Matches in SemOpenAlex for { <https://semopenalex.org/work/W1533569738> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W1533569738 endingPage "305" @default.
- W1533569738 startingPage "297" @default.
- W1533569738 abstract "Abstract The regulation by IFN of the expression of HLA-B7 and HLA-A3 class I molecules was studied in Jurkat human T lymphoma cells, HHK EBV-transformed human B lymphocytes, and murine HLA-B7 HLA-A3 co-transfected L fibroblasts. Jurkat cells express constitutively low level of HLA class I molecules and treatment with human IFN resulted in preferential increase of the expression of HLA-B7 molecules, the expression of the HLA-A3 molecules being relatively unchanged. Similar treatment of HHK cells, which express constitutively large amount of HLA class I molecules, resulted in a marginal increase of the expression of both HLA-B7 and HLA-A3 molecules. HLA-B7 HLA-A3 co-transfected L cells express relatively low level of HLA class I molecules, expression of both however was significantly increased after treatment with murine INF-alpha, the augmentation being more accentuated for HLA-B7 molecules. In all cases, variations of cell surface expression were related to parallel modifications of the level of HLA-B7 and HLA-A3 RNA transcripts. Important nucleotide differences exist between the IFN consensus sequences associated with the HLA-B7 and HLA-A3 class I genes. Using oligonucleotides corresponding to these sequences two patterns of retarded bands were observed by the gel mobility shift assay, suggesting that the IFN-mediated differential regulation of the expression of the HLA-B7 and HLA-A3 genes could be due to different nuclear regulatory factors." @default.
- W1533569738 created "2016-06-24" @default.
- W1533569738 creator A5012375805 @default.
- W1533569738 creator A5019458378 @default.
- W1533569738 creator A5057790866 @default.
- W1533569738 creator A5067345043 @default.
- W1533569738 creator A5075685728 @default.
- W1533569738 creator A5082861587 @default.
- W1533569738 creator A5091753451 @default.
- W1533569738 date "1989-01-01" @default.
- W1533569738 modified "2023-10-18" @default.
- W1533569738 title "IFN-mediated differential regulation of the expression of HLA-B7 and HLA-A3 class I genes." @default.
- W1533569738 doi "https://doi.org/10.4049/jimmunol.142.1.297" @default.
- W1533569738 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2535859" @default.
- W1533569738 hasPublicationYear "1989" @default.
- W1533569738 type Work @default.
- W1533569738 sameAs 1533569738 @default.
- W1533569738 citedByCount "32" @default.
- W1533569738 countsByYear W15335697382021 @default.
- W1533569738 crossrefType "journal-article" @default.
- W1533569738 hasAuthorship W1533569738A5012375805 @default.
- W1533569738 hasAuthorship W1533569738A5019458378 @default.
- W1533569738 hasAuthorship W1533569738A5057790866 @default.
- W1533569738 hasAuthorship W1533569738A5067345043 @default.
- W1533569738 hasAuthorship W1533569738A5075685728 @default.
- W1533569738 hasAuthorship W1533569738A5082861587 @default.
- W1533569738 hasAuthorship W1533569738A5091753451 @default.
- W1533569738 hasBestOaLocation W15335697381 @default.
- W1533569738 hasConcept C104317684 @default.
- W1533569738 hasConcept C147483822 @default.
- W1533569738 hasConcept C153911025 @default.
- W1533569738 hasConcept C179464577 @default.
- W1533569738 hasConcept C188280979 @default.
- W1533569738 hasConcept C203014093 @default.
- W1533569738 hasConcept C2775866039 @default.
- W1533569738 hasConcept C2776090121 @default.
- W1533569738 hasConcept C54009773 @default.
- W1533569738 hasConcept C54355233 @default.
- W1533569738 hasConcept C86803240 @default.
- W1533569738 hasConcept C8891405 @default.
- W1533569738 hasConcept C95444343 @default.
- W1533569738 hasConceptScore W1533569738C104317684 @default.
- W1533569738 hasConceptScore W1533569738C147483822 @default.
- W1533569738 hasConceptScore W1533569738C153911025 @default.
- W1533569738 hasConceptScore W1533569738C179464577 @default.
- W1533569738 hasConceptScore W1533569738C188280979 @default.
- W1533569738 hasConceptScore W1533569738C203014093 @default.
- W1533569738 hasConceptScore W1533569738C2775866039 @default.
- W1533569738 hasConceptScore W1533569738C2776090121 @default.
- W1533569738 hasConceptScore W1533569738C54009773 @default.
- W1533569738 hasConceptScore W1533569738C54355233 @default.
- W1533569738 hasConceptScore W1533569738C86803240 @default.
- W1533569738 hasConceptScore W1533569738C8891405 @default.
- W1533569738 hasConceptScore W1533569738C95444343 @default.
- W1533569738 hasIssue "1" @default.
- W1533569738 hasLocation W15335697381 @default.
- W1533569738 hasLocation W15335697382 @default.
- W1533569738 hasOpenAccess W1533569738 @default.
- W1533569738 hasPrimaryLocation W15335697381 @default.
- W1533569738 hasRelatedWork W2002647387 @default.
- W1533569738 hasRelatedWork W2011936762 @default.
- W1533569738 hasRelatedWork W2038338133 @default.
- W1533569738 hasRelatedWork W2050042904 @default.
- W1533569738 hasRelatedWork W2205639878 @default.
- W1533569738 hasRelatedWork W2509726029 @default.
- W1533569738 hasRelatedWork W2601749131 @default.
- W1533569738 hasRelatedWork W2625783584 @default.
- W1533569738 hasRelatedWork W3028961804 @default.
- W1533569738 hasRelatedWork W4241627343 @default.
- W1533569738 hasVolume "142" @default.
- W1533569738 isParatext "false" @default.
- W1533569738 isRetracted "false" @default.
- W1533569738 magId "1533569738" @default.
- W1533569738 workType "article" @default.