Matches in SemOpenAlex for { <https://semopenalex.org/work/W1532082751> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1532082751 endingPage "11660" @default.
- W1532082751 startingPage "11654" @default.
- W1532082751 abstract "A fluorescent compound has been detected in proteins browned during Maillard reactions with glucose in vitro and shown to be identical to pentosidine, a pentose-derived fluorescent cross-link formed between arginine and lysine residues in collagen (Sell, D. R., and Monnier, V. M. (1989) J. Biol. Chem. 264, 21597-21602). Pentosidine was the major fluorophore formed during nonenzymatic browning of ribonuclease and lysozyme by glucose, but accounted for less than 1% of non-disulfide cross-links in protein dimers formed during the reaction. Pentosidine was formed in greatest yields in reactions of pentoses with lysine and arginine in model systems but was also formed from glucose, fructose, ascorbate, Amadori compounds, 3-deoxyglucosone, and other sugars. Pentosidine was not formed from peroxidized polyunsaturated fatty acids or malondialdehyde. Its formation from carbohydrates was inhibited under nitrogen or anaerobic conditions and by aminoguanidine, an inhibitor of advanced glycation and browning reactions. Pentosidine was detected in human lens proteins, where its concentration increased gradually with age, but it did not exceed trace concentrations (less than or equal to 5 mumol/mol lysine), even in the 80-year-old lens. Although its precise carbohydrate source in vivo is uncertain and it is present in only trace concentrations in tissue proteins, pentosidine appears to be a useful biomarker for assessing cumulative damage to proteins by nonenzymatic browning reactions with carbohydrates." @default.
- W1532082751 created "2016-06-24" @default.
- W1532082751 creator A5001291710 @default.
- W1532082751 creator A5027607783 @default.
- W1532082751 creator A5075469719 @default.
- W1532082751 creator A5087140822 @default.
- W1532082751 date "1991-06-01" @default.
- W1532082751 modified "2023-10-14" @default.
- W1532082751 title "Formation of pentosidine during nonenzymatic browning of proteins by glucose. Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo" @default.
- W1532082751 cites W1479724237 @default.
- W1532082751 cites W1509683120 @default.
- W1532082751 cites W1532307989 @default.
- W1532082751 cites W1556333628 @default.
- W1532082751 cites W1557253076 @default.
- W1532082751 cites W1609735481 @default.
- W1532082751 cites W1976068063 @default.
- W1532082751 cites W1996526251 @default.
- W1532082751 cites W2001214137 @default.
- W1532082751 cites W2003985793 @default.
- W1532082751 cites W2016184962 @default.
- W1532082751 cites W2032055976 @default.
- W1532082751 cites W2045887607 @default.
- W1532082751 cites W2052681712 @default.
- W1532082751 cites W2058345849 @default.
- W1532082751 cites W2069942321 @default.
- W1532082751 cites W2075049539 @default.
- W1532082751 cites W2077034296 @default.
- W1532082751 cites W2082534981 @default.
- W1532082751 cites W2086036799 @default.
- W1532082751 cites W2117086217 @default.
- W1532082751 cites W2135433859 @default.
- W1532082751 cites W2327070276 @default.
- W1532082751 cites W2337292567 @default.
- W1532082751 doi "https://doi.org/10.1016/s0021-9258(18)99007-1" @default.
- W1532082751 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1904867" @default.
- W1532082751 hasPublicationYear "1991" @default.
- W1532082751 type Work @default.
- W1532082751 sameAs 1532082751 @default.
- W1532082751 citedByCount "476" @default.
- W1532082751 countsByYear W15320827512012 @default.
- W1532082751 countsByYear W15320827512013 @default.
- W1532082751 countsByYear W15320827512014 @default.
- W1532082751 countsByYear W15320827512015 @default.
- W1532082751 countsByYear W15320827512016 @default.
- W1532082751 countsByYear W15320827512017 @default.
- W1532082751 countsByYear W15320827512018 @default.
- W1532082751 countsByYear W15320827512019 @default.
- W1532082751 countsByYear W15320827512020 @default.
- W1532082751 countsByYear W15320827512021 @default.
- W1532082751 countsByYear W15320827512022 @default.
- W1532082751 countsByYear W15320827512023 @default.
- W1532082751 crossrefType "journal-article" @default.
- W1532082751 hasAuthorship W1532082751A5001291710 @default.
- W1532082751 hasAuthorship W1532082751A5027607783 @default.
- W1532082751 hasAuthorship W1532082751A5075469719 @default.
- W1532082751 hasAuthorship W1532082751A5087140822 @default.
- W1532082751 hasBestOaLocation W15320827511 @default.
- W1532082751 hasConcept C147990577 @default.
- W1532082751 hasConcept C150903083 @default.
- W1532082751 hasConcept C170493617 @default.
- W1532082751 hasConcept C185592680 @default.
- W1532082751 hasConcept C207001950 @default.
- W1532082751 hasConcept C2778977261 @default.
- W1532082751 hasConcept C2780758796 @default.
- W1532082751 hasConcept C35378473 @default.
- W1532082751 hasConcept C53007507 @default.
- W1532082751 hasConcept C55493867 @default.
- W1532082751 hasConcept C86803240 @default.
- W1532082751 hasConceptScore W1532082751C147990577 @default.
- W1532082751 hasConceptScore W1532082751C150903083 @default.
- W1532082751 hasConceptScore W1532082751C170493617 @default.
- W1532082751 hasConceptScore W1532082751C185592680 @default.
- W1532082751 hasConceptScore W1532082751C207001950 @default.
- W1532082751 hasConceptScore W1532082751C2778977261 @default.
- W1532082751 hasConceptScore W1532082751C2780758796 @default.
- W1532082751 hasConceptScore W1532082751C35378473 @default.
- W1532082751 hasConceptScore W1532082751C53007507 @default.
- W1532082751 hasConceptScore W1532082751C55493867 @default.
- W1532082751 hasConceptScore W1532082751C86803240 @default.
- W1532082751 hasIssue "18" @default.
- W1532082751 hasLocation W15320827511 @default.
- W1532082751 hasOpenAccess W1532082751 @default.
- W1532082751 hasPrimaryLocation W15320827511 @default.
- W1532082751 hasRelatedWork W2039842631 @default.
- W1532082751 hasRelatedWork W2050486668 @default.
- W1532082751 hasRelatedWork W2386992152 @default.
- W1532082751 hasRelatedWork W2410509351 @default.
- W1532082751 hasRelatedWork W24379311 @default.
- W1532082751 hasRelatedWork W2493277736 @default.
- W1532082751 hasRelatedWork W2794650610 @default.
- W1532082751 hasRelatedWork W2908598314 @default.
- W1532082751 hasRelatedWork W5827430 @default.
- W1532082751 hasRelatedWork W3021933146 @default.
- W1532082751 hasVolume "266" @default.
- W1532082751 isParatext "false" @default.
- W1532082751 isRetracted "false" @default.
- W1532082751 magId "1532082751" @default.
- W1532082751 workType "article" @default.