Matches in SemOpenAlex for { <https://semopenalex.org/work/W1530889613> ?p ?o ?g. }
- W1530889613 endingPage "369" @default.
- W1530889613 startingPage "359" @default.
- W1530889613 abstract "Immunohistological analysis of the expression of lactase protein in adults with hypolactasia has been carried out using monoclonal antibodies. Eight different antibodies that recognize at least three distinct epitopes on the lactase protein each gave the same result. Strong brush border staining was observed in all the lactase-persistent adults. No staining at all was detected in 9 of the hypolactasic subjects. In the remaining 12 individuals a mosaic pattern of expression was observed: small patches of enterocytes stained strongly, whereas the surrounding areas showed no staining at all. Sucrase-isomaltase, in contrast, showed no such mosaicism in these or in any of the other individuals. The mosaicism observed in the 12 hypolactasic individuals suggests that the differentiation of the columnar cells along the villus is not homogeneous. Furthermore, the existence of two patterns of expression of the lactase protein in the lactase-deficient individuals (i.e., absence of protein and mosaicism), if characteristic of the entire length of the intestine of the individuals tested, would suggest the existence of two phenotypes of adult-type hypolactasia in the population studied." @default.
- W1530889613 created "2016-06-24" @default.
- W1530889613 creator A5001271961 @default.
- W1530889613 creator A5006141192 @default.
- W1530889613 creator A5013343324 @default.
- W1530889613 creator A5021144829 @default.
- W1530889613 creator A5024359244 @default.
- W1530889613 creator A5028007261 @default.
- W1530889613 creator A5031675171 @default.
- W1530889613 creator A5054084267 @default.
- W1530889613 creator A5070062674 @default.
- W1530889613 creator A5070114434 @default.
- W1530889613 creator A5079058220 @default.
- W1530889613 date "1991-02-01" @default.
- W1530889613 modified "2023-09-29" @default.
- W1530889613 title "Mosaic pattern of lactase expression by villous enterocytes in human adult-type hypolactasia" @default.
- W1530889613 cites W1599209789 @default.
- W1530889613 cites W1921570207 @default.
- W1530889613 cites W1969589951 @default.
- W1530889613 cites W1981930796 @default.
- W1530889613 cites W1984045747 @default.
- W1530889613 cites W1986412439 @default.
- W1530889613 cites W1994830684 @default.
- W1530889613 cites W1996533617 @default.
- W1530889613 cites W200081977 @default.
- W1530889613 cites W2002079142 @default.
- W1530889613 cites W2010057578 @default.
- W1530889613 cites W2018313564 @default.
- W1530889613 cites W2018995260 @default.
- W1530889613 cites W2026925931 @default.
- W1530889613 cites W2029146706 @default.
- W1530889613 cites W2032247941 @default.
- W1530889613 cites W2047430682 @default.
- W1530889613 cites W2048988574 @default.
- W1530889613 cites W2053700159 @default.
- W1530889613 cites W2063317846 @default.
- W1530889613 cites W2071126460 @default.
- W1530889613 cites W2074811051 @default.
- W1530889613 cites W2092393393 @default.
- W1530889613 cites W2096428903 @default.
- W1530889613 cites W2097598566 @default.
- W1530889613 cites W2117147135 @default.
- W1530889613 cites W2126723452 @default.
- W1530889613 cites W2157018895 @default.
- W1530889613 cites W2414388501 @default.
- W1530889613 cites W4298176356 @default.
- W1530889613 doi "https://doi.org/10.1016/0016-5085(91)90203-w" @default.
- W1530889613 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1702075" @default.
- W1530889613 hasPublicationYear "1991" @default.
- W1530889613 type Work @default.
- W1530889613 sameAs 1530889613 @default.
- W1530889613 citedByCount "93" @default.
- W1530889613 countsByYear W15308896132012 @default.
- W1530889613 countsByYear W15308896132013 @default.
- W1530889613 countsByYear W15308896132014 @default.
- W1530889613 countsByYear W15308896132015 @default.
- W1530889613 countsByYear W15308896132016 @default.
- W1530889613 countsByYear W15308896132017 @default.
- W1530889613 countsByYear W15308896132018 @default.
- W1530889613 countsByYear W15308896132019 @default.
- W1530889613 countsByYear W15308896132021 @default.
- W1530889613 countsByYear W15308896132022 @default.
- W1530889613 crossrefType "journal-article" @default.
- W1530889613 hasAuthorship W1530889613A5001271961 @default.
- W1530889613 hasAuthorship W1530889613A5006141192 @default.
- W1530889613 hasAuthorship W1530889613A5013343324 @default.
- W1530889613 hasAuthorship W1530889613A5021144829 @default.
- W1530889613 hasAuthorship W1530889613A5024359244 @default.
- W1530889613 hasAuthorship W1530889613A5028007261 @default.
- W1530889613 hasAuthorship W1530889613A5031675171 @default.
- W1530889613 hasAuthorship W1530889613A5054084267 @default.
- W1530889613 hasAuthorship W1530889613A5070062674 @default.
- W1530889613 hasAuthorship W1530889613A5070114434 @default.
- W1530889613 hasAuthorship W1530889613A5079058220 @default.
- W1530889613 hasBestOaLocation W15308896131 @default.
- W1530889613 hasConcept C104317684 @default.
- W1530889613 hasConcept C127716648 @default.
- W1530889613 hasConcept C130316041 @default.
- W1530889613 hasConcept C153911025 @default.
- W1530889613 hasConcept C159654299 @default.
- W1530889613 hasConcept C181199279 @default.
- W1530889613 hasConcept C195616568 @default.
- W1530889613 hasConcept C203014093 @default.
- W1530889613 hasConcept C204232928 @default.
- W1530889613 hasConcept C2776039999 @default.
- W1530889613 hasConcept C2778724459 @default.
- W1530889613 hasConcept C2778974006 @default.
- W1530889613 hasConcept C2908647359 @default.
- W1530889613 hasConcept C41625074 @default.
- W1530889613 hasConcept C5426402 @default.
- W1530889613 hasConcept C54355233 @default.
- W1530889613 hasConcept C55493867 @default.
- W1530889613 hasConcept C71924100 @default.
- W1530889613 hasConcept C74864618 @default.
- W1530889613 hasConcept C86803240 @default.
- W1530889613 hasConcept C99454951 @default.
- W1530889613 hasConceptScore W1530889613C104317684 @default.
- W1530889613 hasConceptScore W1530889613C127716648 @default.