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- W1535157049 abstract "In recent years, several natural products containing 2,4-disubstituted oxazoles have been isolated and their synthetic routes were investigated. Several key intermediates required for the synthesis of target compounds were achieved via the Stille, Suzuki, Heck, and Sonogashira reactions. In addition, several 2,5-diaryloxzoles were prepared from 2-halo-5-aryloxazoles via the Suzuki coupling. These coupling reactions enabled manipulation and elaboration of the functional groups further in the 2,4-disubstituted oxazoles system to more useful synthetic intermediates. Oxazol-2-ylzinc chloride reagents can be pre-pared from the transmetalation of oxazol-2-yllithium with ZnCl2 , whereas oxazol-2-ylboronic acid is unprecedented. Stannyloxazoles are readily prepared and the Stille reaction is still the method of choice for synthesizing oxazole-containing molecules if the toxicity is not of great concern. 4-Bromo- and 5-bromo-4-methyloxazoles are viable sub-strates for both the Sonogashira and Heck reactions. The heteroaryl Heck reaction using oxazole as a recipient partner takes place predominantly at the electron-rich position C(5), whereas it occurs at C(2) for benzoxazole." @default.
- W1535157049 created "2016-06-24" @default.
- W1535157049 creator A5054412733 @default.
- W1535157049 date "2007-01-01" @default.
- W1535157049 modified "2023-10-18" @default.
- W1535157049 title "Chapter 8 Oxazoles and benzoxazoles" @default.
- W1535157049 cites W1966777802 @default.
- W1535157049 cites W1973084543 @default.
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- W1535157049 cites W1977790452 @default.
- W1535157049 cites W1987278262 @default.
- W1535157049 cites W1989139206 @default.
- W1535157049 cites W2006780600 @default.
- W1535157049 cites W2007765539 @default.
- W1535157049 cites W2009437293 @default.
- W1535157049 cites W2010673784 @default.
- W1535157049 cites W2022955258 @default.
- W1535157049 cites W2023000799 @default.
- W1535157049 cites W2027316605 @default.
- W1535157049 cites W2027549434 @default.
- W1535157049 cites W2032424355 @default.
- W1535157049 cites W2034374709 @default.
- W1535157049 cites W2036686323 @default.
- W1535157049 cites W2041938066 @default.
- W1535157049 cites W2044485322 @default.
- W1535157049 cites W2049046319 @default.
- W1535157049 cites W2051418103 @default.
- W1535157049 cites W2053823863 @default.
- W1535157049 cites W2067871153 @default.
- W1535157049 cites W2068454124 @default.
- W1535157049 cites W2069093734 @default.
- W1535157049 cites W2070061941 @default.
- W1535157049 cites W2078044408 @default.
- W1535157049 cites W2085887479 @default.
- W1535157049 cites W2087279809 @default.
- W1535157049 cites W2088092009 @default.
- W1535157049 cites W2088424662 @default.
- W1535157049 cites W2089792210 @default.
- W1535157049 cites W2090268067 @default.
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- W1535157049 cites W2112822872 @default.
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- W1535157049 cites W2124375898 @default.
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- W1535157049 cites W2952805166 @default.
- W1535157049 cites W2952864159 @default.
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- W1535157049 doi "https://doi.org/10.1016/s1460-1567(07)80057-2" @default.
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