FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1529289359> ?p ?o ?g. }

• W1529289359 endingPage "2417" @default.
• W1529289359 startingPage "2405" @default.
• W1529289359 abstract "The muscle pump and muscle vasodilatory mechanims are thought to play important roles in increasing and maintaining muscle perfusion and cardiac output during exercise, but their actual contributions remain uncertain. To evaluate the role of the skeletal muscle pump and vasodilatation on cardiovascular function during exercise, we determined leg and systemic haemodynamic responses in healthy men during (1) incremental one‐legged knee‐extensor exercise, (2) step‐wise femoral artery ATP infusion at rest, (3) passive exercise ( n = 10), (4) femoral vein or artery ATP infusion ( n = 6), and (5) cyclic thigh compressions at rest and during passive and voluntary exercise ( n = 7). Incremental exercise resulted in progressive increases in leg blood flow (ΔLBF 7.4 ± 0.7 l min −1 ), cardiac output ( 8.7 ± 0.7 l min −1 ), mean arterial pressure (ΔMAP 51 ± 5 mmHg), and leg and systemic oxygen delivery and . Arterial ATP infusion resulted in similar increases in , LBF, and systemic and leg oxygen delivery, but central venous pressure and muscle metabolism remained unchanged and MAP was reduced. In contrast, femoral vein ATP infusion did not alter LBF, or MAP. Passive exercise also increased blood flow (ΔLBF 0.7 ± 0.1 l min −1 ), yet the increase in muscle and systemic perfusion, unrelated to elevations in aerobic metabolism, accounted only for ∼5% of peak exercise hyperaemia. Likewise, thigh compressions alone or in combination with passive exercise increased blood flow (ΔLBF 0.5–0.7 l min −1 ) without altering , MAP or . These findings suggest that the skeletal muscle pump is not obligatory for sustaining venous return, central venous pressure, stroke volume and or maintaining muscle blood flow during one‐legged exercise in humans. Further, its contribution to muscle and systemic peak exercise hyperaemia appears to be minimal in comparison to the effects of muscle vasodilatation." @default.
• W1529289359 created "2016-06-24" @default.
• W1529289359 creator A5015138528 @default.
• W1529289359 creator A5017600752 @default.
• W1529289359 creator A5030369550 @default.
• W1529289359 creator A5048328154 @default.
• W1529289359 creator A5050361725 @default.
• W1529289359 creator A5059223836 @default.
• W1529289359 creator A5065648265 @default.
• W1529289359 creator A5078425072 @default.
• W1529289359 creator A5088621336 @default.
• W1529289359 date "2008-05-01" @default.
• W1529289359 modified "2023-10-15" @default.
• W1529289359 title "Haemodynamic responses to exercise, ATP infusion and thigh compression in humans: insight into the role of muscle mechanisms on cardiovascular function" @default.
• W1529289359 cites W1483990096 @default.
• W1529289359 cites W1491802876 @default.
• W1529289359 cites W1515794427 @default.
• W1529289359 cites W1520615434 @default.
• W1529289359 cites W1547712730 @default.
• W1529289359 cites W1578139176 @default.
• W1529289359 cites W1797533920 @default.
• W1529289359 cites W1965168499 @default.
• W1529289359 cites W1966262720 @default.
• W1529289359 cites W1968721184 @default.
• W1529289359 cites W1974809183 @default.
• W1529289359 cites W1978495288 @default.
• W1529289359 cites W1979071485 @default.
• W1529289359 cites W1984427077 @default.
• W1529289359 cites W1985705252 @default.
• W1529289359 cites W1985914857 @default.
• W1529289359 cites W1987270666 @default.
• W1529289359 cites W1995081070 @default.
• W1529289359 cites W1999884192 @default.
• W1529289359 cites W2015190898 @default.
• W1529289359 cites W2018746699 @default.
• W1529289359 cites W2028431787 @default.
• W1529289359 cites W2037585389 @default.
• W1529289359 cites W2038586113 @default.
• W1529289359 cites W2072372222 @default.
• W1529289359 cites W2074243670 @default.
• W1529289359 cites W2077210949 @default.
• W1529289359 cites W2083267508 @default.
• W1529289359 cites W2088192972 @default.
• W1529289359 cites W2095511577 @default.
• W1529289359 cites W2100449437 @default.
• W1529289359 cites W2113027422 @default.
• W1529289359 cites W2121467847 @default.
• W1529289359 cites W2121718757 @default.
• W1529289359 cites W2128724933 @default.
• W1529289359 cites W2144096901 @default.
• W1529289359 cites W2150096529 @default.
• W1529289359 cites W2156338853 @default.
• W1529289359 cites W2164552936 @default.
• W1529289359 cites W2164714615 @default.
• W1529289359 cites W2165389432 @default.
• W1529289359 cites W2172118895 @default.
• W1529289359 cites W2178990521 @default.
• W1529289359 cites W2196755532 @default.
• W1529289359 cites W2261542984 @default.
• W1529289359 cites W2336661543 @default.
• W1529289359 cites W4251025669 @default.
• W1529289359 cites W4251842375 @default.
• W1529289359 doi "https://doi.org/10.1113/jphysiol.2008.152058" @default.
• W1529289359 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2479567" @default.
• W1529289359 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18339690" @default.
• W1529289359 hasPublicationYear "2008" @default.
• W1529289359 type Work @default.
• W1529289359 sameAs 1529289359 @default.
• W1529289359 citedByCount "98" @default.
• W1529289359 countsByYear W15292893592012 @default.
• W1529289359 countsByYear W15292893592013 @default.
• W1529289359 countsByYear W15292893592014 @default.
• W1529289359 countsByYear W15292893592015 @default.
• W1529289359 countsByYear W15292893592016 @default.
• W1529289359 countsByYear W15292893592017 @default.
• W1529289359 countsByYear W15292893592018 @default.
• W1529289359 countsByYear W15292893592019 @default.
• W1529289359 countsByYear W15292893592020 @default.
• W1529289359 countsByYear W15292893592021 @default.
• W1529289359 countsByYear W15292893592022 @default.
• W1529289359 countsByYear W15292893592023 @default.
• W1529289359 crossrefType "journal-article" @default.
• W1529289359 hasAuthorship W1529289359A5015138528 @default.
• W1529289359 hasAuthorship W1529289359A5017600752 @default.
• W1529289359 hasAuthorship W1529289359A5030369550 @default.
• W1529289359 hasAuthorship W1529289359A5048328154 @default.
• W1529289359 hasAuthorship W1529289359A5050361725 @default.
• W1529289359 hasAuthorship W1529289359A5059223836 @default.
• W1529289359 hasAuthorship W1529289359A5065648265 @default.
• W1529289359 hasAuthorship W1529289359A5078425072 @default.
• W1529289359 hasAuthorship W1529289359A5088621336 @default.
• W1529289359 hasBestOaLocation W15292893591 @default.
• W1529289359 hasConcept C105702510 @default.
• W1529289359 hasConcept C120770815 @default.
• W1529289359 hasConcept C126322002 @default.
• W1529289359 hasConcept C139940330 @default.
• W1529289359 hasConcept C146957229 @default.
• W1529289359 hasConcept C158846371 @default.

• next