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- W1532689538 abstract "Enhanced oxidative stress and changes in antioxidant capacity are considered to play an important role in the pathogenesis of chronic diabetes mellitus. Wistar male rat (n=40) were allocated into three groups, control group (n=10) and quercetin (QR) group th at received 15mg/kg (IP) QR, (n=10), and Diabetic group th at received 55mg/kg (IP) streptozotocin (STZ) (n=20) which was subdivided to two groups of 10; STZ group and treatment group. Treatment group received 55mg/kg (IP) STZ plus 15mg/kg QR, daily for 4 weeks, respectively; however, the control group just received an equal volume of distilled water daily(IP) . Diabetes were induced by a single (IP) injection of streptozotocin (55mg/kg). Animals were kept in standard condition. In 28 day after inducing diabetic 5 mL blood were collected for Total Antioxidant Capacity (TAC), Malondi Dehyde (MDA) and Oxidized Low density Lipoprotein (Ox-LDL) levels and kidney tissues of Rat in whole groups were removed then prepared for Apoptosis analysis by Tunel metho. Apoptotic cells significantly decreased in group th at has received 15mg/kg (IP) quercetin (P" @default.
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- W1532689538 title "QUERCETIN CAUSES TO DECREASE PROXIMAL TUBULES APOPTOTIC CELLS IN STREPTOZOTOCIN-INDUCED DIABETIC RAT" @default.
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