FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1535652773> ?p ?o ?g. }

• W1535652773 abstract "Abstract Background On porcine chromosome 7, the region surrounding the Major Histocompatibility Complex (MHC) contains several Quantitative Trait Loci (QTL) influencing many traits including growth, back fat thickness and carcass composition. Previous studies highlighted that a fragment of ~3.7 Mb is located within the Swine Leucocyte Antigen (SLA) complex. Internal rearrangements of this fragment were suggested, and partial contigs had been built, but further characterization of this region and identification of all human chromosomal fragments orthologous to this porcine fragment had to be carried out. Results A whole physical map of the region was constructed by integrating Radiation Hybrid (RH) mapping, BAC fingerprinting data of the INRA BAC library and anchoring BAC end sequences on the human genome. 17 genes and 2 reference microsatellites were ordered on the high resolution IMNpRH2 12000rad Radiation Hybrid panel. A 1000:1 framework map covering 550 cR 12000 was established and a complete contig of the region was developed. New micro rearrangements were highlighted between the porcine and human genomes. A bovine RH map was also developed in this region by mapping 16 genes. Comparison of the organization of this region in pig, cattle, human, mouse, dog and chicken genomes revealed that 1) the translocation of the fragment described previously is observed only on the bovine and porcine genomes and 2) the new internal micro rearrangements are specific of the porcine genome. Conclusion We estimate that the region contains several rearrangements and covers 5.2 Mb of the porcine genome. The study of this complete BAC contig showed that human chromosomal fragments homologs of this heavily rearranged QTL region are all located in the region of HSA6 that surrounds the centromere. This work allows us to define a list of all candidate genes that could explain these QTL effects." @default.
• W1535652773 created "2016-06-24" @default.
• W1535652773 creator A5004282282 @default.
• W1535652773 creator A5030799587 @default.
• W1535652773 creator A5043765934 @default.
• W1535652773 creator A5046730361 @default.
• W1535652773 creator A5057512395 @default.
• W1535652773 creator A5076682143 @default.
• W1535652773 creator A5080177497 @default.
• W1535652773 creator A5084261960 @default.
• W1535652773 creator A5084849751 @default.
• W1535652773 date "2006-01-24" @default.
• W1535652773 modified "2023-10-15" @default.
• W1535652773 title "High resolution physical map of porcine chromosome 7 QTL region and comparative mapping of this region among vertebrate genomes" @default.
• W1535652773 cites W1526802041 @default.
• W1535652773 cites W1634772899 @default.
• W1535652773 cites W1967841809 @default.
• W1535652773 cites W1971926406 @default.
• W1535652773 cites W1999169677 @default.
• W1535652773 cites W2007684969 @default.
• W1535652773 cites W2011504026 @default.
• W1535652773 cites W2026609789 @default.
• W1535652773 cites W2035625064 @default.
• W1535652773 cites W2038574100 @default.
• W1535652773 cites W2054114475 @default.
• W1535652773 cites W2056332505 @default.
• W1535652773 cites W2063166652 @default.
• W1535652773 cites W2077934061 @default.
• W1535652773 cites W2080573367 @default.
• W1535652773 cites W2087271551 @default.
• W1535652773 cites W2088522679 @default.
• W1535652773 cites W2090130549 @default.
• W1535652773 cites W2099238965 @default.
• W1535652773 cites W2109258478 @default.
• W1535652773 cites W2112562553 @default.
• W1535652773 cites W2113368564 @default.
• W1535652773 cites W2133090982 @default.
• W1535652773 cites W2139505478 @default.
• W1535652773 cites W2143420603 @default.
• W1535652773 cites W2145516868 @default.
• W1535652773 cites W2146733850 @default.
• W1535652773 cites W2158209548 @default.
• W1535652773 cites W2158717226 @default.
• W1535652773 cites W2159456332 @default.
• W1535652773 cites W2164031281 @default.
• W1535652773 cites W4238092255 @default.
• W1535652773 cites W47407007 @default.
• W1535652773 doi "https://doi.org/10.1186/1471-2164-7-13" @default.
• W1535652773 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1420295" @default.
• W1535652773 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16433907" @default.
• W1535652773 hasPublicationYear "2006" @default.
• W1535652773 type Work @default.
• W1535652773 sameAs 1535652773 @default.
• W1535652773 citedByCount "22" @default.
• W1535652773 countsByYear W15356527732012 @default.
• W1535652773 countsByYear W15356527732013 @default.
• W1535652773 countsByYear W15356527732015 @default.
• W1535652773 countsByYear W15356527732018 @default.
• W1535652773 crossrefType "journal-article" @default.
• W1535652773 hasAuthorship W1535652773A5004282282 @default.
• W1535652773 hasAuthorship W1535652773A5030799587 @default.
• W1535652773 hasAuthorship W1535652773A5043765934 @default.
• W1535652773 hasAuthorship W1535652773A5046730361 @default.
• W1535652773 hasAuthorship W1535652773A5057512395 @default.
• W1535652773 hasAuthorship W1535652773A5076682143 @default.
• W1535652773 hasAuthorship W1535652773A5080177497 @default.
• W1535652773 hasAuthorship W1535652773A5084261960 @default.
• W1535652773 hasAuthorship W1535652773A5084849751 @default.
• W1535652773 hasBestOaLocation W15356527731 @default.
• W1535652773 hasConcept C104317684 @default.
• W1535652773 hasConcept C122735190 @default.
• W1535652773 hasConcept C141231307 @default.
• W1535652773 hasConcept C180754005 @default.
• W1535652773 hasConcept C182901222 @default.
• W1535652773 hasConcept C192953774 @default.
• W1535652773 hasConcept C2776473694 @default.
• W1535652773 hasConcept C2777714445 @default.
• W1535652773 hasConcept C30481170 @default.
• W1535652773 hasConcept C54355233 @default.
• W1535652773 hasConcept C59582021 @default.
• W1535652773 hasConcept C61320498 @default.
• W1535652773 hasConcept C70721500 @default.
• W1535652773 hasConcept C81941488 @default.
• W1535652773 hasConcept C86803240 @default.
• W1535652773 hasConcept C89566754 @default.
• W1535652773 hasConceptScore W1535652773C104317684 @default.
• W1535652773 hasConceptScore W1535652773C122735190 @default.
• W1535652773 hasConceptScore W1535652773C141231307 @default.
• W1535652773 hasConceptScore W1535652773C180754005 @default.
• W1535652773 hasConceptScore W1535652773C182901222 @default.
• W1535652773 hasConceptScore W1535652773C192953774 @default.
• W1535652773 hasConceptScore W1535652773C2776473694 @default.
• W1535652773 hasConceptScore W1535652773C2777714445 @default.
• W1535652773 hasConceptScore W1535652773C30481170 @default.
• W1535652773 hasConceptScore W1535652773C54355233 @default.
• W1535652773 hasConceptScore W1535652773C59582021 @default.
• W1535652773 hasConceptScore W1535652773C61320498 @default.
• W1535652773 hasConceptScore W1535652773C70721500 @default.
• W1535652773 hasConceptScore W1535652773C81941488 @default.
• W1535652773 hasConceptScore W1535652773C86803240 @default.

• next