FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1535818125> ?p ?o ?g. }

• W1535818125 endingPage "2092" @default.
• W1535818125 startingPage "2088" @default.
• W1535818125 abstract "The assembly process of poliovirus occurs via an ordered proteolytic processing of the capsid precursor protein, P1, by the virus-encoded proteinase 3CD. To further delineate this process, we have isolated a recombinant vaccinia virus which expresses, upon infection, the poliovirus P1 capsid precursor polyprotein with an authentic carboxy terminus. Coinfection of HeLa cells with the P1-expressing vaccinia virus and with a second recombinant vaccinia virus which expresses the poliovirus proteinase 3CD resulted in the correct processing of P1 to yield the three individual capsid proteins VP0, VP3, and VP1. When extracts from coinfected cells were fractionated on sucrose density gradients, the VP0, VP3, and VP1 capsid proteins were immunoprecipitated with type 1 poliovirus antisera from fractions corresponding to a sedimentation consistent for poliovirus 75S procapsids. Examination of these fractions by electron microscopy revealed structures which lacked electron-dense cores and which corresponded in size and shape to those expected for poliovirus empty capsids. We conclude that the expression of the two poliovirus proteins P1 and 3CD in coinfected cells is sufficient for the correct processing of the capsid precursor to VP0, VP3, and VP1 as well as for the assembly of poliovirus empty capsid-like structures." @default.
• W1535818125 created "2016-06-24" @default.
• W1535818125 creator A5011548503 @default.
• W1535818125 creator A5055664540 @default.
• W1535818125 creator A5077698491 @default.
• W1535818125 date "1991-04-01" @default.
• W1535818125 modified "2023-09-24" @default.
• W1535818125 title "Coinfection with recombinant vaccinia viruses expressing poliovirus P1 and P3 proteins results in polyprotein processing and formation of empty capsid structures" @default.
• W1535818125 cites W1495304774 @default.
• W1535818125 cites W1499575726 @default.
• W1535818125 cites W1559988949 @default.
• W1535818125 cites W1560667925 @default.
• W1535818125 cites W1607574049 @default.
• W1535818125 cites W1756763717 @default.
• W1535818125 cites W1798612500 @default.
• W1535818125 cites W1846625983 @default.
• W1535818125 cites W1901698120 @default.
• W1535818125 cites W1958494624 @default.
• W1535818125 cites W1965372133 @default.
• W1535818125 cites W1966256798 @default.
• W1535818125 cites W1966339574 @default.
• W1535818125 cites W1974233081 @default.
• W1535818125 cites W2001303072 @default.
• W1535818125 cites W2004737963 @default.
• W1535818125 cites W2011719256 @default.
• W1535818125 cites W2041123313 @default.
• W1535818125 cites W2041302626 @default.
• W1535818125 cites W2043326986 @default.
• W1535818125 cites W2051468219 @default.
• W1535818125 cites W2064257293 @default.
• W1535818125 cites W2093399363 @default.
• W1535818125 cites W2122966339 @default.
• W1535818125 cites W2127067203 @default.
• W1535818125 cites W2159086417 @default.
• W1535818125 cites W2335724367 @default.
• W1535818125 doi "https://doi.org/10.1128/jvi.65.4.2088-2092.1991" @default.
• W1535818125 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/240068" @default.
• W1535818125 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1848318" @default.
• W1535818125 hasPublicationYear "1991" @default.
• W1535818125 type Work @default.
• W1535818125 sameAs 1535818125 @default.
• W1535818125 citedByCount "62" @default.
• W1535818125 countsByYear W15358181252013 @default.
• W1535818125 countsByYear W15358181252014 @default.
• W1535818125 countsByYear W15358181252015 @default.
• W1535818125 countsByYear W15358181252017 @default.
• W1535818125 countsByYear W15358181252018 @default.
• W1535818125 countsByYear W15358181252019 @default.
• W1535818125 countsByYear W15358181252020 @default.
• W1535818125 countsByYear W15358181252021 @default.
• W1535818125 countsByYear W15358181252022 @default.
• W1535818125 countsByYear W15358181252023 @default.
• W1535818125 crossrefType "journal-article" @default.
• W1535818125 hasAuthorship W1535818125A5011548503 @default.
• W1535818125 hasAuthorship W1535818125A5055664540 @default.
• W1535818125 hasAuthorship W1535818125A5077698491 @default.
• W1535818125 hasBestOaLocation W15358181251 @default.
• W1535818125 hasConcept C104317684 @default.
• W1535818125 hasConcept C153911025 @default.
• W1535818125 hasConcept C159047783 @default.
• W1535818125 hasConcept C202878990 @default.
• W1535818125 hasConcept C2522874641 @default.
• W1535818125 hasConcept C2779094796 @default.
• W1535818125 hasConcept C2779631682 @default.
• W1535818125 hasConcept C2779827044 @default.
• W1535818125 hasConcept C2781356689 @default.
• W1535818125 hasConcept C40767141 @default.
• W1535818125 hasConcept C55493867 @default.
• W1535818125 hasConcept C86803240 @default.
• W1535818125 hasConceptScore W1535818125C104317684 @default.
• W1535818125 hasConceptScore W1535818125C153911025 @default.
• W1535818125 hasConceptScore W1535818125C159047783 @default.
• W1535818125 hasConceptScore W1535818125C202878990 @default.
• W1535818125 hasConceptScore W1535818125C2522874641 @default.
• W1535818125 hasConceptScore W1535818125C2779094796 @default.
• W1535818125 hasConceptScore W1535818125C2779631682 @default.
• W1535818125 hasConceptScore W1535818125C2779827044 @default.
• W1535818125 hasConceptScore W1535818125C2781356689 @default.
• W1535818125 hasConceptScore W1535818125C40767141 @default.
• W1535818125 hasConceptScore W1535818125C55493867 @default.
• W1535818125 hasConceptScore W1535818125C86803240 @default.
• W1535818125 hasIssue "4" @default.
• W1535818125 hasLocation W15358181251 @default.
• W1535818125 hasLocation W15358181252 @default.
• W1535818125 hasLocation W15358181253 @default.
• W1535818125 hasLocation W15358181254 @default.
• W1535818125 hasOpenAccess W1535818125 @default.
• W1535818125 hasPrimaryLocation W15358181251 @default.
• W1535818125 hasRelatedWork W1756763717 @default.
• W1535818125 hasRelatedWork W1965597722 @default.
• W1535818125 hasRelatedWork W1985545133 @default.
• W1535818125 hasRelatedWork W2023089872 @default.
• W1535818125 hasRelatedWork W2083744328 @default.
• W1535818125 hasRelatedWork W2105527567 @default.
• W1535818125 hasRelatedWork W2112575263 @default.
• W1535818125 hasRelatedWork W2407030612 @default.
• W1535818125 hasRelatedWork W2413665266 @default.
• W1535818125 hasRelatedWork W2738758102 @default.

• next