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- W1534302016 abstract "Croton oil is known to contain a potent tumour-promoting factor, 12-O-tetradecanoylphorbol 13-acetate (TPA), which is responsible for generation of oxygen free radicals and in turn the free radicals lead to lipid peroxidation. Such lipid peroxidation is assumed to induce severe inflammatory changes, increased vascular permeability and generation of proinflammatory hydroperoxides. Commonly used antioxidants are known to inhibit TPA. Our earlier results obtained from studies with Pluchea indica indicated that the methanolic fraction of the root extract possess significant anti-inflammatory and antioxidant activity.The present study was designed to assess the degree of inhibitory effect of P. indica on croton oil-induced mouse ear oedema, lipid hydroperoxide formation, peroxidizability of the epidermal layer and also in-vitro lipid peroxidation (using FeCl3/ADP/NADPH and CCl4 systems)." @default.
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- W1534302016 date "1996-09-01" @default.
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- W1534302016 title "Studies on the Methanolic Fraction of Pluchea indica on Croton Oil-induced Mouse Ear Oedema and Lipid Peroxidation" @default.
- W1534302016 doi "https://doi.org/10.1111/j.2042-7158.1996.tb00650.x" @default.
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