FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1534779938> ?p ?o ?g. }

• W1534779938 endingPage "140" @default.
• W1534779938 startingPage "134" @default.
• W1534779938 abstract "A fragment of Bacillus plasmid pAB124 carrying the genes encoding tetracycline resistance was previously cloned into Escherichia coli plasmid pSF2124 (S.J. Eccles, A. Docherty, I. Chopra, S. Shales, and P. Ball, J. Bacteriol. 145:1417-1420, 1981). The cloned pAB124 tet fragment conferred low-level resistance in E. coli, but exposure of this strain to a subinhibitory level of tetracycline led to selection of a mutant plasmid in which high-level resistance, associated with decreased drug accumulation, was expressed constitutively. In this plasmid, the Bacillus tet determinant appeared to be transcribed from a promoter on the vector. Construction of tetracycline-sensitive derivatives of this plasmid by transposon insertion mutagenesis allowed identification of a 32,000-dalton membrane-located protein, which apparently promoted decreased accumulation of tetracycline. This protein was also synthesized as a 32,000-dalton polypeptide in a coupled, in vitro transcription-translation system directed by plasmid DNA. The pAB124 tet determinant differed from the tetA through tetD determinants found in gram-negative bacteria in DNA-DNA hybridization and in the ability to prevent accumulation of different tetracycline derivatives, but was closely related to the tet determinant of another plasmid isolated from Bacillus species, pBC16." @default.
• W1534779938 created "2016-06-24" @default.
• W1534779938 creator A5044018267 @default.
• W1534779938 creator A5050779833 @default.
• W1534779938 date "1984-04-01" @default.
• W1534779938 modified "2023-10-18" @default.
• W1534779938 title "Biochemical and genetic characterization of the tet determinant of Bacillus plasmid pAB124" @default.
• W1534779938 cites W1419303435 @default.
• W1534779938 cites W1484403996 @default.
• W1534779938 cites W1600545693 @default.
• W1534779938 cites W1766411435 @default.
• W1534779938 cites W1861767839 @default.
• W1534779938 cites W1968800713 @default.
• W1534779938 cites W1970081885 @default.
• W1534779938 cites W1974596559 @default.
• W1534779938 cites W1976701127 @default.
• W1534779938 cites W1999144025 @default.
• W1534779938 cites W2000284372 @default.
• W1534779938 cites W2013467803 @default.
• W1534779938 cites W2014141735 @default.
• W1534779938 cites W2026604094 @default.
• W1534779938 cites W2028030581 @default.
• W1534779938 cites W2035753192 @default.
• W1534779938 cites W2037192566 @default.
• W1534779938 cites W2043317881 @default.
• W1534779938 cites W2052574741 @default.
• W1534779938 cites W2055003474 @default.
• W1534779938 cites W2061096025 @default.
• W1534779938 cites W2063450941 @default.
• W1534779938 cites W2069687704 @default.
• W1534779938 cites W2074476437 @default.
• W1534779938 cites W2077703362 @default.
• W1534779938 cites W2100837269 @default.
• W1534779938 cites W2337667589 @default.
• W1534779938 cites W40853052 @default.
• W1534779938 doi "https://doi.org/10.1128/jb.158.1.134-140.1984" @default.
• W1534779938 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/215390" @default.
• W1534779938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6325384" @default.
• W1534779938 hasPublicationYear "1984" @default.
• W1534779938 type Work @default.
• W1534779938 sameAs 1534779938 @default.
• W1534779938 citedByCount "14" @default.
• W1534779938 countsByYear W15347799382020 @default.
• W1534779938 countsByYear W15347799382022 @default.
• W1534779938 crossrefType "journal-article" @default.
• W1534779938 hasAuthorship W1534779938A5044018267 @default.
• W1534779938 hasAuthorship W1534779938A5050779833 @default.
• W1534779938 hasBestOaLocation W15347799381 @default.
• W1534779938 hasConcept C104317684 @default.
• W1534779938 hasConcept C109932267 @default.
• W1534779938 hasConcept C143065580 @default.
• W1534779938 hasConcept C150194340 @default.
• W1534779938 hasConcept C153911025 @default.
• W1534779938 hasConcept C158448853 @default.
• W1534779938 hasConcept C205225487 @default.
• W1534779938 hasConcept C22744801 @default.
• W1534779938 hasConcept C2777274385 @default.
• W1534779938 hasConcept C2780242733 @default.
• W1534779938 hasConcept C2780923616 @default.
• W1534779938 hasConcept C4918238 @default.
• W1534779938 hasConcept C501593827 @default.
• W1534779938 hasConcept C54355233 @default.
• W1534779938 hasConcept C547475151 @default.
• W1534779938 hasConcept C552990157 @default.
• W1534779938 hasConcept C86803240 @default.
• W1534779938 hasConcept C89423630 @default.
• W1534779938 hasConceptScore W1534779938C104317684 @default.
• W1534779938 hasConceptScore W1534779938C109932267 @default.
• W1534779938 hasConceptScore W1534779938C143065580 @default.
• W1534779938 hasConceptScore W1534779938C150194340 @default.
• W1534779938 hasConceptScore W1534779938C153911025 @default.
• W1534779938 hasConceptScore W1534779938C158448853 @default.
• W1534779938 hasConceptScore W1534779938C205225487 @default.
• W1534779938 hasConceptScore W1534779938C22744801 @default.
• W1534779938 hasConceptScore W1534779938C2777274385 @default.
• W1534779938 hasConceptScore W1534779938C2780242733 @default.
• W1534779938 hasConceptScore W1534779938C2780923616 @default.
• W1534779938 hasConceptScore W1534779938C4918238 @default.
• W1534779938 hasConceptScore W1534779938C501593827 @default.
• W1534779938 hasConceptScore W1534779938C54355233 @default.
• W1534779938 hasConceptScore W1534779938C547475151 @default.
• W1534779938 hasConceptScore W1534779938C552990157 @default.
• W1534779938 hasConceptScore W1534779938C86803240 @default.
• W1534779938 hasConceptScore W1534779938C89423630 @default.
• W1534779938 hasIssue "1" @default.
• W1534779938 hasLocation W15347799381 @default.
• W1534779938 hasLocation W15347799382 @default.
• W1534779938 hasLocation W15347799383 @default.
• W1534779938 hasOpenAccess W1534779938 @default.
• W1534779938 hasPrimaryLocation W15347799381 @default.
• W1534779938 hasRelatedWork W1496454862 @default.
• W1534779938 hasRelatedWork W1534779938 @default.
• W1534779938 hasRelatedWork W1558647939 @default.
• W1534779938 hasRelatedWork W1831836912 @default.
• W1534779938 hasRelatedWork W1987310873 @default.
• W1534779938 hasRelatedWork W1993000734 @default.
• W1534779938 hasRelatedWork W2086404593 @default.
• W1534779938 hasRelatedWork W2103849003 @default.

• next