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- W1532409605 abstract "Specific aimsThe aim is to improve the treatment of the bone losses at the metacarpal bones level (bothdiaphysis and epiphysis) combining microsurgery, tissue engineering and biomaterials, so tominimize the donor side morbidity and optimize healing and outcomes.MethodsPre-operative controlateral X-ray or 3-D CT to allow custom-made HA scaffolds. Cement astemporary spacer in acute lesion and monitoring of infective risks. Treatment of the bone lossrecurring to pre-fabricated or custom-made HA scaffolds, adding platelet gel or growth factorOP1. Stable synthesis. Control group with auto/omografts. Outcome indices: % of bone-union;finger TAM, Kapandji, DASH score; NMR and Scintigraphy at 180 days for revascularisationand bio-substitution of the scaffold.Preliminary resultsThe authors just treated 6 patients, 4 males and 2 females, with an average age of 38.5 yrs,affected by segmental bone losses at the hand and wrist, recurring to pre-fabricated notvascularised scaffolds. In all cases the synthesis was performed with angular stability plates anda stable synthesis achieved. All patients have been controlled at a mean follow-up of 10.5months (from 2 to 16 ). In all case but one the bone-scaffold osteo-integration was achieved at anaverage of 38 days at the hand, and 46 days at the wrist. The outcome studies, according to theDASH score, finger TAM, and Kapandji, were good and excellent in 5 cases, poor in one." @default.
- W1532409605 created "2016-06-24" @default.
- W1532409605 creator A5038079010 @default.
- W1532409605 date "2008-05-15" @default.
- W1532409605 modified "2023-09-23" @default.
- W1532409605 title "COSTRUZIONE DI UNO SCAFFOLD VASCOLARIZZATO PER LA CHIRURGIA ORTOPEDICA" @default.
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- W1532409605 doi "https://doi.org/10.6092/unibo/amsdottorato/704" @default.
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