FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1533071520> ?p ?o ?g. }

• W1533071520 abstract "Personalized medicine is the most promising approaches in the treatment of various diseases, especially cancer. The use of appropriate biomarkers for personalized treatment has advantage over conventional therapeutics approach, as it confer maximum effectiveness with minimum side effect. Personalized treatment can be achieved by implementation of omic studies in clinical practices. Application of genomic, transcriptomic, proteomic and metabolomic studies deliver a vast amount of data that lead to the discovery of novel biomarkers for diagnostic, prognostic and therapeutic purposes. Therefore, further exploration in omic study could lead to the implementation of personalized medicine as a standard therapeutic scheme in the clinic. Proteomics is a global study of entire proteins of cell, tissue and organism in a particular condition and time point (Graves & Haystead, 2002). Proteomics is a very comprehensive discipline that includes the study of expression, function, localization, structure, modification, and protein-protein interaction (Graves & Haystead, 2002; Lim & ElenitobaJohnson, 2004). A proteomics experiment generates vast amount of data that require further analysis, and systems biology is the main approach. Systems biology is an integrative science that studies the complex behavior of biological entities at the systems level (Kitano, 2002a, 2002b). Integrating the proteomics data into systems biology language is an important approach in understanding the behavior of the complex organisms at various levels (Souchelnytskyi, 2005). In recent years, our knowledge of proteomics and system biology is growing rapidly and create an excitement in scientific community because of its potential in novel biomarker and drug discovery (Duncan & Hunsucker, 2005). Proteomics studies are highly dependent on the technology for protein separation and identification, and bioinformatics for data analysis. By protein separation techniques, gelbased and liquid chromatography (LC)-based approaches represent the primary stream in proteomics. In gel-based approach, that is, conventional 2D gel electrophoresis (2D-GE) and 2D differential gel electrophoresis (2D-DIGE), the proteins are separated by their molecular weight and isoelectric point. In LC-based approach, the proteins or peptides are separated by using high performance liquid chromatography (Aebersold & Mann, 2003; Cravatt et al., 2007). The identification and characterization of proteins or peptides by mass spectrometry are followed after separation (Kolker et al., 2006). In more recent years, antibody-based methods emerging as important approaches in proteomics. These approaches included the" @default.
• W1533071520 created "2016-06-24" @default.
• W1533071520 creator A5029385071 @default.
• W1533071520 creator A5033277087 @default.
• W1533071520 creator A5048176039 @default.
• W1533071520 date "2012-02-24" @default.
• W1533071520 modified "2023-09-26" @default.
• W1533071520 title "Application of Bioinformatics Tools in Gel-Based Proteomics" @default.
• W1533071520 cites W1270834676 @default.
• W1533071520 cites W1499095623 @default.
• W1533071520 cites W1597403892 @default.
• W1533071520 cites W1603786158 @default.
• W1533071520 cites W173647602 @default.
• W1533071520 cites W1898218536 @default.
• W1533071520 cites W1978486653 @default.
• W1533071520 cites W1985490978 @default.
• W1533071520 cites W1995961541 @default.
• W1533071520 cites W1996333548 @default.
• W1533071520 cites W1998902445 @default.
• W1533071520 cites W2004407704 @default.
• W1533071520 cites W2017594520 @default.
• W1533071520 cites W2018556770 @default.
• W1533071520 cites W2020515626 @default.
• W1533071520 cites W2022869269 @default.
• W1533071520 cites W2023096047 @default.
• W1533071520 cites W2032933424 @default.
• W1533071520 cites W2035719588 @default.
• W1533071520 cites W2037038488 @default.
• W1533071520 cites W2059178552 @default.
• W1533071520 cites W2061231608 @default.
• W1533071520 cites W2070834848 @default.
• W1533071520 cites W2072099326 @default.
• W1533071520 cites W2079135682 @default.
• W1533071520 cites W2085895970 @default.
• W1533071520 cites W2089149631 @default.
• W1533071520 cites W2098483742 @default.
• W1533071520 cites W2099447687 @default.
• W1533071520 cites W2099645570 @default.
• W1533071520 cites W2106552363 @default.
• W1533071520 cites W2110601338 @default.
• W1533071520 cites W2112513984 @default.
• W1533071520 cites W2113142309 @default.
• W1533071520 cites W2120774914 @default.
• W1533071520 cites W2124388496 @default.
• W1533071520 cites W2132040456 @default.
• W1533071520 cites W2132901471 @default.
• W1533071520 cites W2136609880 @default.
• W1533071520 cites W2136850043 @default.
• W1533071520 cites W2138150495 @default.
• W1533071520 cites W2138247507 @default.
• W1533071520 cites W2139084975 @default.
• W1533071520 cites W2140195921 @default.
• W1533071520 cites W2140628921 @default.
• W1533071520 cites W2141545183 @default.
• W1533071520 cites W2143081228 @default.
• W1533071520 cites W2143784594 @default.
• W1533071520 cites W2144656637 @default.
• W1533071520 cites W2145889895 @default.
• W1533071520 cites W2148115950 @default.
• W1533071520 cites W2150114991 @default.
• W1533071520 cites W2150926065 @default.
• W1533071520 cites W2153121902 @default.
• W1533071520 cites W2155142785 @default.
• W1533071520 cites W2159124857 @default.
• W1533071520 cites W2159675211 @default.
• W1533071520 cites W2159874791 @default.
• W1533071520 cites W2163480486 @default.
• W1533071520 cites W2166574880 @default.
• W1533071520 cites W2170984819 @default.
• W1533071520 cites W2180180358 @default.
• W1533071520 cites W92439441 @default.
• W1533071520 doi "https://doi.org/10.5772/31275" @default.
• W1533071520 hasPublicationYear "2012" @default.
• W1533071520 type Work @default.
• W1533071520 sameAs 1533071520 @default.
• W1533071520 citedByCount "1" @default.
• W1533071520 countsByYear W15330715202012 @default.
• W1533071520 crossrefType "book-chapter" @default.
• W1533071520 hasAuthorship W1533071520A5029385071 @default.
• W1533071520 hasAuthorship W1533071520A5033277087 @default.
• W1533071520 hasAuthorship W1533071520A5048176039 @default.
• W1533071520 hasBestOaLocation W15330715201 @default.
• W1533071520 hasConcept C104317684 @default.
• W1533071520 hasConcept C2522767166 @default.
• W1533071520 hasConcept C41008148 @default.
• W1533071520 hasConcept C46111723 @default.
• W1533071520 hasConcept C54355233 @default.
• W1533071520 hasConcept C60644358 @default.
• W1533071520 hasConcept C70721500 @default.
• W1533071520 hasConcept C86803240 @default.
• W1533071520 hasConceptScore W1533071520C104317684 @default.
• W1533071520 hasConceptScore W1533071520C2522767166 @default.
• W1533071520 hasConceptScore W1533071520C41008148 @default.
• W1533071520 hasConceptScore W1533071520C46111723 @default.
• W1533071520 hasConceptScore W1533071520C54355233 @default.
• W1533071520 hasConceptScore W1533071520C60644358 @default.
• W1533071520 hasConceptScore W1533071520C70721500 @default.
• W1533071520 hasConceptScore W1533071520C86803240 @default.
• W1533071520 hasLocation W15330715201 @default.
• W1533071520 hasLocation W15330715202 @default.

• next