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- W1533263175 abstract "Abstract Solid‐phase synthesis of 3′‐aminoalkyl, 3′‐thioalkyl, and 3′‐polyethyleneglycol are described. The first two are important as specific points of attachment for a large variety of reporter groups; the latter is important because of its increased cell membrane permeability, which aids in the development of antisense drugs. These protocols cover details of the synthetic organic chemistry needed to make each solid support, as well as DNA synthesis, workup, characterization, and conjugation." @default.
- W1533263175 created "2016-06-24" @default.
- W1533263175 creator A5078161341 @default.
- W1533263175 date "2000-12-01" @default.
- W1533263175 modified "2023-09-24" @default.
- W1533263175 title "3′‐Modified Oligonucleotides and their Conjugates" @default.
- W1533263175 cites W2005138287 @default.
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- W1533263175 doi "https://doi.org/10.1002/0471142700.nc0406s03" @default.
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