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• W1530434417 abstract "The substitution of tris/HCl buffer by CO(2)/HCO(3)(-) buffer in inorganic plasma was studied. An appropriate gas mixture of CO(2)/N(2) was continuously bubbled in Kokubo's SBF solution prepared without addition of Tris/HCl. This method enables buffering the solution within the 7.3-7.4 pH interval and, at the same time, reaching a HCO(3)(-) concentration between 24 and 27 mmol dm(-3), which are the normal concentrations reported for blood plasma. Mineralisation studies on calcium phosphate ceramics using this solution showed that, in the presence of such hydrogencarbonate concentrations, the formation of a mineralisation layer on the ceramic occurs via a carbonated octacalcium phosphate, that evolves to carbonated hydroxyapatite. The results suggest that mineralisation studies in this new carbonate-containing simulated inorganic plasma mimic biomineralisation more closely than traditional SBF." @default.
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• W1530434417 date "2003-04-01" @default.
• W1530434417 modified "2023-10-16" @default.
• W1530434417 title "Inorganic plasma with physiological CO2/HCO3− buffer" @default.
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• W1530434417 doi "https://doi.org/10.1016/s0142-9612(02)00539-2" @default.
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