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- W1534854101 endingPage "3776" @default.
- W1534854101 startingPage "3765" @default.
- W1534854101 abstract "Multiple myeloma is a neoplastic disorder of plasma cells characterized by clonal proliferation within the bone marrow. One of the major clinical features of multiple myeloma is the destructive osteolytic bone disease that occurs in the majority of patients. Myeloma bone disease is associated with increased osteoclast activity and suppression of osteoblastogenesis. Bisphosphonates have been the mainstay of treatment for many years; however, their use is limited by their inability to repair existing bone loss. Therefore, research into novel approaches for the treatment of myeloma bone disease is of the utmost importance. This review will discuss the current advances in our understanding of osteoclast stimulation and osteoblast suppression mechanisms in myeloma bone disease and the treatments that are under development to target this destructive and debilitating feature of myeloma." @default.
- W1534854101 created "2016-06-24" @default.
- W1534854101 creator A5034047848 @default.
- W1534854101 creator A5083463594 @default.
- W1534854101 date "2014-07-25" @default.
- W1534854101 modified "2023-10-12" @default.
- W1534854101 title "Novel therapeutic targets in myeloma bone disease" @default.
- W1534854101 cites W1491413470 @default.
- W1534854101 cites W1506777188 @default.
- W1534854101 cites W1516916106 @default.
- W1534854101 cites W1534557867 @default.
- W1534854101 cites W1534645474 @default.
- W1534854101 cites W1557541313 @default.
- W1534854101 cites W1589352523 @default.
- W1534854101 cites W1671698008 @default.
- W1534854101 cites W1751306081 @default.
- W1534854101 cites W1842497498 @default.
- W1534854101 cites W1844361913 @default.
- W1534854101 cites W1905245397 @default.
- W1534854101 cites W192473290 @default.
- W1534854101 cites W1965774172 @default.
- W1534854101 cites W1968089570 @default.
- W1534854101 cites W1968544465 @default.
- W1534854101 cites W1972232704 @default.
- W1534854101 cites W1972705137 @default.
- W1534854101 cites W1973328408 @default.
- W1534854101 cites W1973701188 @default.
- W1534854101 cites W1974602537 @default.
- W1534854101 cites W1975953388 @default.
- W1534854101 cites W1981916517 @default.
- W1534854101 cites W1983220846 @default.
- W1534854101 cites W1984534203 @default.
- W1534854101 cites W1990781364 @default.
- W1534854101 cites W1992826431 @default.
- W1534854101 cites W1994476823 @default.
- W1534854101 cites W1996228981 @default.
- W1534854101 cites W1996717896 @default.
- W1534854101 cites W1997686829 @default.
- W1534854101 cites W1997952190 @default.
- W1534854101 cites W1998854709 @default.
- W1534854101 cites W1999077925 @default.
- W1534854101 cites W2000647744 @default.
- W1534854101 cites W2001718824 @default.
- W1534854101 cites W2002918019 @default.
- W1534854101 cites W2003164049 @default.
- W1534854101 cites W2003457351 @default.
- W1534854101 cites W2006778528 @default.
- W1534854101 cites W2007603569 @default.
- W1534854101 cites W2007793077 @default.
- W1534854101 cites W2010552629 @default.
- W1534854101 cites W2010999937 @default.
- W1534854101 cites W2011557716 @default.
- W1534854101 cites W2013296669 @default.
- W1534854101 cites W2017682198 @default.
- W1534854101 cites W2021829493 @default.
- W1534854101 cites W2025672197 @default.
- W1534854101 cites W2026387061 @default.
- W1534854101 cites W2031207391 @default.
- W1534854101 cites W2031314023 @default.
- W1534854101 cites W2031812779 @default.
- W1534854101 cites W2032434507 @default.
- W1534854101 cites W2032956576 @default.
- W1534854101 cites W2034825504 @default.
- W1534854101 cites W2037110510 @default.
- W1534854101 cites W2038063884 @default.
- W1534854101 cites W2039215669 @default.
- W1534854101 cites W2040400629 @default.
- W1534854101 cites W2044264310 @default.
- W1534854101 cites W2044835347 @default.
- W1534854101 cites W2045540294 @default.
- W1534854101 cites W2047650149 @default.
- W1534854101 cites W2048299560 @default.
- W1534854101 cites W2048981489 @default.
- W1534854101 cites W2050080529 @default.
- W1534854101 cites W2055167990 @default.
- W1534854101 cites W2055966182 @default.
- W1534854101 cites W2056442040 @default.
- W1534854101 cites W2058580930 @default.
- W1534854101 cites W2059860426 @default.
- W1534854101 cites W2063854993 @default.
- W1534854101 cites W2064539228 @default.
- W1534854101 cites W2066000727 @default.
- W1534854101 cites W2067594973 @default.
- W1534854101 cites W2068076832 @default.
- W1534854101 cites W2071565020 @default.
- W1534854101 cites W2077015738 @default.
- W1534854101 cites W2078400068 @default.
- W1534854101 cites W2078493291 @default.
- W1534854101 cites W2080709390 @default.
- W1534854101 cites W2084400611 @default.
- W1534854101 cites W2086216113 @default.
- W1534854101 cites W2088023367 @default.
- W1534854101 cites W2088317099 @default.
- W1534854101 cites W2091514824 @default.
- W1534854101 cites W2092758964 @default.
- W1534854101 cites W2095098163 @default.
- W1534854101 cites W2096315312 @default.
- W1534854101 cites W2096627331 @default.