Matches in SemOpenAlex for { <https://semopenalex.org/work/W1529838049> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1529838049 endingPage "319" @default.
- W1529838049 startingPage "313" @default.
- W1529838049 abstract "Neuroendocrine deficiencies have been implicated in fibromyalgia (FM). In the present study, adrenal androgen metabolites and their relationship with health status in FM were investigated. For comparison, serum levels of other implicated neuroendocrine mediators were correlated with health status. Fifty-seven consecutive women with FM completed the Fibromyalgia Impact Questionnaire (FIQ). Fasting blood samples were taken for measurement of dehydroepiandrosterone sulphate (DHEAS), free testosterone (T), cortisol, serotonin and insulin-like growth factor-1. Normal value for DHEAS and T were obtained from 114 controls. DHEAS levels were decreased significantly in pre- and postmenopausal patients (P<0.0001 and P<0.0005, respectively). T levels were decreased significantly in premenopausal and insignificantly in postmenopausal patients (P<0.0001 and P=0.06, respectively). The following correlations between neurohormonal levels and FIQ scores were found: DHEAS (after adjustment for age) vs. pain (P<0.001) and T (after adjustment for age) versus physical functioning (P=0.002). None of the other neurohormonal levels correlated significantly with any of the FIQ scores. IGF-1 levels were lower in the obese patients as compared to those who were non-obese (P=0.03). The BMI correlated positively with pain (P<0. 001) and inversely with DHEAS levels (P=0.006). After further adjustment for BMI, the correlation between age adjusted DHEAS and pain was no longer significant. Hyposecretion of adrenal androgens was documented in FM. This was more pronounced in obese patients. Low serum androgen levels correlated with poor health status in FM. Longitudinal studies are needed to elucidate whether these are cause and/or effect relationships." @default.
- W1529838049 created "2016-06-24" @default.
- W1529838049 creator A5042634931 @default.
- W1529838049 creator A5047358297 @default.
- W1529838049 creator A5056131415 @default.
- W1529838049 creator A5073280020 @default.
- W1529838049 creator A5079736464 @default.
- W1529838049 creator A5081159079 @default.
- W1529838049 date "1999-11-01" @default.
- W1529838049 modified "2023-10-18" @default.
- W1529838049 title "Hyposecretion of adrenal androgens and the relation of serum adrenal steroids, serotonin and insulin-like growth factor-1 to clinical features in women with fibromyalgia" @default.
- W1529838049 cites W150360325 @default.
- W1529838049 cites W1991556052 @default.
- W1529838049 cites W2004648105 @default.
- W1529838049 cites W2041481324 @default.
- W1529838049 cites W2054990978 @default.
- W1529838049 cites W2065686737 @default.
- W1529838049 cites W2082566411 @default.
- W1529838049 cites W2095317275 @default.
- W1529838049 cites W2101709958 @default.
- W1529838049 cites W2125439077 @default.
- W1529838049 cites W2150622706 @default.
- W1529838049 cites W2151099642 @default.
- W1529838049 cites W2253364553 @default.
- W1529838049 cites W4245094306 @default.
- W1529838049 cites W4294184534 @default.
- W1529838049 doi "https://doi.org/10.1016/s0304-3959(99)00113-x" @default.
- W1529838049 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10534604" @default.
- W1529838049 hasPublicationYear "1999" @default.
- W1529838049 type Work @default.
- W1529838049 sameAs 1529838049 @default.
- W1529838049 citedByCount "67" @default.
- W1529838049 countsByYear W15298380492012 @default.
- W1529838049 countsByYear W15298380492013 @default.
- W1529838049 countsByYear W15298380492014 @default.
- W1529838049 countsByYear W15298380492015 @default.
- W1529838049 countsByYear W15298380492016 @default.
- W1529838049 countsByYear W15298380492017 @default.
- W1529838049 countsByYear W15298380492020 @default.
- W1529838049 countsByYear W15298380492021 @default.
- W1529838049 countsByYear W15298380492022 @default.
- W1529838049 countsByYear W15298380492023 @default.
- W1529838049 crossrefType "journal-article" @default.
- W1529838049 hasAuthorship W1529838049A5042634931 @default.
- W1529838049 hasAuthorship W1529838049A5047358297 @default.
- W1529838049 hasAuthorship W1529838049A5056131415 @default.
- W1529838049 hasAuthorship W1529838049A5073280020 @default.
- W1529838049 hasAuthorship W1529838049A5079736464 @default.
- W1529838049 hasAuthorship W1529838049A5081159079 @default.
- W1529838049 hasConcept C126322002 @default.
- W1529838049 hasConcept C134018914 @default.
- W1529838049 hasConcept C2776405666 @default.
- W1529838049 hasConcept C2776992908 @default.
- W1529838049 hasConcept C2777831278 @default.
- W1529838049 hasConcept C2777911890 @default.
- W1529838049 hasConcept C2779279991 @default.
- W1529838049 hasConcept C2780657110 @default.
- W1529838049 hasConcept C2780841215 @default.
- W1529838049 hasConcept C30092816 @default.
- W1529838049 hasConcept C71315377 @default.
- W1529838049 hasConcept C71924100 @default.
- W1529838049 hasConceptScore W1529838049C126322002 @default.
- W1529838049 hasConceptScore W1529838049C134018914 @default.
- W1529838049 hasConceptScore W1529838049C2776405666 @default.
- W1529838049 hasConceptScore W1529838049C2776992908 @default.
- W1529838049 hasConceptScore W1529838049C2777831278 @default.
- W1529838049 hasConceptScore W1529838049C2777911890 @default.
- W1529838049 hasConceptScore W1529838049C2779279991 @default.
- W1529838049 hasConceptScore W1529838049C2780657110 @default.
- W1529838049 hasConceptScore W1529838049C2780841215 @default.
- W1529838049 hasConceptScore W1529838049C30092816 @default.
- W1529838049 hasConceptScore W1529838049C71315377 @default.
- W1529838049 hasConceptScore W1529838049C71924100 @default.
- W1529838049 hasIssue "2" @default.
- W1529838049 hasLocation W15298380491 @default.
- W1529838049 hasLocation W15298380492 @default.
- W1529838049 hasOpenAccess W1529838049 @default.
- W1529838049 hasPrimaryLocation W15298380491 @default.
- W1529838049 hasRelatedWork W1980417275 @default.
- W1529838049 hasRelatedWork W2002917234 @default.
- W1529838049 hasRelatedWork W2023189202 @default.
- W1529838049 hasRelatedWork W2077442251 @default.
- W1529838049 hasRelatedWork W2083344966 @default.
- W1529838049 hasRelatedWork W2117196859 @default.
- W1529838049 hasRelatedWork W2150421446 @default.
- W1529838049 hasRelatedWork W2415262826 @default.
- W1529838049 hasRelatedWork W2415632568 @default.
- W1529838049 hasRelatedWork W2419379761 @default.
- W1529838049 hasVolume "83" @default.
- W1529838049 isParatext "false" @default.
- W1529838049 isRetracted "false" @default.
- W1529838049 magId "1529838049" @default.
- W1529838049 workType "article" @default.