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- W1534692007 abstract "The influence of chronic energy intake restriction (CEIR) on the level and activity of intestinal alkaline phosphatase was investigated in mice of the autoimmuneprone MRL/lpr,lpr strain and in mice of the autoimmune-resistant C3H/Bi strain. In both strains of mice, CEIR of 40% resulted in a significant increase in intestinal alkaline phosphatase (IAP) specific activity in MRL/lpr,lpr mice after 10 wk of feeding, and in C3H/Bi mice after 6 wk of feeding. An increase in the amount of immunoreactive alkaline phosphatase antigen was also found to be associated with the increased enzyme activity in CEIR mice. These results suggest that a specific induction of an intestinal enzyme occurs or, alternatively, that there is a specific relative decrease in synthesis of intestinal proteins other than IAP as a function of CEIR. Thus, CEIR appears to regulate the expression of proteins in the small intestine in a specific manner." @default.
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- W1534692007 date "1989-12-01" @default.
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- W1534692007 title "Influence of Chronic Energy Intake Restriction on Intestinal Alkaline Phosphatase in C3H/Bi Mice and Autoimmune-Prone MRL/lpr,lpr Mice" @default.
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- W1534692007 doi "https://doi.org/10.1093/jn/119.12.2017" @default.
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