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- W153484311 abstract "The vast majority of hematologic malignancies are clinically, prognostically, and genetically complex diseases. High-throughput gene expression studies, coupled with analysis of copy number alterations, directed sequencing, and functional assays provided the “bird’s eye view” on the tumor cell and its environment and greatly advanced the level of understanding of these tumors. In this chapter, we discuss the technical aspects of gene-expression profiling experiments, and review the results of major studies on lymphoid and myeloid leukemias and myelodysplastic syndromes that changed our understanding of these diseases. We also present translational and diagnostic implications of recent studies performed with the gene expression profiling platforms." @default.
- W153484311 created "2016-06-24" @default.
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- W153484311 date "2012-01-01" @default.
- W153484311 modified "2023-10-12" @default.
- W153484311 title "Gene Expression Profiling in Hematologic Malignancies" @default.
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- W153484311 doi "https://doi.org/10.1007/978-3-642-29467-9_12" @default.
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