FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1529482445> ?p ?o ?g. }

• W1529482445 endingPage "1244" @default.
• W1529482445 startingPage "1236" @default.
• W1529482445 abstract "Abstract Objectives The goal of this work was to evaluate the ability of ethanol mixed with hydrofluoroalkanes (HFAs) to improve solvation of moieties of relevance to pressurized metered-dose inhalers (pMDIs). Methods Chemical force microscopy was used to measure the adhesion force (Fad) between alkyl-based, ether-based and ester-based moieties (C8/C8, COC/COC and COOC/COOC interactions) in 2H,3H-perfluoropentane (HPFP)/ethanol mixtures. HPFP is a liquid that mimics propellant HFAs. The Fad results are thus a measure of solvation in HFAs. Johnson–Kendall–Roberts (JKR) theory was used to model the results. Key findings The Fad normalized by the tip radius of curvature (Fad/R) decreased upon the addition of ethanol, suggesting its ability to enhance the solvent environment. At 15% (v/v) ethanol, the Fad/R was reduced 34% for the alkyl, 63% for the ether, and down 67% for the ester tails. Thus, the solvation could be ranked as: ester &gt; ether &gt; alkyl. JKR theory was a reasonable model for the Fad/R. Conclusions Ethanol, within the concentration range of interest in commercial pMDIs, provided limited enhancement in solvation of alkyl moieties. On the other hand, the cosolvent significantly enhanced solvation of ether-based and ester-based moieties, thus suggesting its potential for formulations containing amphiphiles with such groups." @default.
• W1529482445 created "2016-06-24" @default.
• W1529482445 creator A5021848694 @default.
• W1529482445 creator A5047963541 @default.
• W1529482445 creator A5059163160 @default.
• W1529482445 creator A5075941140 @default.
• W1529482445 creator A5090344982 @default.
• W1529482445 date "2011-11-18" @default.
• W1529482445 modified "2023-09-26" @default.
• W1529482445 title "Solvation in hydrofluoroalkanes: how can ethanol help?" @default.
• W1529482445 cites W1971115807 @default.
• W1529482445 cites W1971274480 @default.
• W1529482445 cites W1972983870 @default.
• W1529482445 cites W1983273726 @default.
• W1529482445 cites W1988010146 @default.
• W1529482445 cites W1988636074 @default.
• W1529482445 cites W1995818918 @default.
• W1529482445 cites W1998046526 @default.
• W1529482445 cites W1998673674 @default.
• W1529482445 cites W2000905651 @default.
• W1529482445 cites W2002279154 @default.
• W1529482445 cites W2016863438 @default.
• W1529482445 cites W2019005351 @default.
• W1529482445 cites W2022069744 @default.
• W1529482445 cites W2024980028 @default.
• W1529482445 cites W2027842762 @default.
• W1529482445 cites W2028069233 @default.
• W1529482445 cites W2029537352 @default.
• W1529482445 cites W2039282390 @default.
• W1529482445 cites W2045467856 @default.
• W1529482445 cites W2049203706 @default.
• W1529482445 cites W2050833508 @default.
• W1529482445 cites W2060632482 @default.
• W1529482445 cites W2063900133 @default.
• W1529482445 cites W2066347213 @default.
• W1529482445 cites W2067869352 @default.
• W1529482445 cites W2070768894 @default.
• W1529482445 cites W2072589287 @default.
• W1529482445 cites W2087421574 @default.
• W1529482445 cites W2088383468 @default.
• W1529482445 cites W2088811629 @default.
• W1529482445 cites W2105665577 @default.
• W1529482445 cites W2112896993 @default.
• W1529482445 cites W2131905205 @default.
• W1529482445 cites W2134819724 @default.
• W1529482445 cites W2145606419 @default.
• W1529482445 cites W2150903279 @default.
• W1529482445 cites W2154718337 @default.
• W1529482445 cites W2155854731 @default.
• W1529482445 cites W2173489425 @default.
• W1529482445 cites W2492289546 @default.
• W1529482445 cites W3022711947 @default.
• W1529482445 cites W3121345441 @default.
• W1529482445 cites W4229884962 @default.
• W1529482445 cites W4321429513 @default.
• W1529482445 cites W52954511 @default.
• W1529482445 cites W74645961 @default.
• W1529482445 doi "https://doi.org/10.1111/j.2042-7158.2011.01398.x" @default.
• W1529482445 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22881436" @default.
• W1529482445 hasPublicationYear "2011" @default.
• W1529482445 type Work @default.
• W1529482445 sameAs 1529482445 @default.
• W1529482445 citedByCount "5" @default.
• W1529482445 countsByYear W15294824452014 @default.
• W1529482445 countsByYear W15294824452016 @default.
• W1529482445 countsByYear W15294824452017 @default.
• W1529482445 countsByYear W15294824452018 @default.
• W1529482445 crossrefType "journal-article" @default.
• W1529482445 hasAuthorship W1529482445A5021848694 @default.
• W1529482445 hasAuthorship W1529482445A5047963541 @default.
• W1529482445 hasAuthorship W1529482445A5059163160 @default.
• W1529482445 hasAuthorship W1529482445A5075941140 @default.
• W1529482445 hasAuthorship W1529482445A5090344982 @default.
• W1529482445 hasConcept C11268172 @default.
• W1529482445 hasConcept C148093993 @default.
• W1529482445 hasConcept C178790620 @default.
• W1529482445 hasConcept C184651966 @default.
• W1529482445 hasConcept C185592680 @default.
• W1529482445 hasConcept C207374878 @default.
• W1529482445 hasConcept C2780161600 @default.
• W1529482445 hasConcept C2780263894 @default.
• W1529482445 hasConcept C2780407432 @default.
• W1529482445 hasConcept C2780471494 @default.
• W1529482445 hasConceptScore W1529482445C11268172 @default.
• W1529482445 hasConceptScore W1529482445C148093993 @default.
• W1529482445 hasConceptScore W1529482445C178790620 @default.
• W1529482445 hasConceptScore W1529482445C184651966 @default.
• W1529482445 hasConceptScore W1529482445C185592680 @default.
• W1529482445 hasConceptScore W1529482445C207374878 @default.
• W1529482445 hasConceptScore W1529482445C2780161600 @default.
• W1529482445 hasConceptScore W1529482445C2780263894 @default.
• W1529482445 hasConceptScore W1529482445C2780407432 @default.
• W1529482445 hasConceptScore W1529482445C2780471494 @default.
• W1529482445 hasIssue "9" @default.
• W1529482445 hasLocation W15294824451 @default.
• W1529482445 hasLocation W15294824452 @default.
• W1529482445 hasOpenAccess W1529482445 @default.
• W1529482445 hasPrimaryLocation W15294824451 @default.

• next