Matches in SemOpenAlex for { <https://semopenalex.org/work/W1533635046> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W1533635046 endingPage "1054" @default.
- W1533635046 startingPage "1050" @default.
- W1533635046 abstract "Abstract Detachment of individual sickle erythrocytes from cultured endothelial cell monolayers has been evaluated by a fluid-shearing technique in an effort to quantitate adherence at shear forces that would be anticipated in the in vivo circulation. Nonirreversibly sickled cells (non-ISC) were more adherent at normal oxygen tensions than control cells. More than 1% non-ISC remained attached to the monolayer at forces greater than physiologic shear stresses in capillary and venous circulations, and many of the most avidly attached cells, once separated, immediately reattached to adjacent endothelial cells. These data suggest that hemoglobin S-containing erythrocytes may have a higher frequency of adherence in vivo in regions of low shear stress where prolonged erythrocyte-endothelial cell contact could occur. Some of these cells detached by shear force would subsequently reattach in in vivo conditions. Plasma-enhanced attachment frequency and plasma from blood in a case of sickle crisis caused further increase. These observations further support the concept that sickle erythrocyte- endothelial cell interaction may be a significant factor in initiation of vascular occlusive events in sickle cell disease." @default.
- W1533635046 created "2016-06-24" @default.
- W1533635046 creator A5012102864 @default.
- W1533635046 creator A5059680271 @default.
- W1533635046 date "1986-11-01" @default.
- W1533635046 modified "2023-10-01" @default.
- W1533635046 title "Erythrocyte-endothelial cell adherence in sickle cell disorders" @default.
- W1533635046 cites W150232704 @default.
- W1533635046 cites W1540490820 @default.
- W1533635046 cites W185988186 @default.
- W1533635046 cites W1969617897 @default.
- W1533635046 cites W1989254461 @default.
- W1533635046 cites W1992575642 @default.
- W1533635046 cites W2012020611 @default.
- W1533635046 cites W2062090472 @default.
- W1533635046 cites W2083399493 @default.
- W1533635046 cites W2102715003 @default.
- W1533635046 cites W2118537375 @default.
- W1533635046 cites W2129241682 @default.
- W1533635046 cites W2135877291 @default.
- W1533635046 cites W2163565535 @default.
- W1533635046 cites W2220235296 @default.
- W1533635046 cites W2303129106 @default.
- W1533635046 cites W247120043 @default.
- W1533635046 cites W2507069233 @default.
- W1533635046 cites W2414040492 @default.
- W1533635046 doi "https://doi.org/10.1182/blood.v68.5.1050.1050" @default.
- W1533635046 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3768530" @default.
- W1533635046 hasPublicationYear "1986" @default.
- W1533635046 type Work @default.
- W1533635046 sameAs 1533635046 @default.
- W1533635046 citedByCount "44" @default.
- W1533635046 countsByYear W15336350462016 @default.
- W1533635046 countsByYear W15336350462019 @default.
- W1533635046 crossrefType "journal-article" @default.
- W1533635046 hasAuthorship W1533635046A5012102864 @default.
- W1533635046 hasAuthorship W1533635046A5059680271 @default.
- W1533635046 hasBestOaLocation W15336350461 @default.
- W1533635046 hasConcept C123012128 @default.
- W1533635046 hasConcept C126322002 @default.
- W1533635046 hasConcept C1491633281 @default.
- W1533635046 hasConcept C150903083 @default.
- W1533635046 hasConcept C185592680 @default.
- W1533635046 hasConcept C202751555 @default.
- W1533635046 hasConcept C203014093 @default.
- W1533635046 hasConcept C207001950 @default.
- W1533635046 hasConcept C2776992346 @default.
- W1533635046 hasConcept C2777208419 @default.
- W1533635046 hasConcept C2778620579 @default.
- W1533635046 hasConcept C2778917026 @default.
- W1533635046 hasConcept C55493867 @default.
- W1533635046 hasConcept C71924100 @default.
- W1533635046 hasConcept C86803240 @default.
- W1533635046 hasConceptScore W1533635046C123012128 @default.
- W1533635046 hasConceptScore W1533635046C126322002 @default.
- W1533635046 hasConceptScore W1533635046C1491633281 @default.
- W1533635046 hasConceptScore W1533635046C150903083 @default.
- W1533635046 hasConceptScore W1533635046C185592680 @default.
- W1533635046 hasConceptScore W1533635046C202751555 @default.
- W1533635046 hasConceptScore W1533635046C203014093 @default.
- W1533635046 hasConceptScore W1533635046C207001950 @default.
- W1533635046 hasConceptScore W1533635046C2776992346 @default.
- W1533635046 hasConceptScore W1533635046C2777208419 @default.
- W1533635046 hasConceptScore W1533635046C2778620579 @default.
- W1533635046 hasConceptScore W1533635046C2778917026 @default.
- W1533635046 hasConceptScore W1533635046C55493867 @default.
- W1533635046 hasConceptScore W1533635046C71924100 @default.
- W1533635046 hasConceptScore W1533635046C86803240 @default.
- W1533635046 hasIssue "5" @default.
- W1533635046 hasLocation W15336350461 @default.
- W1533635046 hasOpenAccess W1533635046 @default.
- W1533635046 hasPrimaryLocation W15336350461 @default.
- W1533635046 hasRelatedWork W1533635046 @default.
- W1533635046 hasRelatedWork W1577608867 @default.
- W1533635046 hasRelatedWork W1991921762 @default.
- W1533635046 hasRelatedWork W2008680645 @default.
- W1533635046 hasRelatedWork W2028611848 @default.
- W1533635046 hasRelatedWork W2064500426 @default.
- W1533635046 hasRelatedWork W2131975330 @default.
- W1533635046 hasRelatedWork W2333684468 @default.
- W1533635046 hasRelatedWork W4232447928 @default.
- W1533635046 hasRelatedWork W4232985767 @default.
- W1533635046 hasVolume "68" @default.
- W1533635046 isParatext "false" @default.
- W1533635046 isRetracted "false" @default.
- W1533635046 magId "1533635046" @default.
- W1533635046 workType "article" @default.