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- W152927054 abstract "Oxidative damage to normal human brain tissue was induced following exposure to hydroxyl (OH.) or superoxide (O2-.) free radical species generated by CO60 irradiation in vitro. Both enzymic and cytoskeletal proteins showed substantial (dose dependent) oxidative damage following exposure to OH. or O2-., as quantified by SDS-polyacrylamide gel electrophoretic analysis. Extracts of Ginkgo biloba or Panax ginseng showed a remarkable capacity to protect brain tissue proteins from oxidative damage in vitro, even at extreme (2000 kRads) dosage levels of OH. or O2-.. We suggest, therefore, that the beneficial effect of these plant extracts in preventing brain tissue damage in vivo (e.g. following ischemia-reperfusion) may result from their action in protecting brain proteins from oxidative damage, in addition to their previously reported capacity to reduce free radical induced lipid peroxidation." @default.
- W152927054 created "2016-06-24" @default.
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- W152927054 date "2000-01-01" @default.
- W152927054 modified "2023-09-23" @default.
- W152927054 title "Extracts of Ginkgo Biloba and Panax Ginseng Protect Brain Proteins from Free Radical Induced Oxidative Damage in Vitro" @default.
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- W152927054 doi "https://doi.org/10.1007/978-3-7091-6346-7_18" @default.
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