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• W1528857529 abstract "Three series of isatin derivatives [3-hydrazino, 3-thiosemicarbazino, and 3-imino carboxylic acid derivatives] were synthesized employing microwave irradiation. The prepared compounds were characterized by FT-IR, NMR, elemental analysis, and X-ray crystallography for derivatives 5b . The synthesized compounds were screened for antimicrobial activity against selected bacteria and fungi. The results revealed that the N -alkyl isatin derivatives were biologically active with different spectrums activity. Most of the 3-hydrazino and 3-thiosemicarbazino isatin derivatives were biologically inactive and generally the active derivatives showed weak to moderate activity mainly against Gram-positive bacteria. The imino isatin carboxylic acid derivatives (2-[4-(1-benzyl-5-bromo-2-oxoindolin-3-ylideneamino) phenyl]acetic acid, 5d ) showed promising activity against all tested Gram-positive bacteria and against fungal pathogens." @default.
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• W1528857529 date "2015-01-01" @default.
• W1528857529 modified "2023-10-17" @default.
• W1528857529 title "Microwave Synthesis, Characterization, and Antimicrobial Activity of Some Novel Isatin Derivatives" @default.
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• W1528857529 doi "https://doi.org/10.1155/2015/716987" @default.
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