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• W1534698081 endingPage "3247" @default.
• W1534698081 startingPage "3235" @default.
• W1534698081 abstract "Two theories explain how negative mood primes smoking behaviour. The stimulus-response (S-R) account argues that in the negative mood state, smoking is experienced as more reinforcing, establishing a direct (automatic) association between the negative mood state and smoking behaviour. By contrast, the incentive learning account argues that in the negative mood state smoking is expected to be more reinforcing, which integrates with instrumental knowledge of the response required to produce that outcome.One differential prediction is that whereas the incentive learning account anticipates that negative mood induction could augment a novel tobacco-seeking response in an extinction test, the S-R account could not explain this effect because the extinction test prevents S-R learning by omitting experience of the reinforcer.To test this, overnight-deprived daily smokers (n = 44) acquired two instrumental responses for tobacco and chocolate points, respectively, before smoking to satiety. Half then received negative mood induction to raise the expected value of tobacco, opposing satiety, whilst the remainder received positive mood induction. Finally, a choice between tobacco and chocolate was measured in extinction to test whether negative mood could augment tobacco choice, opposing satiety, in the absence of direct experience of tobacco reinforcement.Negative mood induction not only abolished the devaluation of tobacco choice, but participants with a significant increase in negative mood increased their tobacco choice in extinction, despite satiety.These findings suggest that negative mood augments drug-seeking by raising the expected value of the drug through incentive learning, rather than through automatic S-R control." @default.
• W1534698081 created "2016-06-24" @default.
• W1534698081 creator A5022642097 @default.
• W1534698081 creator A5036557152 @default.
• W1534698081 creator A5037419542 @default.
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• W1534698081 creator A5068168765 @default.
• W1534698081 creator A5073475150 @default.
• W1534698081 creator A5079095299 @default.
• W1534698081 creator A5085270426 @default.
• W1534698081 date "2015-06-05" @default.
• W1534698081 modified "2023-10-16" @default.
• W1534698081 title "Negative mood reverses devaluation of goal-directed drug-seeking favouring an incentive learning account of drug dependence" @default.
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