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• W1528686575 abstract "We propose that CD4+CD3− cells have two functions: a well-established role in organizing lymphoid tissue during development, and a newly discovered role in supporting T-cell help for B cells both during affinity maturation in germinal centres and for memory antibody responses. As CD4+CD3− cells express the HIV co-receptors CD4 and CXC-chemokine receptor 4, we think that infection of these cells by HIV, and their subsequent destruction by the host immune system, could help to explain the loss of memory antibody responses and the destruction of lymphoid architecture that occur during disease progression to AIDS." @default.
• W1528686575 created "2016-06-24" @default.
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• W1528686575 date "2005-07-20" @default.
• W1528686575 modified "2023-09-27" @default.
• W1528686575 title "Two sides of a cellular coin: CD4+CD3− cells regulate memory responses and lymph-node organization" @default.
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• W1528686575 doi "https://doi.org/10.1038/nri1665" @default.
• W1528686575 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1351344" @default.
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