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- W1535883567 abstract "Abstract The authors present data from 88 babies born to mothers taking lithium carbonate at least during the first trimester for the treatment or prophylaxis of manic-depressive illness. Six per cent manifested congenital malformations. This does not exceed the expected incidence of malformations in the general population of neonates. Since lithium teratogenicity is dose related, specific guidelines are presented for the use of lithium during pregnancy to insure the smallest adequate amounts and to avoid excessively high maternal serum lithium concentrations to which the fetus is exposed. Sodium-depleting diuretics and sodium-free diets are the commonest causes of maternal and/or neonatal lithium toxicity and are contraindicated in lithium-treated women. Lithium shoud be given to the pregnant woman in smaller doses, given more frequently to avoid high pulses being presented to the fetus; breast feeding should be avoided to prevent neonatal toxicity as lithium appears in the breast milk of lithium-treated mothers." @default.
- W1535883567 created "2016-06-24" @default.
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- W1535883567 date "1973-05-01" @default.
- W1535883567 modified "2023-09-25" @default.
- W1535883567 title "Lithium carbonate in obstetrics: Guidelines for clinical use" @default.
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- W1535883567 doi "https://doi.org/10.1016/0002-9378(73)90876-4" @default.
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