historical matched-control patient population. METHODS: Adult patients with high-grade extremity STS ≥ 8 cm were treated with 3 cycles of preoperative chemotherapy combined with 44 Gy of RT followed by surgery. Three cycles of postoperative MAID were planned. For patients with positive surgical margins, 16 Gy of RT was delivered postoperatively. RESULTS: Patients received the MAID/RT regimen from 1989 through 1999. After a median follow-up of 9.3 years in surviving patients in the MAID group and 13.2 years in surviving patients in the control group, the 7-year disease-specific and overall survival rates were 81% and 50% (P = .004) and 79% and 45% (P = .003) for the MAID and control patients, respectively. Five of 11 patients in the MAID group and 7 of 25 control patients died of sarcoma ≥5 years after treatment. One patient in the MAID group developed a fatal myelodysplasia at 53 months. CONCLUSIONS: For patients with high-risk, extremity STS, the significant survival benefits conferred by an intense regimen of neoadjuvant chemoradiotherapy and surgery are sustained even with long-term follow-up. Cancer 2012. © 2011 American Cancer Society." @default.
• W1528668873 created "2016-06-24" @default.
• W1528668873 creator A5017550859 @default.
• W1528668873 creator A5019950679 @default.
• W1528668873 creator A5024913801 @default.
• W1528668873 creator A5034485889 @default.
• W1528668873 creator A5035395158 @default.
• W1528668873 creator A5038077156 @default.
• W1528668873 creator A5045223280 @default.
• W1528668873 creator A5045674674 @default.
• W1528668873 creator A5059709353 @default.
• W1528668873 creator A5071532449 @default.
• W1528668873 date "2011-12-16" @default.
• W1528668873 modified "2023-10-13" @default.
• W1528668873 title "Long-term follow-up of patients treated with neoadjuvant chemotherapy and radiotherapy for large, extremity soft tissue sarcomas" @default.
• W1528668873 cites W1878715328 @default.
• W1528668873 cites W1912227677 @default.
• W1528668873 cites W2050917665 @default.
• W1528668873 cites W2051346698 @default.
• W1528668873 cites W2059931397 @default.
• W1528668873 cites W2064558107 @default.
• W1528668873 cites W2067787818 @default.
• W1528668873 cites W2081613982 @default.
• W1528668873 cites W2096854366 @default.
• W1528668873 cites W2100339026 @default.
• W1528668873 cites W2119535651 @default.
• W1528668873 cites W2137714866 @default.
• W1528668873 cites W2147255274 @default.
• W1528668873 cites W2263318751 @default.
• W1528668873 cites W2275599683 @default.
• W1528668873 cites W4293241248 @default.
• W1528668873 doi "https://doi.org/10.1002/cncr.26696" @default.
• W1528668873 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22180344" @default.
• W1528668873 hasPublicationYear "2011" @default.
• W1528668873 type Work @default.
• W1528668873 sameAs 1528668873 @default.
• W1528668873 citedByCount "78" @default.
• W1528668873 countsByYear W15286688732012 @default.
• W1528668873 countsByYear W15286688732013 @default.
• W1528668873 countsByYear W15286688732014 @default.
• W1528668873 countsByYear W15286688732015 @default.
• W1528668873 countsByYear W15286688732016 @default.
• W1528668873 countsByYear W15286688732017 @default.
• W1528668873 countsByYear W15286688732018 @default.
• W1528668873 countsByYear W15286688732019 @default.
• W1528668873 countsByYear W15286688732020 @default.
• W1528668873 countsByYear W15286688732021 @default.
• W1528668873 countsByYear W15286688732022 @default.
• W1528668873 countsByYear W15286688732023 @default.
• W1528668873 crossrefType "journal-article" @default.
• W1528668873 hasAuthorship W1528668873A5017550859 @default.
• W1528668873 hasAuthorship W1528668873A5019950679 @default.
• W1528668873 hasAuthorship W1528668873A5024913801 @default.
• W1528668873 hasAuthorship W1528668873A5034485889 @default.
• W1528668873 hasAuthorship W1528668873A5035395158 @default.
• W1528668873 hasAuthorship W1528668873A5038077156 @default.
• W1528668873 hasAuthorship W1528668873A5045223280 @default.
• W1528668873 hasAuthorship W1528668873A5045674674 @default.
• W1528668873 hasAuthorship W1528668873A5059709353 @default.
• W1528668873 hasAuthorship W1528668873A5071532449 @default.
• W1528668873 hasBestOaLocation W15286688731 @default.
• W1528668873 hasConcept C136948725 @default.
• W1528668873 hasConcept C141071460 @default.
• W1528668873 hasConcept C142724271 @default.
• W1528668873 hasConcept C2776694085 @default.
• W1528668873 hasConcept C2777506904 @default.
• W1528668873 hasConcept C2778239845 @default.
• W1528668873 hasConcept C2778256501 @default.
• W1528668873 hasConcept C2778336483 @default.
• W1528668873 hasConcept C2778424827 @default.
• W1528668873 hasConcept C2778629024 @default.
• W1528668873 hasConcept C2780376820 @default.
• W1528668873 hasConcept C2780964509 @default.
• W1528668873 hasConcept C2781413609 @default.
• W1528668873 hasConcept C509974204 @default.
• W1528668873 hasConcept C71924100 @default.
• W1528668873 hasConceptScore W1528668873C136948725 @default.
• W1528668873 hasConceptScore W1528668873C141071460 @default.
• W1528668873 hasConceptScore W1528668873C142724271 @default.
• W1528668873 hasConceptScore W1528668873C2776694085 @default.
• W1528668873 hasConceptScore W1528668873C2777506904 @default.
• W1528668873 hasConceptScore W1528668873C2778239845 @default.
• W1528668873 hasConceptScore W1528668873C2778256501 @default.
• W1528668873 hasConceptScore W1528668873C2778336483 @default.
• W1528668873 hasConceptScore W1528668873C2778424827 @default.
• W1528668873 hasConceptScore W1528668873C2778629024 @default.
• W1528668873 hasConceptScore W1528668873C2780376820 @default.
• W1528668873 hasConceptScore W1528668873C2780964509 @default.
• W1528668873 hasConceptScore W1528668873C2781413609 @default.
• W1528668873 hasConceptScore W1528668873C509974204 @default.
• W1528668873 hasConceptScore W1528668873C71924100 @default.
• W1528668873 hasIssue "15" @default.
• W1528668873 hasLocation W15286688731 @default.
• W1528668873 hasLocation W15286688732 @default.
• W1528668873 hasOpenAccess W1528668873 @default.
• W1528668873 hasPrimaryLocation W15286688731 @default.
• W1528668873 hasRelatedWork W16679105 @default.
• W1528668873 hasRelatedWork W173559088 @default.

• next