Matches in SemOpenAlex for { <https://semopenalex.org/work/W1530933041> ?p ?o ?g. }
- W1530933041 endingPage "2751" @default.
- W1530933041 startingPage "2745" @default.
- W1530933041 abstract "Abstract We have investigated the involvement of chemokine receptor CCR1-positive cells in bleomycin-induced lung injury, a model of pulmonary fibrosis. After bleomycin challenge in C57BL/6J mice, the expression of CCR1 mRNA increased and peaked at day 7, which paralleled to the expression of its ligands, macrophage-inflammatory protein-1α and RANTES. Immunohistochemical study showed that CCR1-positive cells accumulated in the interstitial inflammatory site. Furthermore, the treatment of anti-CCR1 Ab significantly reduced the accumulation of inflammatory cells and collagen deposition, resulting in dramatic improvement of survival. These results suggest that CCR1-positive cells play significant roles in the pathogenesis of pulmonary fibrosis subsequent to bleomycin-induced lung injury, and that CCR1 could be a novel molecular target for intervention therapy against pulmonary fibrosis." @default.
- W1530933041 created "2016-06-24" @default.
- W1530933041 creator A5005730268 @default.
- W1530933041 creator A5024660569 @default.
- W1530933041 creator A5036834366 @default.
- W1530933041 creator A5069154786 @default.
- W1530933041 creator A5069805233 @default.
- W1530933041 creator A5071566737 @default.
- W1530933041 date "2000-03-01" @default.
- W1530933041 modified "2023-10-16" @default.
- W1530933041 title "Pivotal Role of CCR1-Positive Leukocytes in Bleomycin- Induced Lung Fibrosis in Mice" @default.
- W1530933041 cites W1495215438 @default.
- W1530933041 cites W1559594041 @default.
- W1530933041 cites W1584506674 @default.
- W1530933041 cites W1589432660 @default.
- W1530933041 cites W1602835962 @default.
- W1530933041 cites W1604292228 @default.
- W1530933041 cites W1760557207 @default.
- W1530933041 cites W1909933445 @default.
- W1530933041 cites W1964616348 @default.
- W1530933041 cites W1992443433 @default.
- W1530933041 cites W1997666213 @default.
- W1530933041 cites W1998975199 @default.
- W1530933041 cites W2020554497 @default.
- W1530933041 cites W2035616952 @default.
- W1530933041 cites W2048046765 @default.
- W1530933041 cites W2107491460 @default.
- W1530933041 cites W2108830193 @default.
- W1530933041 cites W2111718223 @default.
- W1530933041 cites W2124328573 @default.
- W1530933041 cites W2126586446 @default.
- W1530933041 cites W2130616801 @default.
- W1530933041 cites W2132305071 @default.
- W1530933041 cites W2133029085 @default.
- W1530933041 cites W2144403535 @default.
- W1530933041 cites W2151172616 @default.
- W1530933041 cites W2159827153 @default.
- W1530933041 cites W2160001887 @default.
- W1530933041 cites W2184678082 @default.
- W1530933041 cites W2338349263 @default.
- W1530933041 cites W2345668341 @default.
- W1530933041 cites W4313379046 @default.
- W1530933041 doi "https://doi.org/10.4049/jimmunol.164.5.2745" @default.
- W1530933041 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10679116" @default.
- W1530933041 hasPublicationYear "2000" @default.
- W1530933041 type Work @default.
- W1530933041 sameAs 1530933041 @default.
- W1530933041 citedByCount "101" @default.
- W1530933041 countsByYear W15309330412012 @default.
- W1530933041 countsByYear W15309330412013 @default.
- W1530933041 countsByYear W15309330412014 @default.
- W1530933041 countsByYear W15309330412015 @default.
- W1530933041 countsByYear W15309330412017 @default.
- W1530933041 countsByYear W15309330412018 @default.
- W1530933041 countsByYear W15309330412019 @default.
- W1530933041 countsByYear W15309330412020 @default.
- W1530933041 countsByYear W15309330412021 @default.
- W1530933041 countsByYear W15309330412022 @default.
- W1530933041 countsByYear W15309330412023 @default.
- W1530933041 crossrefType "journal-article" @default.
- W1530933041 hasAuthorship W1530933041A5005730268 @default.
- W1530933041 hasAuthorship W1530933041A5024660569 @default.
- W1530933041 hasAuthorship W1530933041A5036834366 @default.
- W1530933041 hasAuthorship W1530933041A5069154786 @default.
- W1530933041 hasAuthorship W1530933041A5069805233 @default.
- W1530933041 hasAuthorship W1530933041A5071566737 @default.
- W1530933041 hasBestOaLocation W15309330411 @default.
- W1530933041 hasConcept C126322002 @default.
- W1530933041 hasConcept C12823836 @default.
- W1530933041 hasConcept C129013479 @default.
- W1530933041 hasConcept C13373296 @default.
- W1530933041 hasConcept C142724271 @default.
- W1530933041 hasConcept C203014093 @default.
- W1530933041 hasConcept C206615009 @default.
- W1530933041 hasConcept C2776232574 @default.
- W1530933041 hasConcept C2776694085 @default.
- W1530933041 hasConcept C2776914184 @default.
- W1530933041 hasConcept C2777714996 @default.
- W1530933041 hasConcept C2780559512 @default.
- W1530933041 hasConcept C2780942790 @default.
- W1530933041 hasConcept C2781244666 @default.
- W1530933041 hasConcept C502942594 @default.
- W1530933041 hasConcept C71924100 @default.
- W1530933041 hasConceptScore W1530933041C126322002 @default.
- W1530933041 hasConceptScore W1530933041C12823836 @default.
- W1530933041 hasConceptScore W1530933041C129013479 @default.
- W1530933041 hasConceptScore W1530933041C13373296 @default.
- W1530933041 hasConceptScore W1530933041C142724271 @default.
- W1530933041 hasConceptScore W1530933041C203014093 @default.
- W1530933041 hasConceptScore W1530933041C206615009 @default.
- W1530933041 hasConceptScore W1530933041C2776232574 @default.
- W1530933041 hasConceptScore W1530933041C2776694085 @default.
- W1530933041 hasConceptScore W1530933041C2776914184 @default.
- W1530933041 hasConceptScore W1530933041C2777714996 @default.
- W1530933041 hasConceptScore W1530933041C2780559512 @default.
- W1530933041 hasConceptScore W1530933041C2780942790 @default.
- W1530933041 hasConceptScore W1530933041C2781244666 @default.
- W1530933041 hasConceptScore W1530933041C502942594 @default.